Author: "Alim A" / Topic: biology - Searchworks@Jio Institute Digital Library Search Results

702 results on '"Alim A"'

1. Integrated Nutrient Management Improves Productivity and Quality of Sugarcane (Saccharum Officinarum L.)

Author: Md. Ariful Islam, Mohamed M. Hassan, Akbar Hossain, Md. Shamsul Arefin, Md. Mokhlesur Rahman, Rajan Bhatt, Sabry Hassan, Mahmoud F. K. Soliman, and Md. Abdul Alim
Subjects: Saccharum officinarum, biology, Agronomy, Physiology, Nutrient management, media_common.quotation_subject, Environmental science, Quality (business), Plant Science, biology.organism_classification, Biochemistry, Productivity, media_common
Published: 2022
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2. Mental health and well-being during COVID-19 in the developing world: A review of Sub-Saharan Africa and Asia

Author: Nabat Arfi, Farzana Alim, and Shalini Agarwal
Subjects: Correlation, Nutrient, Rural community, Environmental health, Dietary diversity, Biology, human activities
Abstract: In view of the latest COVID-19 pandemic's unprecedented major global health crisis, it is extremely vital to consider the mental effect of this rising and formidable threat on the life of humanity, which has significant morbidity and mortality worldwide. Previous research indicates that people affected by COVID-19 can have a high burden of issues with mental health, including depression, anxiety disorders, stress, sleep disorders, emotional illness, signs of post-traumatic stress, and suicidal behavior. In the background of the COVID-19 pandemic, as the outbreak entails a large-scale change in behavior and further, creates major psychological burdens on individuals, there is a growing concern to resolve the mental health issues of the general population. This review article attempts to highlight different mental health challenges faced during COVID-19 by multiple individuals. In certain settings, virtual mental health systems should be set up, and social media should be used to provide education and networking tools for mental health. Psycho pathological issues in various communities should be emphasized in future epidemiological research.
Published: 2021
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3. Coat Polymorphism in Eurasian Lynx: Adaptation to Environment or Phylogeographic Legacy?

Author: Romane Darul, Vazha Kochiashvili, Krzysztof Schmidt, José A. Godoy, Alexander P. Saveljev, Muzigit I. Akkiev, Guna Bagrade, Peep Männil, Bledi Hoxha, Mehmet Kürşat Şahin, Giorgi Sulamanidze, Naranbaatar Galsandorj, Yuriy A. Yarovenko, John D. C. Linnell, Mohammad S. Farhadinia, Innokentiy M. Okhlopkov, Ivan V. Seryodkin, Aleksandër Trajçe, Mirosław Ratkiewicz, Sergey A. Trepet, Igor Khorozyan, Tomáš Jászay, Aleksandar Stojanov, Henryk Okarma, Dime Melovski, Janis Ozolins, Mikhail G. Dvornikov, Aivars Ornicans, Jimsher Mamuchadze, Alexander Gavashelishvili, Alim B. Pkhitikov, and Şahin, Mehmet Kürşat
Subjects: 0106 biological sciences, Camouflage, Coat, VDP::Zoologiske og botaniske fag: 480, Pelage polymorphism, Zoology, Biology, 010603 evolutionary biology, 01 natural sciences, 03 medical and health sciences, biology.animal, Mammal coloration, Glacial period, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, 0303 health sciences, Eurasian lynx, Last glacial maximum, Last Glacial Maximum, Phylogeography, Habitat, Habitat suitability, VDP::Zoology and botany: 480, Mammal, Genetic drift, Adaptation
Abstract: We studied the relationship between the variability and contemporary distribution of pelage phenotypes in one of most widely distributed felid species and an array of environmental and demographic conditions. We collected 672 photographic georeferenced records of the Eurasian lynx throughout Eurasia. We assigned each lynx coat to one of five phenotypes. Then we fitted the coat patterns to different environmental and anthropogenic variables, as well as the effective geographic distances from inferred glacial refugia. A majority of lynx were either of the large spotted (41.5%) or unspotted (uniform, 36.2%) phenotype. The remaining patterns (rosettes, small spots and pseudo-rosettes) were represented in 11.0%, 7.4%, and 3.9% of samples, respectively. Although various environmental variables greatly affected lynx distribution and habitat suitability, it was the effect of least-cost distances from locations of the inferred refugia during the Last Glacial Maximum that explained the distribution of lynx coat patterns the best. Whereas the occurrence of lynx phenotypes with large spots was explained by the proximity to refugia located in the Caucasus/Middle East, the uniform phenotype was associated with refugia in the Far East and Central Asia. Despite the widely accepted hypothesis of adaptive functionality of coat patterns in mammals and exceptionally high phenotypic polymorphism in Eurasian lynx, we did not find well-defined signs of habitat matching in the coat pattern of this species. Instead, we showed how the global patterns of morphological variability in this large mammal and its environmental adaptations may have been shaped by past climatic change.
Published: 2021
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4. Fermented earthworms as a feed additive enhances non-specific immune response in catfish (Clarias gariepinus)

Author: Alim Isnansetyo, Mukhlisna Djalil, Triyanto, and Tito Aria Nugraha
Subjects: Clarias gariepinus, medicine.diagnostic_test, Super oxide dismutase, Feed additive, Aquatic Science, Hematocrit, Biology, biology.organism_classification, Respiratory burst, Walking catfish, Animal science, medicine, Agronomy and Crop Science, Completely randomized design, Catfish
Abstract: Catfish which is an important component of global freshwater aquaculture production is also prone to a wide range of diseases resulting in economic losses. Improvement of the immune status of catfish is a promising preventive approach to control disease. The purpose of this study was to determine the effect of fermented earthworms as a feed additive on the non-specific immune response of walking catfish (Clarias gariepinus). Earthworms were fermented by inoculation with a bacterial mixture of Bacillus spp. and Lactococcus raffinolactis. The study featured a completely randomized design, with five treatments in quadruplicate. The various treatments consisted of fermented earthworms supplemented (FE) at at 0%, 2.5%, 5%, 7.5%, and 10% (w/w). Catfish with an average weight of 15 g were stocked at a density of 50 fish per 50 L/tank, reared for 2 months, and fed thrice a day at a feeding rate of 3% of total boby weight. The parameters observed included phagocytic activity (PA), phagocytic index (PI), extracellular respiratory burst, leucocyte differentiation, super oxide dismutase (SOD), natural agglutination, leucocrit, and hematocrit. Results showed that that FE supplemented at 2.5% significantly increased the respiratory burst activity, hematocrit, PA, PI, SOD, and leucocyte differentiation (P
Published: 2021
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5. Microbiological Quality Assessment and Identification of Antibiotic Resistant Bacteria at Different Stages of the Milk Supply Chain in Dhaka City of Bangladesh

Author: Raisa Binte Iqbal, Sharmin Rumi Alim, Abira Nowar, and Ila Ismail
Subjects: Antibiotic resistance, business.industry, law, food and beverages, Pasteurization, Identification (biology), General Medicine, Microbiological quality, Biology, business, Biotechnology, Milk supply, law.invention
Abstract: Aims: Milk works as an excellent medium for bacterial growth and can turn into a fatal source of food borne diseases when consumed without pasteurization. This study was carried out to examine the microbiological quality of milk from three different points of milk supply chain to investigate whether the dairy stakeholders are maintaining the consumer safety or not. Study Design: A cross sectional study Place and Duration: The study took place at the Food Microbiology lab of Institute of Nutrition and Food Science, University of Dhaka from November 2019 to February 2020. Methodology: A total of 60 samples were studied including raw milk from collection centers, unpackaged pasteurized milk from processing plants and packaged pasteurized milks from retail shops. After carrying out the microbiological analysis the samples were examined for determining the total bacterial count (TBC) and total coliform count (TCC). Antibiotic susceptibility test was done using disk diffusion assay and detection of virulent gene in Salmonella spp. was done by Polymerase Chain Reaction (PCR) using specific invA primer. Results: The results revealed that all raw milk samples were substandard in terms of TBC and TCC and pasteurized milks from processing plants maintained the standard quality. Importantly, packaged pasteurized milk samples from retail shops had high TBC (>4.0× 104 CFU/mL) and TCC (1.2×103 CFU/mL) containing Pseudomonas, Micrococcus, Streptococcus, Salmonella, Proteus, Staphylococcus, Bacillus and E. coli. Bacteria like Salmonella (75%), Proteus (62.5%) and Vibrio (62.5%) possessed high Multiple Antibiotic Resistance (MAR) index and showed resistance towards antibiotics namely Ampicillin, Amoxicillin, Erythromycin and Colistin. Through further molecular analysis we detected invA virulent gene one of the Salmonella isolates which was collected from the pasteurized milk samples of the retail shops. Conclusion: High bacterial load in raw milk and packaged pasteurized milk indicate that the milk we consume is substandard in microbiological quality. Precautionary measurements and careful processing of milk may reduce the prevalence of microbiological contamination in the milk supply chain.
Published: 2021
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6. Comparison of Novel Sandfly Control Interventions: A Pilot Study in Bangladesh

Author: Piero Olliaro, Dinesh Mondal, Almahmud, M. Mamun Huda, Greg Matlashewski, Debashis Ghosh, Christine Halleux, Axel Kroeger, and Abdul Alim
Subjects: Insecticides, Density reduction, Indoor residual spraying, Psychological intervention, Pilot Projects, Insect Control, Study methods, Virology, Environmental health, parasitic diseases, Nitriles, Pyrethrins, medicine, Animals, Insecticide-Treated Bednets, Duration of effect, Bangladesh, biology, Relative efficacy, business.industry, Construction Materials, Articles, biology.organism_classification, medicine.disease, Sandfly, Insect Vectors, Infectious Diseases, Visceral leishmaniasis, Phlebotomus, Housing, Leishmaniasis, Visceral, Parasitology, Psychodidae, business
Abstract: In this pilot comparative study, we investigated and compared the effects of existing vector control tools on sandfly densities and mortality to inform and support the National Kala-azar Elimination Program (NKEP). The interventions included insecticidal wall painting (IWP), reduced-coverage insecticidal durable wall lining (DWL), insecticide-impregnated bednets (ITN), and indoor residual spraying with deltamethrin (IRS). Sakhua union with seven villages was the study area, which was the most highly endemic visceral leishmaniasis union in Trishal upazila, Bangladesh. Each cluster containing the different interventions included approximately 50 households. Study methods included random selection of clusters, collection of sandfly by CDC light trap and manual aspirator to determine sandfly density, and sandfly mortality determined by WHO cone bioassay test. Trained field research assistants interviewed household heads using structured questionnaires for sociodemographic information, as well as safety and acceptability of the interventions. Descriptive and analytical statistical methods measured interventions’ effect and its duration on sandfly density reduction and mortality. We measured the relative efficacy of IWP on sandfly control against DWL, ITN, and IRS by the difference-in-difference regression model. We found that existing interventions were effective and safe for sandfly control with different duration of effect and acceptability. The relative efficacy of IWP for sandfly reduction varied by –59% to –91%, –75% to –81%, and –30% to –104% compared with DWL, ITN, and IRS, respectively, at different time points during the 12-month follow-up. These study results will guide the NKEP for selection of sandfly control tool(s) in its subsequent consolidation and maintenance phases.
Published: 2021

7. Zoonotic Surveilance (Brucellosis) in Enrekang District South Sulawesi Province

Author: Nurhayati Nurhayati, Rosmiaty Rosmiaty, Muhasirah Muhasirah, and Nur Alim Ahzan
Subjects: Veterinary medicine, medicine, Brucellosis, Biology, medicine.disease
Abstract: Brucellosis merupakan penyakit zoonosis yang disebabkan oleh bakteri genus brucella, brucellosis dapat menular dari hewan ke manusia. Tujuan penelitian untuk mengetahui risiko penularan brucellosis pada peternak, pekerja peternakan dan petugas kesehatan hewan di Kabupaten Enrekang Propinsi Sulawesi Selatan. Metode Sampel darah diambil dengan menggunakan tenaga analis dengan tabung vakutainer, kemudian dilakukan centrifuge dan dibiarkan pada temperatur kamar sampai terbentuk serum. Serum kemudian di tetesi dengan RBT pada slide, hasil RBT positif kemudian diuji konfirmasi dengan dengan PCR-Konvensional di Laboratorium Balai Teknik Kesehatan Lingkungan dan Pengendalian Penyakit Kelas I Makassar. Hasil penelitian berdasarkan uji RBT (Rose Bengal Test) didapatkan 3 sampel positif dengan kategori positif +++ dan 1 sampel dengan kategori positif ++. dan setelah dilakukan uji konfirmasi terhadap sampel dengan metode PCR Konvensional didapatkan 2 sampel positif. Kesimpulan: Terdapat kasus penularan brucellosis pada peternak dan petugas kesehatan hewan di Kabupaten Enrekang.
Published: 2021
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8. Skirining fitokimia ekstrak etanol kulit buah sirsak (Annona muricata Linn) dan uji aktivitas antioksidan dengan metode DPPH

Author: Nurul Jummah, Nur Alim, Nurdiyanti Nurdiyanti, and Agus Sangka Pratama
Subjects: Antioxidant, Traditional medicine, biology, DPPH, medicine.medical_treatment, Building and Construction, biology.organism_classification, Terpenoid, chemistry.chemical_compound, chemistry, Phytochemical, medicine, Electrical and Electronic Engineering, Annona muricata
Abstract: Phytochemical screening research on the ethanol extract of soursop (Annona muricata Linn) peel and antioxidant activity was tested using the DPPH method. The purpose of this study was to determine several classes of compounds found in soursop rind and to determine the antioxidant activity of ethanol extract of soursop rind against DPPH free radicals. The results showed ethanol extract of positive soursop fruit skin containing flavonoids, tannins, and terpenoids. of soursop fruit skin extract was carried out by DPPH method results obtained IC50 value of 192.13 µg / mL ± 5.198137 which was categorized as weak.
Published: 2021
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9. The Effects of Cold Stratification, Cold Storage and Gibberellic acid (GA3) on Seed Germination of Bilberry (Vaccinium myrtillus L.)

Author: Esra Alim and Serap Bilgin
Subjects: Horticulture, chemistry.chemical_compound, Stratification (seeds), Bilberry, chemistry, biology, Germination, Cold storage, General Medicine, Vaccinium myrtillus, biology.organism_classification, Gibberellic acid
Abstract: Aim of study: The effects of cold stratification, cold storage and gibberellic acid (GA3) on seed germination of bilberry (Vaccinium myrtillus L.) were investigated. Area of study: Ripe berries of V.myrtillus were collected from the Kaz Mountains (İda Mount) National Park-Balıkesir province in Turkey. Material and methods: In the study five levels of cold moist stratification period, cold dry storage period (control, 15, 30, 60, 90 days) at +4 ºC and three dose of GA3 (control, 500, 1000, 1500 mg/L) treatments were applied. Data were tested independently by ANOVA according to three factors with three replications. 50 seeds were used for each treatment for each replication. Main results: Cold stratifications, cold storage and GA3 treatments did not increase the germination percentage of bilberry seeds. Germination was found between 23-40% in all experiments. Highlights: Different pretreatments are advised for increasing germination percentage of V. myrtillus L. seeds
Published: 2021
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10. Isolation and Molecular Characterization of Fowl Adenoviruses Associated with Inclusion Body Hepatitis-hydropericardium Syndrome in Broiler Chickens in Egypt

Author: Eman A Morsy, Mahmoud Samir, Diaa G. Khelfa, Marwa S. Khattab, Mostafa G. Al Naguib, and Gomaa A. Abdel-Alim
Subjects: Hepatitis, General Veterinary, biology, Isolation (health care), Fowl, medicine, Broiler, biology.organism_classification, medicine.disease, Virology
Abstract: Avian adenoviruses are an extremely diversified group of pathogens that recently triggering a variety of problems for poultry production. In particular, Inclusion Body Hepatitis-Hydropericardium Syndrome (IBH-HPS), which has been observed in broiler birds from 3 to 6 weeks of age and is associated with anemia, hemorrhagic disorders, hydropericardium, and high mortality. The disease has been reported worldwide, and recently it was reported in many Egyptian farms, causing severe economic losses. Therefore, the current study aimed to isolate, and genetically type the most common Adenovirus serotypes associated with this syndrome in Egyptian farms. A total of 50 broiler chicken farms (3-6 weeks old) located in different Egyptian governorates were examined. Macroscopically, the diseased flock revealed hydropericardium, enlarged friable livers with ecchymotic hemorrhages, and varying mortality rates (1 to 7.5%). Histopathologically, severe diffuse necrotizing enteritis, hepatitis, pericarditis, and diffuse lymphoid depletion of the spleen were the most prominent lesions. Liver tissues and cloacal swabs were collected from all examined flocks for FAdVs detection by conventional polymerase chain reaction (PCR) targeting the L1 loop in the hexon gene. The PCR products were sequenced for typing of the detected viruses. It was found that 10 out of 50 flocks examined were PCR positive for FAdVs (20%). Phylogenetic analysis of the sequenced genes revealed that the obtained viruses clustered with reference strains belonging to FAdV type D and E serotype 2, 11, and 8a respectively. The isolation of both FAdV type D and FAdV type E were carried out on a primary cell culture chicken embryo liver cell (CEL) and the presence of these viruses was confirmed by PCR after the appearance of cytopathic effect (CPE). From this study, it could be concluded that both FAdVs types D and E are the most common adenoviruses circulating in poultry farms suffering from hydropericardium and inclusion body hepatitis.
Published: 2021
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11. Rudimentary Pharmacological Inspection of the Ethanolic Extract of Grewia hirsute Vhal

Author: Mohammad Abdul Alim, Munny Das, Md. Sohanur Rahman, Wahida Akter, Sumiya Alam, Rayhana Begum, Mst. Marium Begum, Md. Marufur Rahman Moni, Md. Razu Ahmed, Abdullah Al Mamun, and Azharul Islam
Subjects: Glucose tolerance test, biology, medicine.diagnostic_test, business.industry, Pharmacology, biology.organism_classification, medicine.disease, Acute toxicity, Metformin, Grewia, Simvastatin, In vivo, Diabetes mellitus, medicine, business, Omeprazole, medicine.drug
Abstract: Background: Screening of plant kingdom for various pharmacologic activities with an aim of discovering new active constituents is a continuous process and a part of systemic analysis. Purpose: The purpose of this study was to investigate hypoglycemic, hypolipidemic, anti-ulcer, and thrombolytic effects of the ethanolic extract of Grewia hirsuta Vahl. (EEGH) in different in vivo and in vitro paradigms in both Swiss Albino mice and Long Evans rats. Materials and Methods: After an oral acute toxicity study, adult male mice and rats according to the testing procedure were treated with EEGH (200, 400, 2000 and 4000 mg/kg, p.o.) and (1000 mg/70kg B.W. p.o Metformin, 10 mg/70kg, B.W. p.o Simvastatin, and 30 mg/70kg, B.W. p.o Omeprazole), and subjected to three in vivo tests and one in vitro test according to various established testing protocol. Results: After testing glucose tolerance test, for hypoglycemic activities, 400 mg/kg EEGH both in 6 weeks and 12 weeks exhibited moderate anti-diabetic effect (8.89 ± 0.09 and 8.12±0.28 mmol/L respectively). Additionally, combination therapy of both 400 mg/kg EEGH + Metformin revealed a substantial fall of sugar level from 16.78± 0.1 to 6.4 ± 0.04 mmol/L, confirming a sign of moderate potentiation. No lipid-lowering effect was observed in the timed-treatment procedure. In the anti-ulcer effect, n-butanol showed a comparable ulcer inhibition index (90.56%) compared to the standard Omeprazole inhibition index of 91%. Additionally, ethyl acetate fraction showed 62% and 66% clot lysis capacity by 200 and 400 mg/kg EEGH, whereas standard Streptokinase’s capacity was 80%. The EEGH showed notable anti-ulcer activities and moderate anti-diabetic and thrombolytic activities. Conclusion: Results extend the current understanding of the impacts of Grewia hirsuta Vahl. on biological parameters and indicate that this plant might be promising for the management of diabetes mellitus, anticoagulant, and gastric ulcer disorders prominently.
Published: 2021
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12. Molecular detection of Toxoplasma gondii in aborted fetuses of goats in Chattogram, Bangladesh

Author: Delower Hossain, Tanjila Hasan, Abdul Mannan, Md. Monir Hossan, Ahm Musleh Uddin, Azizunnesa Rekha, and Mohammad Abdul Alim
Subjects: Veterinary medicine, Physiology, aborted fetus, Abortion, SF1-1100, Placenta, parasitic diseases, SF600-1100, medicine, Parasite hosting, reproductive and urinary physiology, nested polymerase chain reaction, General Veterinary, biology, business.industry, toxoplasma gondii, Aborted Fetus, goat, Toxoplasma gondii, biology.organism_classification, medicine.disease, Toxoplasmosis, Animal culture, medicine.anatomical_structure, embryonic structures, Livestock, business, Nested polymerase chain reaction, Research Article
Abstract: Background and Aim: Toxoplasma gondii is a protozoan parasite that is responsible for the major cause of congenital diseases, abortion, and stillbirth in humans and farm animals. Primary infection in pregnant goats due to T. gondii leads to abortion and significant economic losses in the livestock industry. Moreover, very few studies have been performed for the identification of T. gondii from aborted fetuses of goats. The study was conducted for the molecular identification of Toxoplasma gondii from aborted fetuses of goats in Chattogram, Bangladesh. Materials and Methods: Twenty aborted fetuses of goats were collected from 52 farms in the study area. A nested polymerase chain reaction (PCR) assay targeting the B1 gene was performed, and a positive sample yield of 197 bp amplified DNA products consistent with T. gondii. Results: The overall prevalence of toxoplasmosis in the aborted fetus of goats was 35.0%. Heart muscle, liver, brain, and placenta showed positive PCR results. The risk factors related to the does age, presence of cats in farms, and aborted fetus age were found to be statistically significant (p
Published: 2021

13. Phytochemical profiling, antioxidant potentiality and antibacterial activity of the ethanolic extracts of Rosenvingea sp. of Bay of Bengal

Author: Toufiqul Islam, Tamim Ahsan, Farzanoor Rahman, Morshedul Alam, Abdul Alim, and Mohammad Nazir Hossain
Subjects: Antioxidant, Phytochemical, Traditional medicine, Rosenvingea, medicine.medical_treatment, BENGAL, medicine, Biology, Antibacterial activity, Bay
Abstract: The objective of the present study was to explore the phytochemical profiling, antioxidant and antimicrobial activity of 50% ethanolic extract of Rosenvingea sp. found in the Bay of Bengal of Bangladesh. Seven phytochemicals were tested from the ethanolic extract of Rosenvingea, where four phytochemicals, namely steroid, glycosides, alkaloids, and tannins were present. However, ethanol extract exhibited low antioxidant activity compared to standard ascorbic acid as measured by DPPH-Free radical scavenging assay. In Brine Shrimp lethality bioassay, 50% ethanolic extract showed an LC50 value of 10.88 mg/mL, whereas positive control (K2Cr2O7) showed LC50 59.97 µg/mL suggesting the less toxic property of the ethanolic extract. In-vitro antimicrobial activity of ethanolic extract of Rosenvingea sp. was investigated against gram-positive and gram-negative bacteria species (Staphylococcus, Bacillus, Pseudomonas, Salmonella, and Klebsiella) by agar disc diffusion method. The highest antibacterial activity was noticed against Klebsiella pneumonia, Pseudomonas aeruginosa, Staphylococcus hominis with a zone of inhibition of 5.00±1.00 mm, 3.66±0.57 mm, and 3.33±0.57 mm, respectively. This is the first study on Rosenvingea sp. from the Bay of Bengal, reporting its phytochemical, antioxidant, and antimicrobial potentiality. However, more study is required to elucidate its commercial viability in the food and medicine industries. J. Bangladesh Acad. Sci. 45(1); 59-71: June 2021
Published: 2021
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14. Potency of Three Botanical Oils Against the Aphis Craccivora Koch (Homoptera: Aphididae) Nymphs Under Laboratory Conditions

Author: Md. Alamgir Hossain, Md. Abdul Alim, Maa Bachchu, and Yasmin
Subjects: Horticulture, biology, Homoptera, fungi, Potency, Aphididae, biology.organism_classification, Nymph, Aphis craccivora, Industrial and Manufacturing Engineering
Abstract: Botanicals are promising and attractive alternatives for pest management. In the present study, three botanical oils namely neem (Azadirachta indica), karanja (Pongamia pinnata) and mehogony (Swietenia mahagoni) were tested against the nymphs of Aphis craccivora Koch to evaluate the toxic and repellent effects under laboratory conditions (25 ± 5oC, 65-75% RH). Four concentrations (0.5, 1.0, 1.5, and 2.0%) along with control were maintained with distilled water and tween-20 was used as emulsifier. Leaf dipped method were used for insect bioassay. Insect mortality was recorded at 24, 48 and 72 hours after intervals while repellency was carried out at 2 hours after intervals upto 10th hours and the collected data were analyzed through MSTAT-C program. Results indicated that all the tested oils had toxic and repellent effects against the A. craccivora nymphs. Among the tested botanical oils, no significant difference was observed in terms of mortality over treatment time. But significant difference was noticed over level of concentrations exerted by the botanical oils. The average highest mortality (28.62%) was recorded by the application of mehogony oil whereas neem oil showed the lowest mortality (27.21%) against the A. craccivora and the mortality was directly proportional to the level of concentrations and hour after treatment (HAT). Probit analysis showed the lowest LD50 values of mehogony oil which revealed the highest toxic effect against the nymph of bean aphid. The highest repellent effect (77.33%) was found in mehogony oil (repellent class IV) among all the botanical oils applied. On the contrary, neem (57.33%) and karanja (55.00%) oils belonged to the same repellent class that is repellent class II. Although all the tested botanical oils evaluated showed toxic and repellent effects but mehogony oil performed as the best potent oil against the nymphs. We therefore suggested using the mehogony oil for the management of bean aphid. SAARC J. Agric., 19(1): 139-154 (2021)
Published: 2021
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15. Efficacy of some pesticides against Tetranychus urticae Koch (Acari: Tetranychidae) and their residual effects on Coccinella septempunctata (L.) (Coleoptera: Coccinellidae)

Author: Md. Abdul Alim, Md. Nizam Uddin, Alina Rabbi, Mohammad Mosharof Hossain Bhuyain, Md. Adnan Al Bachchu, and Sharmin Akter
Subjects: Spinosad, Chlorfenapyr, Biology, Pesticide, biology.organism_classification, Coccinella septempunctata, Toxicology, chemistry.chemical_compound, chemistry, Imidacloprid, Insect Science, medicine, Abamectin, Tetranychus urticae, Thiamethoxam, Ecology, Evolution, Behavior and Systematics, medicine.drug
Abstract: Pesticides are used to control Tetranychus urticae Koch populations in country bean, Dolichos lablab (L.). The results of using pesticides are more predictable if there is detailed information about their toxicity and specificity. In particular, the degree of pesticide exposure is associated with the adult stages of T. urticae and natural enemies, while determining the overall efficacy of pesticide use. The present study was carried out to determine the direct and residual effects of seven pesticides, namely abamectin, abamectin + bifenthrin, spinosad, chlorfenapyr, deltamethrin, imidacloprid and thiamethoxam against Tetranychus urticae Koch (Acari: Tetranychidae) and residual toxicity of these pesticides against the pest and its predator Coccinella septempunctata (L.) (Coleoptera: Coccinellidae) adults. In the laboratory trials, abamectin caused 100% mortality of T. urticae within 3 h, abamectin + bifenthrin within 6 h and other pesticides within 48 h except for imidacloprid and thiamethoxam. When the toxicity of T. urticae eggs was examined, the egg mortality for all pesticide treatments was significantly higher than the control. Abamectin + bifenthrin and chlorfenapyr caused 100% egg mortality followed by application of abamectin (95%) and deltamethrin (82%). On the other hand, thiamethoxam, imidacloprid and spinosad showed 63%, 65% and 71% egg mortality, respectively. In potted bean plants, abamectin, abamectin + bifenthrin and chlorfenapyr showed significant mortality of T. urticae over control up to 21 days and the rest of the pesticides showed up to 14 days. Abamectin and chlorfenapyr showed higher residual efficacy against T. urticae but low toxicity against C. septempunctata. Imidacloprid had the longest residual effect on adults of C. septempunctata causing 20% mortality after 21 days, but low toxicity against T. urticae. Abamectin + bifenthrin residue caused > 20% mortality of C. septempunctata after 14 days of exposure. Therefore, abamectin and chlorfenapyr can be used for the management of T. urticae because of their higher toxicity against T. urticae and low residual activity against C. septempunctata.
Published: 2021
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16. Characterization of Spatial and Temporal Variability of Crassostrea spp. Spat Settlement to Ascertain Allocable Sites for Spat Collection at Cox’s Bazar, Bangladesh

Author: Tashrif Mahmud Minhaz, Joyshri Sarker, Mohammed Nurul Absar Khan, Mohammad Redwanur Rahman, Helena Khatoon, Moin Uddin Ahmad, Abdul Alim, and S M Khalequzzaman
Subjects: Fishery, Settlement (structural), Crassostrea, Aquatic Science, Biology, biology.organism_classification
Published: 2021
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17. Differential Inhibition of Equilibrative Nucleoside Transporter 1 (ENT1) Activity by Tyrosine Kinase Inhibitors

Author: Claire Denizot, Karima Alim, Amélie Moreau, Olivier Fardel, Yannick Parmentier, Elodie Jouan, Arnaud Bruyère, Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), École des Hautes Études en Santé Publique [EHESP] (EHESP), Technologie Servier, Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Chard-Hutchinson, Xavier
Subjects: Lactams, [SDV]Life Sciences [q-bio], Aminopyridines, Pharmacology, Equilibrative nucleoside transporter 1, Equilibrative Nucleoside Transporter 1, 03 medical and health sciences, Gene Knockout Techniques, Inhibitory Concentration 50, 0302 clinical medicine, In vivo, Tandem Mass Spectrometry, Cell Line, Tumor, Humans, Pharmacology (medical), Original Research Article, Equilibrative-Nucleoside Transporter 2, Protein Kinase Inhibitors, 030304 developmental biology, 0303 health sciences, biology, Dose-Response Relationship, Drug, Chemistry, Transporter, Equilibrative nucleoside transporter, Lorlatinib, In vitro, respiratory tract diseases, [SDV] Life Sciences [q-bio], 030220 oncology & carcinogenesis, biology.protein, Pyrazoles, Nucleoside, Tyrosine kinase, Chromatography, Liquid
Abstract: International audience; Background and Objectives Equilibrative nucleoside transporter (ENT) 1 is a widely-expressed drug transporter, handling nucleoside analogues as well as endogenous nucleosides. ENT1 has been postulated to be inhibited by some marketed tyrosine kinase inhibitors (TKIs). To obtain insights into this point, the interactions of 24 TKIs with ENT1 activity have been analyzed. Methods Inhibition of ENT1 activity was investigated in vitro through quantifying the decrease of [H-3]-uridine uptake caused by TKIs in HAP1 ENT2-knockout cells, exhibiting selective ENT1 expression. TKI effects towards ENT1-mediated transport were additionally characterized in terms of their in vivo relevance and of their relationship to TKI molecular descriptors. Putative transport of the TKI lorlatinib by ENT1/ENT2 was analyzed by LC-MS/MS. Results Of 24 TKIs, 12 of them, each used at 10 mu M, were found to behave as moderate or strong inhibitors of ENT1, i.e., they decreased ENT1 activity by at least 35%. This inhibition was concentration-dependent for at least the strongest ones (IC50 less than 10 mu M) and was correlated with some molecular descriptors, especially with atom-type E-state indices. Lorlatinib was notably a potent in vitro inhibitor of ENT1/ENT2 (IC50 values around 1.0-2.5 mu M) and was predicted to inhibit these nucleoside transporters at relevant clinical concentrations, without, however, being a substrate for them. Conclusion Our data unambiguously add ENT1 to the list of drug transporters inhibited by TKIs, especially by lorlatinib. This point likely merits attention in terms of possible drug-drug interactions, notably for nucleoside analogues, whose ENT1-mediated uptake into their target cells may be hampered by co-administrated TKIs such as lorlatinib.
Published: 2021
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18. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Author: Klionsky, Daniel, Abdel-Aziz, Amal Kamal, Abdelfatah, Sara, Abdellatif, Mahmoud, Abdoli, Asghar, Abel, Steffen, Abeliovich, Hagai, Abildgaard, Marie, Abudu, Yakubu Princely, Acevedo-Arozena, Abraham, Adamopoulos, Iannis, Adeli, Khosrow, Adolph, Timon, Adornetto, Annagrazia, Aflaki, Elma, Agam, Galila, Agarwal, Anupam, Aggarwal, Bharat, Agnello, Maria, Agostinis, Patrizia, Agrewala, Javed, Agrotis, Alexander, Aguilar, Patricia, Ahmad, S Tariq, Ahmed, Zubair, Ahumada-Castro, Ulises, Aits, Sonja, Aizawa, Shu, Akkoc, Yunus, Akoumianaki, Tonia, Akpinar, Hafize Aysin, Al-Abd, Ahmed, Al-Akra, Lina, Al-Gharaibeh, Abeer, Alaoui-Jamali, Moulay, Alberti, Simon, Alcocer-Gómez, Elísabet, Alessandri, Cristiano, Ali, Muhammad, Alim Al-Bari, M Abdul, Aliwaini, Saeb, Alizadeh, Javad, Almacellas, Eugènia, Almasan, Alexandru, Alonso, Alicia, Alonso, Guillermo, Altan-Bonnet, Nihal, Altieri, Dario, Álvarez, Élida, Alves, Sara, Alves Da Costa, Cristine, Alzaharna, Mazen, Amadio, Marialaura, Amantini, Consuelo, Amaral, Cristina, Ambrosio, Susanna, Amer, Amal, Ammanathan, Veena, An, Zhenyi, Andersen, Stig, Andrabi, Shaida, Andrade-Silva, Magaiver, Andres, Allen, Angelini, Sabrina, Ann, David, Anozie, Uche, Ansari, Mohammad, Antas, Pedro, Antebi, Adam, Antón, Zuriñe, Anwar, Tahira, Apetoh, Lionel, Apostolova, Nadezda, Araki, Toshiyuki, Araki, Yasuhiro, Arasaki, Kohei, Araújo, Wagner, Araya, Jun, Arden, Catherine, Arévalo, Maria-Angeles, Arguelles, Sandro, Arias, Esperanza, Arikkath, Jyothi, Arimoto, Hirokazu, Ariosa, Aileen, Armstrong-James, Darius, Arnauné-Pelloquin, Laetitia, Aroca, Angeles, Arroyo, Daniela, Arsov, Ivica, Artero, Rubén, Asaro, Dalia Maria Lucia, Aschner, Michael, Ashrafizadeh, Milad, Ashur-Fabian, Osnat, Atanasov, Atanas, Au, Alicia, Auberger, Patrick, Auner, Holger, Aurelian, Laure, Autelli, Riccardo, Avagliano, Laura, Ávalos, Yenniffer, Aveic, Sanja, Aveleira, Célia Alexandra, Avin-Wittenberg, Tamar, Aydin, Yucel, Ayton, Scott, Ayyadevara, Srinivas, Azzopardi, Maria, Baba, Misuzu, Backer, Jonathan, Backues, Steven, Bae, Dong-Hun, Bae, Ok-Nam, Bae, Soo Han, Baehrecke, Eric, Baek, Ahruem, Baek, Seung-Hoon, Baek, Sung Hee, Bagetta, Giacinto, Bagniewska-Zadworna, Agnieszka, Bai, Hua, Bai, Jie, Bai, Xiyuan, Bai, Yidong, Bairagi, Nandadulal, Baksi, Shounak, Balbi, Teresa, Baldari, Cosima, Balduini, Walter, Ballabio, Andrea, Ballester, Maria, Balazadeh, Salma, Balzan, Rena, Bandopadhyay, Rina, Banerjee, Sreeparna, Banerjee, Sulagna, Bánréti, Ágnes, Bao, Yan, Baptista, Mauricio, Baracca, Alessandra, Barbati, Cristiana, Bargiela, Ariadna, Barilà, Daniela, Barlow, Peter, Barmada, Sami, Barreiro, Esther, Barreto, George, Bartek, Jiri, Bartel, Bonnie, Bartolome, Alberto, Barve, Gaurav, Basagoudanavar, Suresh, Bassham, Diane, Bast, Robert, Basu, Alakananda, Batoko, Henri, Batten, Isabella, Baulieu, Etienne, Baumgarner, Bradley, Bayry, Jagadeesh, Beale, Rupert, Beau, Isabelle, Beaumatin, Florian, Bechara, Luiz, Beck, George, Beers, Michael, Begun, Jakob, Behrends, Christian, Behrens, Georg, Bei, Roberto, Bejarano, Eloy, Bel, Shai, Behl, Christian, Belaid, Amine, Belgareh-Touzé, Naïma, Bellarosa, Cristina, Belleudi, Francesca, Belló Pérez, Melissa, Bello-Morales, Raquel, Beltran, Jackeline Soares de Oliveira, Beltran, Sebastián, Benbrook, Doris Mangiaracina, Bendorius, Mykolas, Benitez, Bruno, Benito-Cuesta, Irene, Bensalem, Julien, Berchtold, Martin, Berezowska, Sabina, Bergamaschi, Daniele, Bergami, Matteo, Bergmann, Andreas, Berliocchi, Laura, Berlioz-Torrent, Clarisse, Bernard, Amélie, Berthoux, Lionel, Besirli, Cagri, Besteiro, Sebastien, Betin, Virginie, Beyaert, Rudi, Bezbradica, Jelena, Bhaskar, Kiran, Bhatia-Kissova, Ingrid, Bhattacharya, Resham, Bhattacharya, Sujoy, Bhattacharyya, Shalmoli, Bhuiyan, Md Shenuarin, Bhutia, Sujit Kumar, Bi, Lanrong, Bi, Xiaolin, Biden, Trevor, Bijian, Krikor, Billes, Viktor, Binart, Nadine, Bincoletto, Claudia, Birgisdottir, Asa, Bjorkoy, Geir, Blanco, Gonzalo, Blas-Garcia, Ana, 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Ignacio, Ramsden, David, Randow, Felix, Rangarajan, Pundi, Ranieri, Danilo, Rao, Hai, Rao, Lang, Rao, Rekha, Rathore, Sumit, Ratnayaka, J Arjuna, Ratovitski, Edward, Ravanan, Palaniyandi, Ravegnini, Gloria, Ray, Swapan, Razani, Babak, Rebecca, Vito, Reggiori, Fulvio, Régnier-Vigouroux, Anne, Reichert, Andreas, Reigada, David, Reiling, Jan, Rein, Theo, Reipert, Siegfried, Rekha, Rokeya Sultana, Ren, Hongmei, Ren, Jun, Ren, Weichao, Renault, Tristan, Renga, Giorgia, Reue, Karen, Rewitz, Kim, Ribeiro de Andrade Ramos, Bruna, Riazuddin, S Amer, Ribeiro-Rodrigues, Teresa, Ricci, Jean-Ehrland, Ricci, Romeo, Riccio, Victoria, Richardson, Des, Rikihisa, Yasuko, Risbud, Makarand, Risueño, Ruth, Ritis, Konstantinos, Rizza, Salvatore, Rizzuto, Rosario, Roberts, Helen, Roberts, Luke, Robinson, Katherine, Roccheri, Maria Carmela, Rocchi, Stephane, Rodney, George, Rodrigues, Tiago, Rodrigues Silva, Vagner Ramon, Rodriguez, Amaia, Rodriguez-Barrueco, Ruth, Rodriguez-Henche, Nieves, Rodriguez-Rocha, Humberto, Roelofs, Jeroen, Rogers, Robert, Rogov, Vladimir, ROJO, Ana, Rolka, Krzysztof, Romanello, Vanina, Romani, Luigina, Romano, Alessandra, Romano, Patricia, Romeo-Guitart, David, Romero, Luis, Romero, Montserrat, Roney, Joseph, Rongo, Christopher, Roperto, Sante, Rosenfeldt, Mathias, Rosenstiel, Philip, Rosenwald, Anne, Roth, Kevin, Roth, Lynn, Roth, Steven, Rouschop, Kasper, Roussel, Benoit, Roux, Sophie, Rovere-Querini, Patrizia, Roy, Ajit, Rozieres, Aurore, Ruano, Diego, Rubinsztein, David, Rubtsova, Maria, Ruckdeschel, Klaus, Ruckenstuhl, Christoph, Rudolf, Emil, Rudolf, Rüdiger, Ruggieri, Alessandra, Ruparelia, Avnika Ashok, Rusmini, Paola, Russell, Ryan, Russo, Gian Luigi, Russo, Maria, Russo, Rossella, Ryabaya, Oxana, Ryan, Kevin, Ryu, Kwon-Yul, Sabater-Arcis, Maria, Sachdev, Ulka, Sacher, Michael, Sachse, Carsten, Sadhu, Abhishek, Sadoshima, Junichi, Safren, Nathaniel, Saftig, Paul, Sagona, Antonia, Sahay, Gaurav, Sahebkar, Amirhossein, Sahin, Mustafa, Sahin, Ozgur, Sahni, Sumit, Saito, Nayuta, Saito, Shigeru, Saito, Tsunenori, Sakai, Ryohei, Sakai, Yasuyoshi, Sakamaki, Jun-Ichi, Saksela, Kalle, Salazar, Gloria, Salazar-Degracia, Anna, Salekdeh, Ghasem, Saluja, Ashok, Sampaio-Marques, Belém, Sanchez, Maria Cecilia, Sanchez-Alcazar, Jose, Sanchez-Vera, Victoria, Sancho-Shimizu, Vanessa, Sanderson, J Thomas, Sandri, Marco, Santaguida, Stefano, Santambrogio, Laura, Santana, Magda, Santoni, Giorgio, Sanz, Alberto, Sanz, Pascual, Saran, Shweta, Sardiello, Marco, Sargeant, Timothy, Sarin, Apurva, Sarkar, Chinmoy, Sarkar, Sovan, Sarrias, Maria-Rosa, Sarkar, Surajit, Sarmah, Dipanka Tanu, Sarparanta, Jaakko, Sathyanarayan, Aishwarya, Sathyanarayanan, Ranganayaki, Scaglione, K Matthew, Scatozza, Francesca, Schaefer, Liliana, Schafer, Zachary, Schaible, Ulrich, Schapira, Anthony, Scharl, Michael, Schatzl, Hermann, Schein, Catherine, Scheper, Wiep, Scheuring, David, Schiaffino, Maria Vittoria, Schiappacassi, Monica, Schindl, Rainer, Schlattner, Uwe, Schmidt, Oliver, Schmitt, Roland, Schmidt, Stephen, Schmitz, Ingo, Schmukler, Eran, Schneider, Anja, Schneider, Bianca, Schober, Romana, Schoijet, Alejandra, Schott, Micah, Schramm, Michael, Schröder, Bernd, Schuh, Kai, Schüller, Christoph, Schulze, Ryan, Schürmanns, Lea, Schwamborn, Jens, Schwarten, Melanie, Scialo, Filippo, Sciarretta, Sebastiano, Scott, Melanie, Scotto, Kathleen, Scovassi, A Ivana, Scrima, Andrea, Scrivo, Aurora, Sebastian, David, Sebti, Salwa, Sedej, Simon, Segatori, Laura, Segev, Nava, Seglen, Per, Seiliez, Iban, Seki, Ekihiro, Selleck, Scott, Sellke, Frank, Selsby, Joshua, Sendtner, Michael, Senturk, Serif, Seranova, Elena, Sergi, Consolato, Serra-Moreno, Ruth, Sesaki, Hiromi, Settembre, Carmine, Setty, Subba Rao Gangi, Sgarbi, Gianluca, Sha, Ou, Shacka, John, Shah, Javeed, Shang, Dantong, Shao, Changshun, Shao, Feng, Sharbati, Soroush, Sharkey, Lisa, Sharma, Dipali, Sharma, Gaurav, Sharma, Kulbhushan, Sharma, Pawan, Sharma, Surendra, Shen, Han-Ming, Shen, Hongtao, Shen, Jiangang, Shen, Ming, Shen, Weili, Shen, Zheni, Sheng, Rui, Sheng, Zhi, Sheng, Zu-Hang, Shi, Jianjian, Shi, Xiaobing, Shi, Ying-Hong, Shiba-Fukushima, Kahori, Shieh, Jeng-Jer, Shimada, Yohta, Shimizu, Shigeomi, Shimozawa, Makoto, Shintani, Takahiro, Shoemaker, Christopher, Shojaei, Shahla, Shoji, Ikuo, Shravage, Bhupendra, Shridhar, Viji, Shu, Chih-Wen, Shu, Hong-Bing, Shui, Ke, Shukla, Arvind, Shutt, Timothy, Sica, Valentina, Siddiqui, Aleem, Sierra, Amanda, Sierra-Torre, Virginia, Signorelli, Santiago, Sil, Payel, Silva, Bruno, Silva, Johnatas, Silva-Pavez, Eduardo, Silvente-Poirot, Sandrine, Simmonds, Rachel, Simon, Anna Katharina, Simon, Hans-Uwe, Simons, Matias, Singh, Anurag, Singh, Lalit, Singh, Rajat, Singh, Shivendra, Singh, Shrawan, Singh, Sudha, Singh, Sunaina, Singh, Surinder Pal, Sinha, Debasish, Sinha, Rohit Anthony, Sinha, Sangita, Sirko, Agnieszka, Sirohi, Kapil, Sivridis, Efthimios, Skendros, Panagiotis, Skirycz, Aleksandra, Slaninová, Iva, Smaili, Soraya, Smertenko, Andrei, Smith, Matthew, Soenen, Stefaan, Sohn, Eun Jung, Sok, Sophia, Solaini, Giancarlo, Soldati, Thierry, Soleimanpour, Scott, Soler, Rosa, Solovchenko, Alexei, Somarelli, Jason, Sonawane, Avinash, Song, Fuyong, Song, Hyun Kyu, Song, Ju-Xian, Song, Kunhua, Song, Zhiyin, Soria, Leandro, Sorice, Maurizio, Soukas, Alexander, Soukup, Sandra-Fausia, Sousa, Diana, Sousa, Nadia, Spagnuolo, Paul, Spector, Stephen, Srinivas Bharath, M., St Clair, Daret, Stagni, Venturina, Staiano, Leopoldo, Stalnecker, Clint, Stankov, Metodi, Stathopulos, Peter, Stefan, Katja, Stefan, Sven Marcel, Stefanis, Leonidas, Steffan, Joan, Steinkasserer, Alexander, Stenmark, Harald, Sterneckert, Jared, Stevens, Craig, Stoka, Veronika, Storch, Stephan, Stork, Björn, Strappazzon, Flavie, Strohecker, Anne Marie, Stupack, Dwayne, Su, Huanxing, Su, Ling-Yan, Su, Longxiang, Suarez-Fontes, Ana, Subauste, Carlos, Subbian, Selvakumar, Subirada, Paula, Sudhandiran, Ganapasam, Sue, Carolyn, Sui, Xinbing, Summers, Corey, Sun, Guangchao, Sun, Jun, SUN, Kang, Sun, Meng-xiang, Sun, Qiming, Sun, Yi, Sun, Zhongjie, Sunahara, Karen, Sundberg, Eva, Susztak, Katalin, Sutovsky, Peter, Suzuki, Hidekazu, Sweeney, Gary, Symons, J David, Sze, Stephen Cho Wing, Szewczyk, Nathaniel, Tabęcka-Łonczynska, Anna, Tabolacci, Claudio, Tacke, Frank, Taegtmeyer, Heinrich, Tafani, Marco, Tagaya, Mitsuo, Tai, Haoran, Tait, Stephen, Takahashi, Yoshinori, Takats, Szabolcs, Talwar, Priti, Tam, Chit, Tam, Shing Yau, Tampellini, Davide, Tamura, Atsushi, Tan, Chong Teik, Tan, Eng-King, Tan, Ya-Qin, Tanaka, Masaki, Tanaka, Motomasa, Tang, Daolin, Tang, Jingfeng, Tang, Tie-Shan, Tanida, Isei, Tao, Zhipeng, Taouis, Mohammed, Tatenhorst, Lars, Tavernarakis, Nektarios, Taylor, Allen, Taylor, Gregory, Taylor, Joan, Tchetina, Elena, Tee, Andrew, Tegeder, Irmgard, Teis, David, Teixeira, Natercia, Teixeira-Clerc, Fatima, Tekirdag, Kumsal, Tencomnao, Tewin, Tenreiro, Sandra, Tepikin, Alexei, Testillano, Pilar, Tettamanti, Gianluca, Tharaux, Pierre-Louis, Thedieck, Kathrin, Thekkinghat, Arvind, Thellung, Stefano, Thinwa, Josephine, Thirumalaikumar, V.P., Thomas, Sufi Mary, Thomes, Paul, Thorburn, Andrew, Thukral, Lipi, Thum, Thomas, Thumm, Michael, Tian, Ling, Tichy, Ales, Till, Andreas, Timmerman, Vincent, Titorenko, Vladimir, Todi, Sokol, Todorova, Krassimira, Toivonen, Janne, Tomaipitinca, Luana, Tomar, Dhanendra, Tomas-Zapico, Cristina, Tomić, Sergej, Tong, Benjamin Chun-Kit, Tong, Chao, Tong, Xin, Tooze, Sharon, Torgersen, Maria, Torii, Satoru, Torres-López, Liliana, Torriglia, Alicia, Towers, Christina, Towns, Roberto, Toyokuni, Shinya, Trajkovic, Vladimir, Tramontano, Donatella, Tran, Quynh-Giao, Travassos, Leonardo, Trelford, Charles, Tremel, Shirley, Trougakos, Ioannis, Tsao, Betty, Tschan, Mario, Tse, Hung-Fat, Tse, Tak Fu, Tsugawa, Hitoshi, Tsvetkov, Andrey, Tumbarello, David, Tumtas, Yasin, Tuñón, María, Turcotte, Sandra, Turk, Boris, Turk, Vito, Turner, Bradley, Tuxworth, Richard, Tyler, Jessica, Tyutereva, Elena, Uchiyama, Yasuo, Ugun-Klusek, Aslihan, Uhlig, Holm, Ułamek-Kozioł, Marzena, Ulasov, Ilya, Umekawa, Midori, Ungermann, Christian, Unno, Rei, Urbe, Sylvie, Uribe-Carretero, Elisabet, Üstün, Suayib, Uversky, Vladimir, Vaccari, Thomas, Vaccaro, Maria, Vahsen, Björn, Vakifahmetoglu-Norberg, Helin, Valdor, Rut, Valente, Maria, Valko, Ayelén, Vallee, Richard, Valverde, Angela, Van Den Berghe, Greet, van der Veen, Stijn, Van Kaer, Luc, van Loosdregt, Jorg, van Wijk, Sjoerd, Vandenberghe, Wim, Vanhorebeek, Ilse, Vannier-Santos, Marcos, Vannini, Nicola, Vanrell, M Cristina, Vantaggiato, Chiara, Varano, Gabriele, Varela-Nieto, Isabel, Varga, Máté, Vasconcelos, M Helena, Vats, Somya, Vavvas, Demetrios, Vega-Naredo, Ignacio, Vega-Rubin-de-Celis, Silvia, Velasco, Guillermo, Velázquez, Ariadna, Vellai, Tibor, Vellenga, Edo, Velotti, Francesca, Verdier, Mireille, Verginis, Panayotis, Vergne, Isabelle, Verkade, Paul, Verma, Manish, Verstreken, Patrik, Vervliet, Tim, Vervoorts, Jörg, Vessoni, Alexandre, Victor, Victor, Vidal, Michel, Vidoni, Chiara, Vieira, Otilia, Vierstra, Richard, Viganó, Sonia, Vihinen, Helena, Vijayan, Vinoy, Vila, Miquel, Vilar, Marçal, Villalba, José, Villalobo, Antonio, Villarejo-Zori, Beatriz, Villarroya, Francesc, Villarroya, Joan, Vincent, Olivier, Vindis, Cecile, Viret, Christophe, Viscomi, Maria Teresa, Visnjic, Dora, Vitale, Ilio, Vocadlo, David, Voitsekhovskaja, Olga, Volonté, Cinzia, Volta, Mattia, Vomero, Marta, Von Haefen, Clarissa, Vooijs, Marc, Voos, Wolfgang, Vucicevic, Ljubica, Wade-Martins, Richard, Waguri, Satoshi, Waite, Kenrick, Wakatsuki, Shuji, Walker, David, Walker, Mark, Walker, Simon, Walter, Jochen, Wandosell, Francisco, Wang, Bo, Wang, Chao-Yung, Wang, Chen, Wang, Chenran, Wang, Chenwei, Wang, Cun-Yu, Wang, Dong, Wang, Fangyang, Wang, Feng, Wang, Fengming, Wang, Guansong, Wang, Han, Wang, Hao, Wang, Hexiang, Wang, Hong-Gang, Wang, Jianrong, Wang, Jigang, Wang, Jiou, Wang, Jundong, Wang, Kui, Wang, Lianrong, Wang, Liming, Wang, Maggie Haitian, Wang, Meiqing, Wang, Nanbu, Wang, PengWei, Wang, PeiPei, Wang, Ping, Wang, Qing Jun, Wang, Qing, Wang, Qing Kenneth, Wang, Qiong, Wang, Wen-Tao, Wang, Wuyang, Wang, Xinnan, Wang, Xuejun, Wang, Yan, Wang, Yanchang, Wang, Yanzhuang, Wang, Yen-Yun, Wang, Yihua, Wang, Yipeng, Wang, Yu, wang, yuqi, Wang, Zhe, Wang, Zhenyu, Wang, Zhouguang, Warnes, Gary, Warnsmann, Verena, Watada, Hirotaka, Watanabe, Eizo, Watchon, Maxinne, Wawrzyńska, Anna, Weaver, Timothy, Wegrzyn, Grzegorz, Wehman, Ann, Wei, Huafeng, Wei, Lei, Wei, Taotao, Wei, Yongjie, Weiergräber, Oliver, Weihl, Conrad, Weindl, Günther, Weiskirchen, Ralf, Wells, Alan, Wen, Runxia, Wen, Xin, Werner, Antonia, Weykopf, Beatrice, Wheatley, Sally, Whitton, J Lindsay, Whitworth, Alexander, Wiktorska, Katarzyna, Wildenberg, Manon, Wileman, Tom, Wilkinson, Simon, Willbold, Dieter, Williams, Brett, Williams, Robin, Williams, Roger, Williamson, Peter, Wilson, Richard, Winner, Beate, Winsor, Nathaniel, Witkin, Steven, Wodrich, Harald, Woehlbier, Ute, Wollert, Thomas, Wong, Esther, Wong, Jack Ho, Wong, Richard, Wong, Vincent Kam Wai, Wong, W Wei-Lynn, Wu, An-Guo, Wu, Chengbiao, Wu, Jian, Wu, Junfang, Wu, Kenneth, Wu, Min, Wu, Shan-Ying, Wu, Shengzhou, Wu, Shu-Yan, Wu, Shufang, Wu, William, Wu, Xiaohong, Wu, Xiaoqing, Wu, Yao-Wen, Wu, Yihua, Xavier, Ramnik, Xia, Hongguang, Xia, Lixin, Xia, Zhengyuan, Xiang, Ge, Xiang, Jin, Xiang, Mingliang, Xiang, Wei, Xiao, Bin, Xiao, Guozhi, Xiao, Hengyi, Xiao, Hong-tao, Xiao, Jian, Xiao, Lan, Xiao, Shi, Xiao, Yin, Xie, Baoming, Xie, Chuan-Ming, Xie, Min, Xie, Yuxiang, Xie, Zhiping, Xie, Zhonglin, Xilouri, Maria, Xu, Congfeng, Xu, En, Xu, Haoxing, Xu, Jing, Xu, Jinrong, Xu, Liang, Xu, Wen Wen, Xu, Xiulong, Xue, Yu, Yakhine-Diop, Sokhna, Yamaguchi, Masamitsu, Yamaguchi, Osamu, Yamamoto, Ai, Yamashina, Shunhei, Yan, Shengmin, Yan, Shian-Jang, Yan, Zhen, Yanagi, Yasuo, Yang, Chuanbin, Yang, Dun-Sheng, Yang, Huan, Yang, Huang-Tian, Yang, Hui, Yang, Jin-Ming, Yang, Jing, Yang, Jingyu, Yang, Ling, Yang, Liu, Yang, Ming, Yang, Pei-Ming, Yang, Qian, Yang, Seungwon, Yang, Shu, Yang, Shun-Fa, Yang, Wannian, Yang, Wei Yuan, Yang, Xiaoyong, Yang, Xuesong, Yang, Yi, Yang, Ying, Yao, Honghong, Yao, Shenggen, Yao, Xiaoqiang, Yao, Yong-Gang, Yao, Yong-Ming, Yasui, Takahiro, Yazdankhah, Meysam, Yen, Paul, Yi, Cong, Yin, Xiao-Ming, Yin, Yanhai, Yin, Zhangyuan, Yin, Ziyi, Ying, Meidan, Ying, Zheng, Yip, Calvin, Yiu, Stephanie Pei Tung, Yoo, Young, Yoshida, Kiyotsugu, Yoshii, Saori, Yoshimori, Tamotsu, Yousefi, Bahman, Yu, Boxuan, Yu, Haiyang, Yu, Jun, Yu, Li, Yu, Ming-Lung, Yu, Seong-Woon, Yu, Victor, Yu, W Haung, Yu, Zhengping, Yu, Zhou, Yuan, Junying, Yuan, Ling-Qing, Yuan, Shilin, Yuan, Shyng-Shiou, Yuan, Yanggang, Yuan, Zengqiang, Yue, Jianbo, Yue, Zhenyu, Yun, Jeanho, Yung, Raymond, Zacks, David, Zaffagnini, Gabriele, Zambelli, Vanessa, Zanella, Isabella, Zang, Qun, Zanivan, Sara, Zappavigna, Silvia, Zaragoza, Pilar, Zarbalis, Konstantinos, Zarebkohan, Amir, Zarrouk, Amira, Zeitlin, Scott, Zeng, Jialiu, Zeng, Ju-deng, Žerovnik, Eva, Zhan, Lixuan, Zhang, Bin, Zhang, Donna, Zhang, Hanlin, Zhang, Hong, Zhang, Honghe, Zhang, Huafeng, Zhang, Huaye, Zhang, Hui, Zhang, Hui-Ling, Zhang, Jianbin, Zhang, Jianhua, Zhang, Jing-Pu, Zhang, Kalin, Zhang, Leshuai, Zhang, Lin, Zhang, Lisheng, Zhang, Lu, Zhang, Luoying, Zhang, Menghuan, Zhang, Peng, Zhang, Sheng, Zhang, Wei, Zhang, Xiangnan, Zhang, Xiao-Wei, Zhang, Xiaolei, Zhang, Xiaoyan, Zhang, Xin, Zhang, Xinxin, Zhang, Xu Dong, Zhang, Yang, Zhang, Yanjin, Zhang, Yi, Zhang, Ying-Dong, Zhang, Yingmei, Zhang, Yuan-Yuan, Zhang, Yuchen, Zhang, Zhe, Zhang, Zhengguang, Zhang, Zhibing, Zhang, Zhihai, Zhang, Zhiyong, Zhang, Zili, Zhao, Haobin, Zhao, Lei, Zhao, Shuang, Zhao, Tongbiao, Zhao, Xiao-Fan, Zhao, Ying, Zhao, Yongchao, Zhao, Yongliang, Zhao, Yuting, Zheng, Guoping, Zheng, Kai, Zheng, Ling, Zheng, Shizhong, Zheng, Xi-Long, Zheng, Yi, Zheng, Zu-Guo, Zhivotovsky, Boris, Zhong, Qing, Zhou, Ao, Zhou, Ben, Zhou, Cefan, ZHOU, Gang, Zhou, Hao, Zhou, Hong, Zhou, Hongbo, Zhou, Jie, Zhou, Jing, Zhou, Jiyong, Zhou, Kailiang, Zhou, Rongjia, Zhou, Xu-jie, Zhou, Yanshuang, Zhou, Yinghong, Zhou, Yubin, Zhou, Zheng-Yu, Zhou, Zhou, Zhu, Binglin, Zhu, Changlian, Zhu, Guo-Qing, Zhu, Haining, Zhu, Hongxin, Zhu, Hua, Zhu, Wei-Guo, Zhu, Yanping, Zhu, Yushan, Zhuang, Haixia, Zhuang, Xiaohong, Zientara-Rytter, Katarzyna, Zimmermann, Christine, Ziviani, Elena, Zoladek, Teresa, Zong, Wei-Xing, Zorov, Dmitry, Zorzano, Antonio, Zou, Weiping, Zou, Zhen, Zou, Zhengzhi, Zuryn, Steven, Zwerschke, Werner, Brand-Saberi, Beate, Dong, X Charlie, Kenchappa, Chandra Shekar, Li, Zuguo, Lin, Yong, Oshima, Shigeru, Rong, Yueguang, Sluimer, Judith, Stallings, Christina, Tong, Chun-Kit, Ahmad, S. Tariq, Alim Al-Bari, M. Abdul, Bechara, Luiz R.G., Behrens, Georg M.N., Bhuiyan, Md. Shenuarin, Broaddus, V. Courtney, Buchan, J. Ross, Burón, M. Isabel, Carter, A. Brent, Chan, Matthew T.V., Choi, Augustine M.K., D’Adamo, Stefania, D’Amelio, Marcello, D’Arcangelo, Daniela, D’Lugos, Andrew, D’Orazi, Gabriella, De Meyer, Guido R.Y., Delpino, M. Victoria, Distler, Jörg H.W., Dixon, Ian M.C., Dobson, Renwick C.J., 2nd Dorn, Gerald, Eissa, N. Tony, Engelsen, Agnete S.T., Fairlie, W. Douglas, Ferreira, Julio C.B., H.B., Ranjitha, Hanson, Phyllis I., Hejtmancik, J. Fielding, Ho, Idy H.T., Hobbs, G. Aaron, Hoet, Peter H.M., Huang, Michael L.H., Iyer, Anand Krishnan V., Johnson, Gail V.W., Joosten, Leo A.B., Karim, Md. Razaul, Kaufmann, Stefan H.E., Ko, Ben C.B., Leck, Lionel Y.W., Lima, Thania R.R., Livingston, J. Andrew, Martin, Alexandre P.J., Montes, L. Ruth, Murphy, J. Patrick, Ng, Charlene C.W., Nicolao, M. Celeste, O’Donovan, Tracey, O’Leary, Seónadh, O’Rourke, Eyleen, O’Sullivan, Mary, O’Sullivan, Timothy, Omary, M. Bishr, Pereira, Gustavo J.S., Ratnayaka, J. Arjuna, Riazuddin, S. Amer, Rouschop, Kasper M.A., Sanderson, J. Thomas, Scaglione, K. Matthew, Schapira, Anthony H.V., Scovassi, A. Ivana, St. Clair, Daret, Sunahara, Karen K.S., Symons, J. David, Triola, Gemma, van Wijk, Sjoerd J.L., Vanrell, M. Cristina, Vasconcelos, M. Helena, Whitton, J. Lindsay, Williams, Robin S.B., Wong, W. Wei-Lynn, Wu, William K.K., Yakhine-Diop, Sokhna M.S., Yu, W. Haung, Zhang, Kalin Y.B., Dong, X. Charlie, Ain Shams University [ASU], Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University [JGU], Medical University Graz, Centre de Recherche des Cordeliers [CRC (UMR_S_1138 / U1138)], Institut Pasteur d'Iran, Leibniz Institute of Plant Biochemistry [IPB], The University of Texas M.D. Anderson Cancer Center [Houston], Institut de pharmacologie moléculaire et cellulaire [IPMC], Lipides - Nutrition - Cancer [Dijon - U1231] [LNC], Centre méditerranéen de médecine moléculaire [C3M], Institut de Biologie Valrose [IBV], Petites Molécules de neuroprotection, neurorégénération et remyélinisation, Signalisation Hormonale, Physiopathologie Endocrinienne et Métabolique, Institut Cochin [IC UM3 (UMR 8104 / U1016)], Institut NeuroMyoGène [INMG], Paris-Centre de Recherche Cardiovasculaire [PARCC (UMR_S 970/ U970)], Marqueurs cardiovasculaires en situation de stress [MASCOT (UMR_S_942 / U942)], Institut de Recherche sur le Cancer et le Vieillissement [IRCAN], Centre de Recherche en Cancérologie de Marseille [CRCM], Centre for Integrative Biology - CBI [Inserm U964 - CNRS UMR7104 - IGBMC], Oncogenesis, Stress, Signaling [OSS], Institut Necker Enfants-Malades [INEM - UM 111 (UMR 8253 / U1151)], Institut de Biologie Intégrative de la Cellule [I2BC], Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte [M2iSH], Centre de Recherches en Cancérologie de Toulouse [CRCT], Physiopathologie et traitement des maladies du foie, Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL], Institut de Génétique et de Biologie Moléculaire et Cellulaire [IGBMC], Laboratoire Bio-PeroxIL. Biochimie du peroxysome, inflammation et métabolisme lipidique [Dijon] [BIO-PEROXIL], Centre de recherche sur l'Inflammation [CRI (UMR_S_1149 / ERL_8252 / U1149)], Unité de génétique et biologie des cancers [U830], Laboratoire d'Optique et Biosciences [LOB], Institut des Maladies Métaboliques et Casdiovasculaires [UPS/Inserm U1297 - I2MC], Différenciation et communication neuronale et neuroendocrine [DC2N], Institut de Recherche en Cancérologie de Montpellier [IRCM - U1194 Inserm - UM], Centre d'Immunologie de Marseille - Luminy [CIML], Physiopathologie et imagerie des troubles neurologiques [PhIND], Laboratory of Fundamental and Applied Bioenergetics = Laboratoire de bioénergétique fondamentale et appliquée [LBFA], Imagine - Institut des maladies génétiques (IHU) [Imagine - U1163], Institut Mondor de Recherche Biomédicale [IMRB], Franco-czech Laboratory for clinical research on obesity, University of Michigan [Ann Arbor], University of Michigan System, Institut de pharmacologie moléculaire et cellulaire (IPMC), Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Université Côte d'Azur (UCA), Lipides - Nutrition - Cancer [Dijon - U1231] (LNC), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement, Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), Institut de Biologie Valrose (IBV), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Sud - Paris 11 (UP11), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université de Paris (UP), Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Nutrition, Métabolisme, Aquaculture (NuMéA), Université de Pau et des Pays de l'Adour (UPPA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut NeuroMyoGène (INMG), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Paris-Centre de Recherche Cardiovasculaire (PARCC - UMR-S U970), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), Institut de Recherche sur le Cancer et le Vieillissement (IRCAN), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Bourgogne Franche-Comté [COMUE] (UBFC), Centre de Recherche en Cancérologie de Marseille (CRCM), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Aix Marseille Université (AMU), Centre for Integrative Biology - CBI (Inserm U964 - CNRS UMR7104 - IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institute of genetics and molecular and cellular biology-Centre National de la Recherche Scientifique (CNRS), Chemistry, Oncogenesis, Stress and Signaling (COSS), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-CRLCC Eugène Marquis (CRLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Necker Enfants-Malades (INEM - UM 111 (UMR 8253 / U1151)), Unité de Nutrition Humaine (UNH), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Clermont Auvergne (UCA), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Clermont Auvergne (UCA), Institut des Maladies Neurodégénératives [Bordeaux] (IMN), Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS), Centre International de Recherche en Infectiologie - UMR (CIRI), École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherches en Cancérologie de Toulouse (CRCT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physiologie et Génomique des Poissons (LPGP), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), Laboratoire Bio-PeroxIL. Biochimie du peroxysome, inflammation et métabolisme lipidique [Dijon] (BIO-PEROXIL), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Institut Jean-Pierre Bourgin (IJPB), AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Unité de génétique et biologie des cancers (U830), Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire d'Optique et Biosciences (LOB), École polytechnique (X)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Différenciation et communication neuronale et neuroendocrine (DC2N), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Centre d'Immunologie de Marseille - Luminy (CIML), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Physiopathologie et imagerie des troubles neurologiques (PhIND), Université de Caen Normandie (UNICAEN), Laboratory of Fundamental and Applied Bioenergetics = Laboratoire de bioénergétique fondamentale et appliquée (LBFA), Université Grenoble Alpes (UGA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Epithelial biology and disease - Liliane Bettencourt Chair of Developmental Biology (Equipe Inserm U1163), Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), Biomécanique cellulaire et respiratoire (BCR), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS), Charles University [Prague]-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by the National Institute of General Medical Sciences [GM131919]., Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM), Marqueurs cardiovasculaires en situation de stress (MASCOT (UMR_S_942 / U942)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)-Université Sorbonne Paris Nord, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes (UN)-Institut National de la Recherche Agronomique (INRA), Département Plateforme (PF I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut Gustave Roussy (IGR), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Chinese Academy of Medical Sciences [Suzhou, Chine] (CAMS), Karolinska Institutet [Stockholm], Karolinska University Hospital [Stockholm], Department of Women's and Children's Health [Stockholm, Sweden], Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-École polytechnique (X), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, FHU OncoAge - Pathologies liées à l’âge [CHU Nice] (OncoAge), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA)-Institut de Pharmacologie Moléculaire et Cellulaire [UNIV Côte d'Azur] (UPMC), Institut Universitaire du Cancer de Toulouse - Oncopole (IUCT Oncopole - UMR 1037), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM), Life Sciences Institute [Ann Arbor, MI, USA], University of Michigan System-University of Michigan System, European Institute of Oncology IRCCS [Milan, Italy] (EIO), Ain Shams University (ASU), Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University (JGU), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), Réseau International des Instituts Pasteur (RIIP), Leibniz Institute of Plant Biochemistry (IPB), Hebrew University of Jerusalem, Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Agro Dijon, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Paris-Centre de Recherche Cardiovasculaire (PARCC (UMR_S 970/ U970)), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Oncogenesis, Stress, Signaling (OSS), Institut des Maladies Métaboliques et Casdiovasculaires (UPS/Inserm U1297 - I2MC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes (UGA), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Charles University [Prague] (CU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., Adamopoulos, I. E., Adeli, K., Adolph, T. E., Adornetto, A., Aflaki, E., Agam, G., Agarwal, A., Aggarwal, B. B., Agnello, M., Agostinis, P., Agrewala, J. N., Agrotis, A., Aguilar, P. V., Ahmad, S. T., Ahmed, Z. M., Ahumada-Castro, U., Aits, S., Aizawa, S., Akkoc, Y., Akoumianaki, T., Akpinar, H. A., Al-Abd, A. M., Al-Akra, L., Al-Gharaibeh, A., Alaoui-Jamali, M. A., Alberti, S., Alcocer-Gomez, E., Alessandri, C., Ali, M., Alim Al-Bari, M. A., Aliwaini, S., Alizadeh, J., Almacellas, E., Almasan, A., Alonso, A., Alonso, G. D., Altan-Bonnet, N., Altieri, D. C., Alvarez, E. M. C., Alves, S., Alves da Costa, C., Alzaharna, M. M., Amadio, M., Amantini, C., Amaral, C., Ambrosio, S., Amer, A. O., Ammanathan, V., An, Z., Andersen, S. U., Andrabi, S. A., Andrade-Silva, M., Andres, A. M., Angelini, S., Ann, D., Anozie, U. C., Ansari, M. Y., Antas, P., Antebi, A., Anton, Z., Anwar, T., Apetoh, L., Apostolova, N., Araki, T., Araki, Y., Arasaki, K., Araujo, W. L., Araya, J., Arden, C., Arevalo, M. -A., Arguelles, S., Arias, E., Arikkath, J., Arimoto, H., Ariosa, A. R., Armstrong-James, D., Arnaune-Pelloquin, L., Aroca, A., Arroyo, D. S., Arsov, I., Artero, R., Asaro, D. M. L., Aschner, M., Ashrafizadeh, M., Ashur-Fabian, O., Atanasov, A. G., Au, A. K., Auberger, P., Auner, H. W., Aurelian, L., Autelli, R., Avagliano, L., Avalos, Y., Aveic, S., Aveleira, C. A., Avin-Wittenberg, T., Aydin, Y., Ayton, S., Ayyadevara, S., Azzopardi, M., Baba, M., Backer, J. M., Backues, S. K., Bae, D. -H., Bae, O. -N., Bae, S. H., Baehrecke, E. H., Baek, A., Baek, S. -H., Baek, S. H., Bagetta, G., Bagniewska-Zadworna, A., Bai, H., Bai, J., Bai, X., Bai, Y., Bairagi, N., Baksi, S., Balbi, T., Baldari, C. 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V., Umekawa, M., Ungermann, C., Unno, R., Urbe, S., Uribe-Carretero, E., Ustun, S., Uversky, V. N., Vaccari, T., Vaccaro, M. I., Vahsen, B. F., Vakifahmetoglu-Norberg, H., Valdor, R., Valente, M. J., Valko, A., Vallee, R. B., Valverde, A. M., Van den Berghe, G., van der Veen, S., Van Kaer, L., van Loosdregt, J., van Wijk, S. J. L., Vandenberghe, W., Vanhorebeek, I., Vannier-Santos, M. A., Vannini, N., Vanrell, M. C., Vantaggiato, C., Varano, G., Varela-Nieto, I., Varga, M., Vasconcelos, M. H., Vats, S., Vavvas, D. G., Vega-Naredo, I., Vega-Rubin-de-Celis, S., Velasco, G., Velazquez, A. P., Vellai, T., Vellenga, E., Velotti, F., Verdier, M., Verginis, P., Vergne, I., Verkade, P., Verma, M., Verstreken, P., Vervliet, T., Vervoorts, J., Vessoni, A. T., Victor, V. M., Vidal, M., Vidoni, C., Vieira, O. V., Vierstra, R. D., Vigano, S., Vihinen, H., Vijayan, V., Vila, M., Vilar, M., Villalba, J. M., Villalobo, A., Villarejo-Zori, B., Villarroya, F., Villarroya, J., Vincent, O., Vindis, C., Viret, C., Viscomi, M. T., Visnjic, D., Vitale, I., Vocadlo, D. J., Voitsekhovskaja, O. V., Volonte, C., Volta, M., Vomero, M., Von Haefen, C., Vooijs, M. A., Voos, W., Vucicevic, L., Wade-Martins, R., Waguri, S., Waite, K. A., Wakatsuki, S., Walker, D. W., Walker, M. J., Walker, S. A., Walter, J., Wandosell, F. G., Wang, B., Wang, C. -Y., Wang, C., Wang, D., Wang, F., Wang, G., Wang, H., Wang, H. -G., Wang, J., Wang, K., Wang, L., Wang, M. H., Wang, M., Wang, N., Wang, P., Wang, Q. J., Wang, Q., Wang, Q. K., Wang, Q. A., Wang, W. -T., Wang, W., Wang, X., Wang, Y., Wang, Y. -Y., Wang, Z., Warnes, G., Warnsmann, V., Watada, H., Watanabe, E., Watchon, M., Wawrzynska, A., Weaver, T. E., Wegrzyn, G., Wehman, A. M., Wei, H., Wei, L., Wei, T., Wei, Y., Weiergraber, O. H., Weihl, C. C., Weindl, G., Weiskirchen, R., Wells, A., Wen, R. H., Wen, X., Werner, A., Weykopf, B., Wheatley, S. P., Whitton, J. L., Whitworth, A. J., Wiktorska, K., Wildenberg, M. E., Wileman, T., Wilkinson, S., Willbold, D., Williams, B., Williams, R. S. B., Williams, R. L., Williamson, P. R., Wilson, R. A., Winner, B., Winsor, N. J., Witkin, S. S., Wodrich, H., Woehlbier, U., Wollert, T., Wong, E., Wong, J. H., Wong, R. W., Wong, V. K. W., Wong, W. W. -L., Wu, A. -G., Wu, C., Wu, J., Wu, K. K., Wu, M., Wu, S. -Y., Wu, S., Wu, W. K. K., Wu, X., Wu, Y. -W., Wu, Y., Xavier, R. J., Xia, H., Xia, L., Xia, Z., Xiang, G., Xiang, J., Xiang, M., Xiang, W., Xiao, B., Xiao, G., Xiao, H., Xiao, H. -T., Xiao, J., Xiao, L., Xiao, S., Xiao, Y., Xie, B., Xie, C. -M., Xie, M., Xie, Y., Xie, Z., Xilouri, M., Xu, C., Xu, E., Xu, H., Xu, J., Xu, L., Xu, W. W., Xu, X., Xue, Y., Yakhine-Diop, S. M. S., Yamaguchi, M., Yamaguchi, O., Yamamoto, A., Yamashina, S., Yan, S., Yan, S. -J., Yan, Z., Yanagi, Y., Yang, C., Yang, D. -S., Yang, H., Yang, H. -T., Yang, J. -M., Yang, J., Yang, L., Yang, M., Yang, P. -M., Yang, Q., Yang, S., Yang, S. -F., Yang, W., Yang, W. Y., Yang, X., Yang, Y., Yao, H., Yao, S., Yao, X., Yao, Y. -G., Yao, Y. -M., Yasui, T., Yazdankhah, M., Yen, P. M., Yi, C., Yin, X. -M., Yin, Y., Yin, Z., Ying, M., Ying, Z., Yip, C. K., Yiu, S. P. T., Yoo, Y. H., Yoshida, K., Yoshii, S. R., Yoshimori, T., Yousefi, B., Yu, B., Yu, H., Yu, J., Yu, L., Yu, M. -L., Yu, S. -W., Yu, V. C., Yu, W. H., Yu, Z., Yuan, J., Yuan, L. -Q., Yuan, S., Yuan, S. -S. F., Yuan, Y., Yuan, Z., Yue, J., Yue, Z., Yun, J., Yung, R. L., Zacks, D. N., Zaffagnini, G., Zambelli, V. O., Zanella, I., Zang, Q. S., Zanivan, S., Zappavigna, S., Zaragoza, P., Zarbalis, K. S., Zarebkohan, A., Zarrouk, A., Zeitlin, S. O., Zeng, J., Zeng, J. -D., Zerovnik, E., Zhan, L., Zhang, B., Zhang, D. D., Zhang, H., Zhang, H. -L., Zhang, J., Zhang, J. -P., Zhang, K. Y. B., Zhang, L. W., Zhang, L., Zhang, M., Zhang, P., Zhang, S., Zhang, W., Zhang, X., Zhang, X. -W., Zhang, X. D., Zhang, Y., Zhang, Y. -D., Zhang, Y. -Y., Zhang, Z., Zhao, H., Zhao, L., Zhao, S., Zhao, T., Zhao, X. -F., Zhao, Y., Zheng, G., Zheng, K., Zheng, L., Zheng, S., Zheng, X. -L., Zheng, Y., Zheng, Z. -G., Zhivotovsky, B., Zhong, Q., Zhou, A., Zhou, B., Zhou, C., Zhou, G., Zhou, H., Zhou, J., Zhou, K., Zhou, R., Zhou, X. -J., Zhou, Y., Zhou, Z. -Y., Zhou, Z., Zhu, B., Zhu, C., Zhu, G. -Q., Zhu, H., Zhu, W. -G., Zhu, Y., Zhuang, H., Zhuang, X., Zientara-Rytter, K., Zimmermann, C. M., Ziviani, E., Zoladek, T., Zong, W. -X., Zorov, D. B., Zorzano, A., Zou, W., Zou, Z., Zuryn, S., Zwerschke, W., Brand-Saberi, B., Dong, X. C., Kenchappa, C. S., Lin, Y., Oshima, S., Rong, Y., Sluimer, J. C., Stallings, C. L., Tong, C. -K., and Centre National de la Recherche Scientifique (CNRS)
Subjects: 0301 basic medicine, Programmed cell death, Settore BIO/06, Autophagosome, Autolysosome, [SDV]Life Sciences [q-bio], lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Autophagy-Related Proteins, Review, Computational biology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, Settore MED/04, 03 medical and health sciences, stress, Chaperone-mediated autophagy, ddc:570, Autophagy, LC3, Animals, Humans, cancer, Settore BIO/10, flux, lysosome, macroautophagy, neurodegeneration, phagophore, vacuole, Set (psychology), Molecular Biology, 030102 biochemistry & molecular biology, business.industry, Interpretation (philosophy), Autophagosomes, Cell Biology, Multicellular organism, 030104 developmental biology, Knowledge base, Biological Assay, Lysosomes, business, Biomarkers, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract: Contains fulltext : 232759.pdf (Publisher’s version ) (Closed access) In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.
Published: 2021
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19. Effects of Alcoholic Extracts of Bangladeshi Mangrove Acanthus ilicifolius Linn. (Acanthaceae) Leaf and Stem on Atherogenic Model of Wistar Albino Rats

Author: Md. Sohanur Rahman, Tanjina Islam, Rubaba Karim, Md. Sahab Uddin, Ashfia Fatima Khan, Shafiul Islam Khan, Md. Tanvir Kabir, Mst. Marium Begum, and Md. Abdul Alim
Subjects: Antioxidant, Article Subject, DPPH, medicine.medical_treatment, Other systems of medicine, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Diabetes mellitus, medicine, 030304 developmental biology, 0303 health sciences, Traditional medicine, biology, medicine.diagnostic_test, business.industry, Acanthaceae, Acanthus ilicifolius, medicine.disease, biology.organism_classification, Ascorbic acid, Complementary and alternative medicine, chemistry, Simvastatin, 030220 oncology & carcinogenesis, business, Lipid profile, RZ201-999, Research Article, medicine.drug
Abstract: Acanthus ilicifolius Linn. (Acanthaceae) is a popular mangrove ethnomedicinal plant that cures several ailments, including asthma, diabetes, cancer, and many others. Our experiment was aimed at evaluating the anti-atherogenic effect of A. ilicifolius (leaf and stem) on a high-fat diet-induced atherogenic rat model. Atherosclerosis was developed in 12 weeks. Treatment with the standard drug (3 mg/kg b.w./day, p.o. of Simvastatin), separate doses of methanolic and ethanolic extracts of A. ilicifolius leaf (250 and 500 mg/kg b.w./day, p.o.), and stem (200 and 400 mg/kg b.w./day, p.o.) was subsequently conducted for additional 15 days. The anti-atherogenic effect was evaluated by estimating the change in body weight, systolic blood pressure, and lipid profile. Histopathology of aorta, liver, and kidney of atherogenic models was done for further evaluation. The antioxidant effect of different extracts was performed via DPPH (2,2-diphenyl-1-picrylhydrazyl) assay using ascorbic acid as standard. The anticoagulant effect was determined after 15 days of treatment with the same doses of the plant extracts and the standard Warfarin (2 mg/kg b.w./day, p.o.). When compared with atherogenic control, treatment with A. ilicifolius significantly reduced ( p p
Published: 2021
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20. Presence of Antibiotic-Resistant Pathogens in School Cafeteria’s Fast Foods in Dhaka City, Bangladesh: A Growing Concern

Author: Sompa Reza, Sharmin Rumi Alim, and Ila Ismail
Subjects: Salmonella, Antibiotic resistance, biology, business.industry, medicine, General Earth and Planetary Sciences, Cafeteria, biology.organism_classification, medicine.disease_cause, business, General Environmental Science, Fast foods, Biotechnology
Abstract: Burden, due to foodborne diseases, particularly Salmonella infection, is high in developing countries like Bangladesh. This research aimed at the molecular characterization of Salmonella spp., isolated from selected school canteen’s fast foods in Dhaka city, Bangladesh, and to evaluate the antibiotic resistance patterns of isolated foodborne pathogens. The school cafeterias were selected by the convenience sampling method. The samples were collected aseptically, and serial dilutions were made. The bacterial colonies were isolated by spread plate technique using appropriate media, and bacterial identification was carried out using gram staining and biochemical tests such as MIU, KIA, Oxidase, and Catalase test. The strain of Salmonella spp. was confirmed by molecular characterization employing the 16S rRNA gene sequencing method. The susceptibility of the isolates to various antibiotics was observed by modified Kirby-Bauer disk diffusion method. Most of the samples were found to contain an unacceptable level of a total aerobic count, which ranged from 5.6×105 to 6.1×107 and 3.4×104 to 7.2×107 for burger and sandwich samples, respectively. Significant isolates from the pathogenic strains were Salmonella spp., Shigella, Klebsiella, Proteus, E. coli, Vibrio spp., Clostridium spp., Staphylococcus spp., and others. The further molecular characterization of isolated Salmonella spp. suggests the similarity with Salmonella enterica serovar Rissen SeqrSC0091. Most isolates were resistant against Ampicillin (100%), Azithromycin (60.87%), Tetracycline (39.43%), Colistin (32.61%), while were highly sensitive to Gentamycin and Chloramphenicol. The presence of multidrug-resistant foodborne pathogens at this high level in the school cafeteria’s fast foods signifies an increased risk for the children’s health.
Published: 2021
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21. Screening of Salinity Tolerance of Twenty Rice Genotypes at the Seedling Stage Through Hydroponic and Ssr Marker

Author: Monir Hossain, Monirul Islam, Sharif Ahmad Al Muti, Pritish Chandra Paul, Shahidul Islam, SM Abdul Alim, Faysal Arafatbin Siddique, and Mahmud Al Noor
Subjects: Salinity, Horticulture, biology, Seedling, Genotype, General Medicine, Stage (hydrology), biology.organism_classification
Abstract: Salinity is one of the major abiotic stresses which severely affect the production of crops across the world. In this experiment, we examined 20 rice genotypes of diverse origins and sources including few salt tolerant varieties (Binadhan-8, Binadhan-10, Pokkali and FL478) as check. The main objective of this study was to determine salt tolerance at seedling stage and to evaluate genetic variation using SSR markers. IRRI standard protocol was applied to screen out salinity among those varieties, at the glasshouse of Bangladesh Institute of Nuclear Agriculture, BAU campus, Mymensingh-2202. Shoot length, root length and total dry matter were recorded at 6dS/m, 8dS/m, 10dS/m and 12 dS/m salt stress levels. According to the morphological and molecular survey of 20 rice genotypes at the seedling stage it was evident that, Binadhan-8, Binadhan-10, Pokkali, FL478, IR64, IR4630, FR13A and Sadamota identified as salt tolerant whereas THDB, Moulata, MV-20, CPD-23, CPD-29, Pot-18, Pot-27 and Dudkalam those were found as susceptible, BRRI dhan67, Binadhan-17 and Binadhan-21 those were traced as highly susceptible. The highest Nei’s genetic distance value 1.0 was found in Moulata vs Sadamota and the lowest value 0.08 was observed in Binadhan-21 vs IR64. It will be used in future breeding program to develop a saline tolerant variety of rice. Res. Agric., Livest. Fish.8(1): 75-88, April 2021
Published: 2021
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22. Effect of Administration of CHAGURO Made of Chayote (Sechium edule) and Tuna (Thunnus sp.) on Rats Induced with Streptozotocin-Nicotinamide and a High-Fat Diet

Author: Toto Sudargo, Bianda Aulia, Atika Anif Prameswari, Alim Isnansetyo, Indun Dewi Puspita, Siti Ari Budiyanti, Rahadyana Muslichah, Tira Aristasari, Sheila Rosmala Putri, and Khusnul Alfionita
Subjects: 0301 basic medicine, 030109 nutrition & dietetics, biology, business.industry, Medicine (miscellaneous), 030209 endocrinology & metabolism, Streptozotocin nicotinamide, biology.organism_classification, 03 medical and health sciences, 0302 clinical medicine, Fat diet, Medicine, Food science, Sechium, Tuna, business, Thunnus sp, human activities, Food Science
Abstract: This study was conducted to develop Chaguro, a low-cost supplementary food made of chayote (Sechium edule (Jacq.) Swartz) and tuna fish (Thunnus sp.), for diabetes and dyslipidemia diet therapy. In order to find a formula with effective hypoglycaemic and antidyslipidemic properties, dried tuna and chayote were mixed at different ratios: F1 (75% tuna, 25% chayote), F2 (50% tuna, 50% chayote), and F3 (25% tuna, 75% chayote). Thirty male Sprague Dawley rats were assigned into healthy control group or groups induced with streptozotocin-nicotinamide and a high-fat diet. Chaguro was administered 2.7 g/ kgBW/ day using a gavage for 28 days. The administration of all Chaguro formulas improved blood markers compared to the negative control group (p < 0.001). Chaguro F2 lowered fasting blood glucose (97.07±1.18 vs 266.31±5.31), total cholesterol (113.59±2.22 vs 208.78±4.31), triglycerides (89.93±2.51 vs 142.35±2.83), LDL-c (33.87±1.87 vs 87.85±3.34) and increased HDL-c (69,08±1,85 vs 23,91±1,64) level the most compared to the negative control group (p < 0.001). Streptozotocin-induced weight loss was also prevented in all diabetic rats fed with Chaguro, with the bodyweight being similar to that of healthy controls at the end of the intervention (p < 0.001). This study found that Chaguro may be a potential food product to help lower blood glucose and improve lipid profile in diabetes and dyslipidemia.
Published: 2021
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23. Replacing fishmeal with pretreated Lima bean improves growth, feed utilization, whole-body composition and nutrient retention in Nile-tilapia fingerlings

Author: Paulin Nyadjeu, Hapsatou Alim, Minette Eyango Tabi-Tomedi, Achare Elvis Ayamba, Justin Djimbie Djopnang, and Noël Arlette Tamko Ndjuissi
Subjects: Meal, Nile tilapia, Whole body composition, Fish meal, Nutrient, Ecology, biology, technology, industry, and agriculture, food and beverages, Composition (visual arts), Food science, Aquatic Science, biology.organism_classification
Abstract: The present study aimed to assess the effect of replacing fishmeal (FM) with soaked, cooked Lima bean meal (LBM) on growth, feed utilization, body composition and nutrient retention in Nile tilapia...
Published: 2021
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24. Effects of Parameters on Solvent Extraction of Oil From Sandbox (Hura Crepitans) Seed Oil Using 2^4 Factorial Design

Author: Luka Bobby Shakarau, Abdul Gambo Alim, Isaiah Kehinde Ogbobame, Samaila Yohanna Adidauki, J. D. Amine, and Owhor Sampson Chisa
Subjects: biology, Chemistry, Sandbox (computer security), Factorial experiment, Hura, Solvent extraction, Pulp and paper industry, biology.organism_classification, General Economics, Econometrics and Finance
Abstract: The present work deals with the production of biodiesel from Sandbox (Hura crepitans) seed oil and the optimization of the parameters that influence the transesterification of Sandbox (Hura crepitans)seed oil into biodiesel using Response Surface Methodology. Hura crepitans oil was obtained from by using hydraulic press for Mechanical and n-hexane for solvent extraction. Esterification was done using methanol and sodium hydroxide. A total of 48 experiments using Central Composite Design were carried out. The R-Squared, Adequate Precision, Predicted and Adjusted R-Squared values were 0.9367, 19.219, 0.8576 and 0.9070 respectively. The result of the extraction of oil, physiochemical properties, and optimization process shows that sandbox (Hura crepitans) seed oil has characteristics that are more favorable to biodiesel production. The optimal conditions for extraction of oil from sandbox seed oil were given as alcohol/ oil ratio of 5.0, catalyst amount of 20 g/ml, extraction temperature of 60 ºC, and extraction time of 45.01 minutes, with the predicted oil yield as 97.33% respectively which shows that the experimental values are in good agreement with predicted values.
Published: 2021
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25. The impact of nitrifying probiotic to population growth of pathogenic bacteria, Vibrio sp., and toxic nitrogen gasses in marine shrimp culture media under laboratory condition

Author: Bambang Widigdo, Fitriana Nazar, Inka Destiana Sapitri, Munti Yuhana, Claritha Madonsa, Yusli Wardiatno, Aliati Iswantari, and Agus Alim Hakim
Subjects: biology, Chemistry, Nitrobacter, Pathogenic bacteria, biology.organism_classification, medicine.disease_cause, Vibrio, law.invention, Shrimp farming, Probiotic, law, Nitrifying bacteria, medicine, Food science, Nitrosomonas, Bacteria
Abstract: Intensification of shrimp farming has led to problems of water quality and development of pathogenic bacteria. The excess feed and fecal deposited in the bottom of the pond undergo ammonification and result in excess of ammonia formation in pond water and sediment. The purposes of this research was to investigate the impact nitrifying bacteria application on the controlling of pathogenic Vibrio sp. bacteria and toxic nitrogen gasses. Twelve (12) transparent glass bottles (effective volume of 3 L) were used in this research. Tested probiotic was purchased in free market and producer claims to contain Nitrosomonas sp., Nitrosococcus sp., Nitrobacter sp., Bacillus sp., Aerobacter sp., and Pseudomonas sp. The tested media was sea water containing Vibrio sp., TAN, NO2 and NO3 of 54.07 ± 2.93 mg/L; 6.33 ± 0.17 mg/L; 2.43 ± 0.04 mg/L; and 0.46 ± 0.01 mg/L respectively. The treatment of probiotic was 0 mg/L as a control; 0.1 mg/L; 0.2 mg/L; and 0.4 mg/L with 3 replications. In regard to concentration of Vibrio sp., NH3 and NO2 gasses, treatment doses of 0.1 mg/L (A) resulted a save level within 4 days after treatment, but to more secure in the practical work for shrimp farm, the doses of 0.2 mg/L (B) is suggested.
Published: 2021
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26. Physico-chemical Analysis, Total Polyphenolic Content and Antioxidant Capacity of Yellow Dye Extracted from Curcuma longa

Author: Alim-un Nisa, Sajila Hina, Muhammad Khalid Saeed, Imran Kalim, Ijaz Ahmad, and Naseem Zahra
Subjects: Antioxidant, biology, medicine.medical_treatment, biology.organism_classification, Rhizome, YELLOW DYE, Antioxidant capacity, chemistry.chemical_compound, chemistry, Polyphenol, Toxicity, medicine, Curcumin, Food science, Curcuma, General Agricultural and Biological Sciences
Abstract: Turmeric (Curcuma longa) is a well known condiment of the Asian cuisine and also used as ayurvedic medicine in the content, since ancient times due to its potential therapeutic properties. Main colouring constituent of Curcuma longa is curcumin and curcuminoids. In the present work natural yellow dye was extracted from rhizome of turmeric using an effective low cost method of solvent extraction. The developed natural yellow dye was assessed for physico-chemical analysis, toxicity, polyphenolic content and antioxidant activity. Physico-chemical assay showed good nutritional profile of the extracted natural yellow dye and quite safe at dose level 3.5g/Kg body wt. Significant phenolic content was found to be 63.32 mg GAE/100g, and also showed potent antioxidant capacity (% inhibition) ranging from 5.1-20.4 at 1-5 mg/mL concentration. Animal trials showed no mortality in the mice.
Published: 2021
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27. Pharmacological Activities of Crinum viviparum: A Laboratory-based Study

Author: Liton Sikder, Mir Imran Alim, Bushra Saieda, Muhammad Torequl Islam, Shams Ara Khan, Javad Sharifi-Rad, and Miquel Martorell
Subjects: Pharmacology, 010404 medicinal & biomolecular chemistry, Complementary and alternative medicine, Traditional medicine, 010405 organic chemistry, Phytochemical composition, Crinum, Biology, biology.organism_classification, 01 natural sciences, 0104 chemical sciences
Abstract: The phytochemical composition of the ethanolic extract of Crinum viviparum was determined and the anti-bacterial, anti-inflammatory, thrombolytic, and anti-diarrheal activities were investigated by...
Published: 2021
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28. New Class of Chitosanase from Bacillus amyloliquefaciens for the Generation of Chitooligosaccharides

Author: Bhoopal Bhuvanachandra, Sk Alim, Samudrala Rambabu, Gopi Preethiba, Musti J. Swamy, Appa Rao Podile, and D. Sivaramakrishna
Subjects: Bacillus amyloliquefaciens, biology, Chemistry, fungi, technology, industry, and agriculture, Isothermal titration calorimetry, macromolecular substances, General Chemistry, equipment and supplies, biology.organism_classification, carbohydrates (lipids), Chitosan, chemistry.chemical_compound, Differential scanning calorimetry, Chitin, Chitosanase, General Agricultural and Biological Sciences, Nuclear chemistry
Abstract: Chitooligosaccharides (COS) generated from either chitin (chitin oligosaccharides) or chitosan (chitosan oligosaccharides) have a wide range of applications in agriculture, medicine, and other fiel...
Published: 2021
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29. Purification and some properties of fungal Xylanase

Author: Nabil Abu Al Qasim, Saeed Mansour, Marwa Abdul Aziz, and Yasser Abdul Al-Alim
Subjects: chemistry.chemical_classification, Ammonium sulfate, biology, Strain (chemistry), Aspergillus niger, Substrate (chemistry), biology.organism_classification, Xylan, chemistry.chemical_compound, Enzyme, chemistry, Xylanase, Acetone, Nuclear chemistry
Abstract: Partial purification of xylanase produced by Aspergillus niger strain AUMC 14230 is carried out with 80% saturation of ammonium sulfate under pH5.0 as first step. The second step in partial purification is Acetone 2.5/1 (v/v). The last step is gill filtrations which give the highest specific from both enzymes. Many factors affecting on purified enzymes. The best activity of xylanase was produced till 72 hrs and decreased by (8.8% & 10.9%), respectively after 72 hrs. Xylan (1mg) concentration was the best substrate to produce relative activity 100% for xylanase enzyme. We found that the glucose has an inhibitory effect on both enzymes activity. Optimum temperature for xylanase is 50oC, increased temperature decreased productivity of both enzymes. The addition of Ca2+, Ba2+, Mg2+ and EDTA strongly enhanced both xylanase activity, While, Co2+ and Ag+ decreased the productivity. On the other hand, the Fe2+, Cu2+ and Mn2+ showed moderate inhibition.
Published: 2021
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30. Meat origin differentiation by polymerase chain reaction-restriction fragment length polymorphism

Author: Ariful Islam, Salah Uddin, Anjuman Ara Bhuyan, Asad Ud-Daula, Mridha Kamal Hossain, Atm Mijanur Rahman, Joyanta Halder, Abdul Alim, Nusrat Jahan, M. Mahmud Hasan, Rubaya, and Jahangir Alam
Subjects: Genetics, meat identification, mitochondrial 12s rrna, Nutrition. Foods and food supply, food and beverages, differentiation, Biology, TP368-456, Food processing and manufacture, law.invention, law, Identification (biology), TX341-641, pcr-rflp, Restriction fragment length polymorphism, Animal species, Polymerase chain reaction, Food Science
Abstract: Identification of meat and meat products is significant for economic, religious, or public health reasons. This study focused on the detection and differentiation of meat animal species. A total of sixty-four meat samples (10 samples of each like beef, buffen, chevon, and mutton; twenty-four samples of pork) were analyzed for these purposes. PCR-RFLP of 12S rRNA gene with four restriction enzymes was performed on individual meat samples as well as mixture of different meat. Species specific primers as well as sequencing of DNA were also used to detect and verify the RFLP results. PCR amplification yielded a 456bp fragments from 100% samples. AluI digested beef DNA into 359 and 97bp, chevon and mutton DNA into 246 and 210bp fragments and pork DNA into 290 and 166bp fragments. However, it cannot digest buffen DNA. On the other hand HhaI digested only buffen DNA into 247 and 209bp fragments but not others. ApoI restricts only mutton DNA and yielded 329 and 127bp fragments but not others. Nevertheless, BspTI yielded 323 and 133bp fragments only from chevon. Besides, mixed samples (1:1) of beef-buffen and chevon-mutton can be differentiated by AluI & HhaI and BspTI & ApoI, respectively. Chord analysis based on our sequence and respective sequences of studied animals from GenBank indicated that the cutting sites are conserved in these species of animals. Phylogenetically each of the species was clustered separately. This technique may be useful for meat animal species detection and differentiation either from individual meat and mixed meat samples.
Published: 2021

31. Metabolomic profiling to reveal the therapeutic potency of Posidonia oceanica nanoparticles in diabetic rats

Author: Mona A. Mohammed, Ahmed Serag, Heba Elmotasem, Abdel-Hamid Z. Abdel-Hamid, Abdel Nasser El Gendy, Sameh Hosam Abd El-Alim, Mansour Sobeh, Mohamed A. El Raey, Naglaa M. Ammar, and Heba A. Hassan
Subjects: 0303 health sciences, Antioxidant, food.ingredient, biology, Chemistry, General Chemical Engineering, medicine.medical_treatment, Insulin, Glucose transporter, General Chemistry, Metabolism, biology.organism_classification, Gelatin, 03 medical and health sciences, 0302 clinical medicine, food, Metabolomics, Biochemistry, In vivo, Posidonia oceanica, medicine, 030217 neurology & neurosurgery, 030304 developmental biology
Abstract: Posidonia oceanica is a sea grass belonging to the family Posidoniaceae, which stands out as a substantial reservoir of bioactive compounds. In this study, the secondary metabolites of the P. oceanica rhizome were annotated using UPLC-HRESI-MS/MS, revealing 86 compounds including simple phenolic acids, flavonoids, and their sulphated conjugates. Moreover, the P. oceanica butanol extract exhibited substantial antioxidant and antidiabetic effects in vitro. Thus, a reliable, robust drug delivery system was developed through the encapsulation of P. oceanica extract in gelatin nanoparticles to protect active constituents, control their release and enhance their therapeutic activity. To confirm these achievements, untargeted GC-MS metabolomics analysis together with biochemical evaluation was employed to investigate the in vivo anti-diabetic potential of the P. oceanica nano-extract. The results of this study demonstrated that the P. oceanica gelatin nanoparticle formulation reduced the serum fasting blood glucose level significantly (p < 0.05) in addition to improving the insulin level, together with the elevation of glucose transporter 4 levels. Besides, multivariate/univariate analyses of the GC-MS metabolomic dataset revealed several dysregulated metabolites in diabetic rats, which were restored to normalized levels after treatment with the P. oceanica gelatin nanoparticle formulation. These metabolites mainly originate from the metabolism of amino acids, fatty acids and carbohydrates, indicating that this type of delivery was more effective than the plain extract in regulating these altered metabolic processes. Overall, this study provides novel insight for the potential of P. oceanica butanol extract encapsulated in gelatin nanoparticles as a promising and effective antidiabetic therapy.
Published: 2021
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32. Comparison of Morphological Characters of Freshwater Crayfish (Cherax quadricarinatus) from Different Ecosystems in Indonesia

Author: Agus Alim Hakim, Iya Purnama Sari, Ali Mashar, Yusli Wardiatno, and Bambang Widigdo
Subjects: Fishery, Geography, biology, Habitat, Extant taxon, Cherax quadricarinatus, Ecosystem, Carapace, biology.organism_classification, Crayfish, Crustacean, Invasive species
Abstract: Freshwater crayfish (Cherax quadricarinatus) as an invasive species has high capability to adapt in most waters in Indonesia. The extant distribution of this species in Indonesia causes observation of morphological charactersÃÂ is important to be established. This study purpose is to compare the morphological characters of Cherax quadricarinatus from several locations in Indonesia waters, such as the river in Bintan Island, Toba Lake, and Lido Lake. The total of morphological characters was measured in twenty-two characters. The result of the Kruskal-Wallis test represented nine different characters between Toba, Bintan, and Lido. Cluster analysis illustrated the highest level of similarities between Toba and Lido. The growth rate of the dactyls, and carapace width, and ocular carapace length between Toba and Lido were similar, meanwhile between Toba and Bintan were different. C. quadricarinatus originating from river waters in Bintan Island has a different morphological character from Lake Lido and Lake Toba. The differences in morphological characters between locations are caused by differences in habitat characteristics in rivers and lakes.
Published: 2020
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33. Therapeutic and Mechanistic Approaches of Tridax Procumbens Flavonoids for the Treatment of Osteoporosis

Author: Abdullah Al Mamun, Showna Hossain, Abdul Alim Al-Bari, and Ujjal Mia
Subjects: Pharmacology, Bone mineral, biology, business.industry, Clinical Biochemistry, Osteoporosis, Tridax procumbens, Osteoblast, medicine.disease, Bioinformatics, biology.organism_classification, 030226 pharmacology & pharmacy, Bone remodeling, Resorption, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Osteoclast, 030220 oncology & carcinogenesis, Rheumatoid arthritis, Drug Discovery, medicine, Molecular Medicine, business
Abstract: Homeostasis of bone is closely regulated by the balanced activities between the bone resorbing activity of osteoclast cells and bone-forming ability of osteoblast cells. Multinucleated osteoclasts degrade bone matrix and involve in the dynamic bone remodelling in coordination with osteoblasts. Disruption of this regulatory balance between these cells or any imbalance in bone remodelling caused by a higher rate of resorption over construction of bone results in a decrease of bone matrix including bone mineral density (BMD). These osteoclast-dominant effects result in a higher risk of bone crack and joint demolition in several bone-related diseases, including osteoporosis and rheumatoid arthritis (RA). Tridax procumbens is a very interesting perennial plant and its secondary metabolites called here T. procumbens flavonoids (TPFs) are well‐known phytochemical agents owing to various therapeutic practices such as anti-inflammatory, anti-anaemic and anti-diabetic actions. This review designed to focus the systematic convention concerning the medicinal property and mechanism of actions of TPFs for the management of bone-related diseases. Based on the current literature, the review offers evidence-based information of TPFs for basic researchers and clinicians for the prevention and treatment of bone related diseases, including osteoporosis. It also emphasizes the medical significance for more research to comprehend the cellular signalling pathways of TPFs for the regulation of bone remodelling and discusses the possible promising ethnobotanical resource that can convey the preclinical and clinical clues to develop the next generation therapeutic agents for the treatment of bonerelated disorders.
Published: 2020
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34. Intraspecific Phenotypic Variation in Nearly Threatened Mottled Nandus, Nandus nandus (Hamilton, 1822)

Author: Sarower-E-Mahfuj, Fee Faysal Ahmed, Md. Abdul Alim, Yosni Bakar, M. A. Samad, and Simon Kumar Das
Subjects: Morphometrics, Phenotypic plasticity, education.field_of_study, In situ conservation, Multidisciplinary, Dendrogram, Population, Zoology, Biology, biology.organism_classification, Intraspecific competition, Nandus, education, Meristics
Abstract: Understanding intraspecific phenotypic plasticity is a prerequisite of stock identification, evolutionary studies, sustainable utilization, and fishery conservation. In this study, intraspecific phenotypic plasticity was assessed in terms of the external features (i.e. meristic, morphometric, and truss-based morphometrics) of the wild Nandus populations from four freshwater sources in Southwestern Bangladesh. Fish samples were collected from Arial Kha River, Madaripur (AKRM, n=26); Nabaganga River, Jhenaidah (NRJ, n=22); Bohnni Baor, Gopalganj (BBG, n=26); and Dhakuria Beel, Jashore (DBJ, n=22). Meristic, morphometric, and truss network data were subjected to one-way ANOVA followed by post hoc (Tukey-HSD) test. The meristic counts of all the samples demonstrated significant differences only in one of the six characters. By contrast, significant differences were observed in 8 morphometric characters and 31 truss network data from 16 morphometric characters and 35 truss network data, respectively. Principal component (PCA) and canonical variate analyses (CVA) were also performed on morphometric and truss-based network data. Meristic and morphometric results from PCA and CVA showed that populations were completely intermingled, forming a compact cluster within intrapopulation levels, while truss morphometric characters formed a separate cluster. Three dendrograms independently based on phenotypic relationships among the individuals of the four populations also confirmed the absence of phenotypic differentiation among the population due to clustering of different groups. The baseline information resulting from the current study would be useful for genetic studies and further in situ conservation of Nandus populations in Bangladesh.
Published: 2020
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35. Bangladeş, Chattogram, Sandwip Adası'ndaki Koyun ve Keçilerde Gastrointestinal Parazit Enfeksiyonlarının Prevalansı

Author: Abdul Alim, Sonnet Poddar, Mohammad Amir Hossen, Md. Abdullah Al Mamun, Mohammad Alamgir Hossain, Mrinmoy Bhowmik, and Farazi Muhammad Yasir Hasib
Subjects: Veterinary medicine, medicine.medical_specialty, Veterinary, Epidemiology, Prevalence, medicine, Veteriner Hekimlik, Helminths, General Medicine, Biology, Gastrointestinal paraziter enfeksiyon,keçi,prevalans,koyun, Gastrointestinal parasitic infection,goat,prevalence,sheep
Abstract: Gastrointestinal (GI) parasitic infection is considered a common problem in sheep and goat production in Bangladesh. The current investigation was undertaken to determine the prevalence of GI parasitic infection and its associated risk factors (e.g., age, sex, nutritional & deworming status etc.) in sheep and goats of the Sandwip Island, Chattogram, Bangladesh. A total of 330 faecal samples of which 220 sheep and 110 goats were taken using a random sampling method. All the samples were subjected to routine coproscopy (e.g., direct smear, flotation and sedimentation) to detect the eggs/oocysts of helminths and protozoan parasites. Results demonstrated that the overall prevalence of GI parasitic infections was 68.64% in sheep and 61.82% in goats. The frequency of nematodes and trematodes was higher in comparison to cestodes and protozoan infections in both sheep and goats of all the three study areas. Age-specific prevalence demonstrated that adult goats had significantly higher GI parasitic infections in comparison to the young population. Female sheep were more prone to GI parasitic infections whereas the opposite trend was noticed for goats. The sheep and goats having the ‘poor’ body condition score/nutritional status were more susceptible to parasitic infections compared to moderate and good health conditions. Rarely or non-dewormed sheep and goats also harboured more GI parasites compared ‘dewormed animals’. The current investigation was fresh of its types in the study areas, therefore, we recommended extensive studies including epidemiological and molecular approaches to identify GI parasitic diseases and their associated risk factors., Gastrointestinal (GI) parazit enfeksiyonu, Bangladeş'te koyun ve keçi yetiştiriciliğinde yaygın bir sorun olarak kabul edilmektedir. Mevcut araştırma, Bangladeş'in Chattogram yöresindeki Sandwip Adası koyun ve keçilerinde GI parazit enfeksiyon prevalansını ve ilişkili risk faktörlerini (örneğin, yaş, cinsiyet, beslenme ve parazitlerden arındırma durumu vb.) belirlemek için yapıldı. Rastgele örnekleme yöntemiyle 220 koyun ve 110 keçi olmak üzere toplam 330 dışkı örneği alınmıştır. Helmintlerin ve protozoan parazitlerin yumurtalarını / ookistlerini tespit etmek için tüm numuneler rutin dışkı muayenesine (örn., Doğrudan yayma, yüzdürme ve sedimantasyon) tabi tutulmuştur. Sonuçlar, GI paraziter enfeksiyonların genel prevalansının koyunlarda %68.64 ve keçilerde %61.82 olduğunu göstermiştir. Nematod ve trematod prevalansı, üç çalışma alanının her ikisinde de hem koyun hem de keçilerde sestod ve protozoan enfeksiyonlarına kıyasla daha yüksek bulunmuştur. Yetişkin keçiler, genç popülasyona kıyasla önemli ölçüde daha yüksek GI parazit enfeksiyonları göstermiştir. Dişi koyunlar GI parazit enfeksiyonlarına daha yatkın olmasına rağmen, keçilerde bunun tersi bir eğilim tespit edildi. Vücut kondisyon puanı / beslenme durumu kötü olan koyun ve keçiler, orta ve iyi sağlık koşullarına göre paraziter enfeksiyonlara daha duyarlı olduğu belirlendi. Nadiren arındırılmış ya da parazitlerden arındırılmamış koyun ve keçiler, "parazitlerden arındırılmış hayvanlara" kıyasla daha fazla GI paraziti barındırdığı ortaya konmuştur. Mevcut araştırma, çalışma alanlarında tespit edilen türler bakımından ilkdir, bu nedenle, GI paraziter hastalıkları ve bunlarla ilişkili risk faktörlerini tanımlamak için epidemiyolojik ve moleküler yaklaşımları içeren kapsamlı çalışmaların yapılması önerilmektedir.
Published: 2020
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36. Screening thirty soybean genotypes under solid and intercropping plantings in Egypt

Author: Sherif Ibrahim Abdel-Wahab, Tamer Ibrahim Abdel-Wahab, Abd El-Alim A. Metwally, S.A. Safina, and Eman Ibrahim Abdel-Wahab
Subjects: 0106 biological sciences, biology, business.industry, Field experiment, fungi, Randomized block design, food and beverages, Sowing, Intercropping, 04 agricultural and veterinary sciences, Plant Science, biology.organism_classification, 01 natural sciences, Point of delivery, Agronomy, Agriculture, Yield (wine), 040103 agronomy & agriculture, 0401 agriculture, forestry, and fisheries, business, Agronomy and Crop Science, Cropping, 010606 plant biology & botany, Biotechnology
Abstract: Cropping systems are relatively more important for testing soybean genotypes under Egyptian conditions. A field experiment was carried out at the Agricultural Experiments and Research Station, Faculty of Agriculture, Cairo University, Giza, Egypt, during the 2016 and 2017 seasons to evaluate the productivity of thirty soybean genotypes collected from four countries in intercropping with corn. Intercropping two soybean ridges alternating with another two of corn (2:2) was used in a split plot distributed in randomized complete block design. Intercropping and solid systems were randomly assigned to the main plots, and the soybean genotypes were allocated in sub-plots. All over the genotypes, intercropping caused significant increases in maturity date, root length, and plant height; meanwhile, the reverse was true for each of total leaf chlorophyll content, numbers of branches and pods, as well as seed yield per plant. Soybean genotypes Giza 111, C1, Woodworth, C34, Hill, Hutcheson, and Holladay gave higher seed yield than the others. Allover cropping systems, soybean genotypes Giza 111, Woodworth, Hutcheson, and C1 had higher seed yield than the others under intercropping. A significant positive correlation was detected between pod number and seed yield under cropping systems. Early maturing genotypes under intercropping were correlated positively with a higher yield of plants, as well as relative values. Determinate soybean variety Woodworth was matured under intercropping and solid planting at the same time. Soybean genotypes Woodworth, C1, C34, Giza 35, Giza 82, and Giza 111 were tolerant than the others to intercropping. The six soybean genotypes offer useful genetic materials for soybean breeding programs to improve yield under intercropping.
Published: 2020
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37. Effect of Weeding and Herbicide Management on Fibre Yield and Yield Attributes of Tossa Jute

Author: Hossain, MA Alim, J Ferdous, and MM Islam
Subjects: Animal science, biology, Yield (wine), Digitaria sanguinalis, General Medicine, biology.organism_classification, Mathematics, Cyperus rotundus
Abstract: The experiment was conducted at Jute Agriculture Experimental Station (JAES), Manikganj and Jute Research Regional Station, Faridpur during 2019 to find out the effect of weeding and herbicide management on fibre yield and yield attributes of Tossa jute (Var. O-9897) cultivation. Two herbicide treatments, such as; W1 = Fenoxaprop-p-ethyl (Whip Super 9 EC) and W2 = Ethoxysulfuron (Sunrice ® 150WG) were tested. There were 14 treatments. T1- T6 treatments did not include hand weeding which was done 20 days after the herbicide spray [T1 = 100% recommended doses (RD) of both W1and W2 where W2 was sprayed one day after that of W1, T 2 = 50% dose both of W1and W2 where W2 was sprayed one day after that of W1, T3 = 100% dose of both W1 and W2 where both of the herbicide mixed together and sprayed on the same day, T4 = 50% dose of both W1 and W2 where mixture of both were sprayed on the same day, T5 = only 100% dose of W1, T6 = only 100% dose of W2]. The treatments T7 - T12 included one had weeding following the application of herbicides [T7 = 100% dose both of W1 and W2 where W2 was sprayed 1 day after that of W1, T8 = 50% dose both of W1 and W2 where W2 was sprayed 1 day after of W1, T9 = 100% dose both of W1 and W2 were mixed and sprayed together on the same day, T10 = 50% dose both of W1 and W2 mixed together and sprayed same day, T11 = only 100% dose of W1, T12 = only 100% dose of W2]. The treatments T13 and T14 did not include herbicide application [T13 = Two hand weeding (20-25 and 45-50 DAS) and T14 = control with no herbicide application]. The experiment was laid out in RCBD with three replications. Results revealed that Khudesama (Echinochloa colonum) and Angulighash (Digitaria sanguinalis), Khudesama and Mutha (Cyperus rotundus) were best controlled by herbicide application. T3 gave highest fibre yield of 1.89 tha-1 when W1 and W2 sprayed at the same day with 100% RD. In case of one weeding 20 days after spray fibre yield and stick yield were differed significantly as compared to those of control at Manikganj. Treatment T7 gave highest fibre yield (3.11 t ha-1) when W2 sprayed after 1 day of W1 with 100% RD. At Faridpur, T3 gave the highest fibre yield (2.68 t ha-1) when W1 and W2 sprayed at the same day with 100% RD. Incase of one weeding 20 days after spray, T7 gave highest fiber yield (2.79 t ha-1) when W2 was sprayed 1 day after that of W1 with 100% RD. Bangladesh Agron. J. 2020, 23(1): 101-106
Published: 2020
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38. Effect of lime coating and molybdenum on the yield and nutrient uptake of green gram (Vigna radiata L.) under mid central table land zone of Odisha

Author: Meenakhi Prusty, Debashish Swain, Monika Ray, and MA Alim
Subjects: biology, Soil test, Kharif crop, Randomized block design, engineering.material, biology.organism_classification, Vigna, chemistry.chemical_compound, Horticulture, Nutrient, chemistry, Seed treatment, engineering, Fertilizer, Lime, Mathematics
Abstract: The field experiment was carried out at Regional Research and Technology Transfer Station (OUAT), Mahisapat of Dhenkanal district during kharif season of 2017 and 2018 to study the response of lime coating and molybdenum influencing the yield and nutrient uptake of green gram under Mid Central Tale Land zone of Odisha. The experiment was laid out in a randomized block design with four replications comprising of six treatments. The detailed of the treatments are as follows. T1-Soil Test Based Fertilizer Recommendation (STBFR), T2- Soil Test Based Fertilizer Recommendation (STBFR) + Rhizobium inoculation@ 20gkg-1 of seed + PSB @4 kgha-1, T3- Soil Test Based Fertilizer Recommendation (STBFR) + Rhizobium inoculation@ 20gkg-1 of seed + PSB @4 kgha-1 + FYM @5 tha-1, T4- Soil Test Based Fertilizer Recommendation (STBFR) + Rhizobium inoculation@ 20g kg-1 of seed + PSB @4 kg ha-1 + FYM @5 t ha-1 +Lime 0.2 LR, T5- Soil Test Based Fertilizer Recommendation (STBFR) + Rhizobium inoculation@ 20g kg-1 of seed + PSB @4 kgha-1 + FYM @5 tha-1 + seed coating with lime, T6- Soil Test Based Fertilizer Recommendation (STBFR) + Rhizobium inoculation@ 20gkg-1 of seed + PSB @4 kgha-1 + FYM @5 tha-1 + Molybdenum (1g Ammonium Molybdate per 2.5 kg of seed as seed treatment) + seed coating with lime. It was revealed that T6 recorded significantly higher seed yield (877.50 kg ha-1), 1000 seed weight (37.93 g) and No. of seeds per pod (12.43) followed by T5 with seed yield (827.50 kg ha-1), 1000 seed weight (37.58 g) and no. of seeds per pod (8.92). T6 was superior over T1 with the yield advantage of 34.5 % and B: C (1.76). The Concentration of nutrient N,P,K in the harvested seed was also found highest in T6 i.e. 5.27 %, 0.51% and 1.53 % followed by T5 having concentration of 5.07%,0.47 % and 1.47 % respectively. The same treatment T6 recorded higher uptake of N, P and K with 35.35, 6.62 and 20.47 kg ha-1 in the harvested seed, respectively.
Published: 2020
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39. The Effect Of Bacillus Subtilis On The Bacterial Content In Rabbits Caeci

Author: G. A. Abdel-Alim and Eman F. Farag
Subjects: Inhibition zone, Serial dilution, c. perfringens, Veterinary medicine, rabbit, caeci, Antibacterial effect, Bacillus subtilis, e. coli, law.invention, Probiotic, law, Antimicrobial effect, SF600-1100, Food science, Intestinal juice, b. subtilis, biology, Chemistry, QP501-801, biology.organism_classification, Animal biochemistry, In vitro, probiotics, QL1-991, Zoology
Abstract: In the present study, the effect of B. subtilis (107cfu/gm) supplemented to the basal diet of two groups of New Zealand rabbit of 28 days (n=15/group) on the count of commensal microflora ( Bifidobacteria and Lactobacilli spp.) and some opportunistic pathogens (E. coli and C. perfringens type A) in the rabbit caeci was investigated. Results indicated that the count of Bifidobacteria and Lactobacilli spp. are significantly increased at all intervals (7, 14, 28 and 40 days post supplementation) in the supplemented group compared with non-supplemented group with P< 0.001. On the other hand, there is a significant decrease in the count of E. coli and C. perfringens specially at 40 days post supplementation from (5.8 log 10 cfu ±0.06) to (3.1 log 10 cfu ±0.07) and from (4.8 log 10 cfu ±0.09) to (2.3 log 10 cfu ±0.09) respectively with P< 0.001. B. subtilis proved to be tolerant to the simulated gastric and intestinal juice for one hour (100% tolerance). However, after two hours, the tolerance to the gastric juice decreased to 70%, with no effect of the artificial intestinal juice on the viability of the organism. In vitro, the antimicrobial effect of B. subtilis on C. perfringens type A by well diffusion method showed an inhibition zone of 10 mm. Results of in vitro effect of B. subtilis on C. perfringens count showed that at 103 dilutions of C. perfringens, its count was reduced 2.1×105 to 3×104 after adding B. subtilis, while at dilution of 102, the count was reduced from 2.4×105 to 7×103cfu/ml after adding B. subtilis. It could be concluded that B. subtilis can be used as a probiotic in rabbits ration due to its ability to increase the commensal microflora count beside its antibacterial effect against some opportunistic pathogens.
Published: 2020
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40. Detection of Toxoplasma gondii infection among diabetic patients in Turkey

Author: Mehtap Alim, Necati Ozpinar, and Semra Özçelik
Subjects: Microbiology (medical), endocrine system diseases, Epidemiology, 03 medical and health sciences, 0302 clinical medicine, parasitic diseases, medicine, Outpatient clinic, Seroprevalence, In patient, 030212 general & internal medicine, Patient group, Elisa method, 030219 obstetrics & reproductive medicine, biology, business.industry, Public Health, Environmental and Occupational Health, nutritional and metabolic diseases, Type 2 Diabetes Mellitus, Toxoplasma gondii, biology.organism_classification, medicine.disease, Toxoplasmosis, Infectious Diseases, Immunology, business
Abstract: Backgound In some recent studies, it has been suggested that there may be a relationship between Toxoplasma gondii (T. gondii) and type 2 diabetes mellitus (T2DM). T. gondii is of greater significance in these patients. Objectives In the present study, it was aimed to investigate the seroprevalence of T. gondii in T2DM patients. Methods To define Toxoplasma IgG and IgM seropositivity and determine the seroprevalence of toxoplasmosis in patients presenting at the Internal Diseases outpatient clinic of the Healthcare Application and Research Hospital, where the ELISA method was used. 200 T2DM patients and 100 healthy individuals with no complaints took part in the study. Results Toxoplasma IgG positivity was determined in 53% of the 200 T2DM patients and Toxoplasma IgM positivity in 13%. While in the control group, Toxoplasma IgG positivity was determined in 27% and Toxoplasma IgM positivity in 1%. The risk of toxoplasmosis infection in T2DM patients was two folds higher than healthy controls according to the IgG results. IgM results were further differentiated. Conclusions We believe that the seroprevalence of T. gondii is high in the T2DM patient group and that the causes should be investigated in more detail.
Published: 2020
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41. Increased susceptibility to Mycobacterium tuberculosis infection in a diet-induced murine model of type 2 diabetes

Author: Natkunam Ketheesan, Mohammad Abdul Alim, Suchandan Sikder, Andreas Kupz, Catherine M. Rush, and Brenda Govan
Subjects: 0301 basic medicine, Tuberculosis, endocrine system diseases, medicine.medical_treatment, 030106 microbiology, Immunology, Comorbidity, Type 2 diabetes, Microbiology, Mycobacterium tuberculosis, Mice, 03 medical and health sciences, Immune system, Phagocytosis, Diabetes mellitus, medicine, Animals, Macrophage, Risk factor, Inflammation, biology, Macrophages, nutritional and metabolic diseases, medicine.disease, biology.organism_classification, Bacterial Load, Diet, Survival Rate, Disease Models, Animal, 030104 developmental biology, Infectious Diseases, Cytokine, Diabetes Mellitus, Type 2, Cytokines, Disease Susceptibility, human activities
Abstract: Tuberculosis (TB)-type 2 diabetes mellitus (T2D) comorbidity is re-emerging as a global public health problem. T2D is a major risk factor for increased susceptibility to TB infection and reactivation leading to higher morbidity and mortality. The pathophysiological mechanisms of T2D contributing to TB susceptibility are not fully understood, but likely involve dysregulated immune responses. In this study, a diet-induced murine model that reflects the cardinal features of human T2D was used to assess the immune responses following an intravenous Mycobacterium tuberculosis (Mtb) infection. In this study, T2D significantly increased mortality, organ bacillary burden and inflammatory lesions compared to non-diabetic controls. Organ-specific pro-inflammatory cytokine responses were dysregulated as early as one day post-infection in T2D mice. Macrophages derived from T2D mice showed reduced bacterial internalization and killing capacity. An early impairment of antimycobacterial functions of macrophages in diabetes is a key mechanism that leads to increased susceptibility of T2D.
Published: 2020
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42. Separation, Purification and Identification of Excellent Yeasts from the Natural Fermented Beverage of Boza

Author: Reheman Aila, Ainaitula Mahemuti, Aygul Alim, and Abulimiti kelimu
Subjects: biology, Chemistry, education, Saccharomyces cerevisiae, Identification (biology), Fermentation, Food science, Yeast strain, biology.organism_classification, humanities, Yeast
Abstract: In this study, 40 yeasts were separated and purified from five Boza samples collected in five different areas of Xinjiang Uyghur Autonomous Region. By adopting traditional morphology observation, preliminary identification, physiological and biochemical experiment, 16 excellent strains with stable fermentation characteristics were obtained, and they were confirmed with the molecular biology identification. Final results show that 12 excellent yeast strains belong to Saccharomyces cerevisiae, one excellent yeast strain belongs to Pichiamembranifaciens, and one excellent yeast strain belongs to Pichifermentans.
Published: 2020
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43. Consumption of two whole kiwifruit (Actinide chinensis) per day improves lipid homeostasis, fatty acid metabolism and gut microbiota in healthy rats

Author: Tanzeela Nisar, Xingbin Yang, Daoyuan Ren, Yueyue Liu, Aamina Alim, and Ting Li
Subjects: Male, Actinidia chinensis, Firmicutes, Actinidia, 02 engineering and technology, Gut flora, digestive system, Biochemistry, Antioxidants, Gas Chromatography-Mass Spectrometry, Rats, Sprague-Dawley, Lipid peroxidation, 03 medical and health sciences, chemistry.chemical_compound, Functional Food, Structural Biology, Malondialdehyde, Lactobacillus, Animals, Food science, Molecular Biology, 030304 developmental biology, chemistry.chemical_classification, Glutathione Peroxidase, 0303 health sciences, biology, Fatty acid metabolism, Plant Extracts, Superoxide Dismutase, Chemistry, Body Weight, Fatty Acids, Polyphenols, General Medicine, Lipid Metabolism, 021001 nanoscience & nanotechnology, biology.organism_classification, Animal Feed, Gastrointestinal Microbiome, Rats, Liver, Fruit, 0210 nano-technology, Lipoprotein, Polyunsaturated fatty acid
Abstract: Golden kiwifruit (Actinidia chinensis) peel is a by-product enriched with polyphenols. The effects of fleshes of two Actinidia chinensis fruits (ACF) and fleshes with peels of two Actinidia chinensis fruits (ACFP) on lipid homeostasis, fatty acid metabolism and gut microbiota was investigated in healthy rats. Intervention of ACF and ACFP for 4 weeks significantly reduced total cholesterol, total triglycerides, and increased the high-density lipoprotein levels in rats. ACF and ACFP ameliorated lipid peroxidation in rats, by the lowering hepatic MDA level and enhancing GSH-Px and SOD activities. In addition, ACFP significantly decreased the saturated fatty acids in serum and increased the polyunsaturated fatty acids in hepatic and serum of rats. Analysis of gut microbiota revealed that ACF and ACFP evidently increased the microbial richness and diversity of gut microbiota. The Firmicutes/Bacteroidetes ratio was significantly reduced from 3.04 in ND group to 1.34 and 2.12 in ACF and ACFP groups, respectively. Moreover, ACF and ACFP significantly increased the abundance of beneficial bacteria (Lactobacillus and Barnesiella) and reduced harmful bacteria (Enterococcus, Escherichia, and Staphylococcus). Overall, ACFP exerts more potent health-improving effects than ACF. Our study provides a scientific basis for the development of kiwifruit (including pericarp)-based novel natural products with significant health benefits.
Published: 2020
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44. The effect of treated apical periodontitis before heart valve surgery on C‐reactive protein levels

Author: Cengiz Köksal, Emir Cantürk, Betul Aycan Alim, and UYSAL, BETÜL AYCAN
Subjects: medicine.medical_specialty, Valve surgery, Disease, Gastroenterology, Endodontics, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Apical Periodontitis, medicine, Humans, Heart valve, Antibiotic prophylaxis, General Dentistry, Periodontitis, biology, business.industry, Dental infections, C-reactive protein, 030206 dentistry, medicine.disease, Heart Valves, Oral Inflammation, C-Reactive Protein, Alim B. A. , Canturk E., Köksal C., -The Effect of Treated Apical Periodontitis Before Heart Valve Surgery on C‐Reactive Protein Levels-, Oral Diseases, no.0, 2020, medicine.anatomical_structure, Otorhinolaryngology, 030220 oncology & carcinogenesis, biology.protein, Cytokines, business, Periapical Periodontitis
Abstract: ObjectiveDental infections produce significant increases in systemic inflammatory responses manifested by cytokines and acute phase reactants. This study evaluated the postoperative C‐reactive protein (CRP) levels according to patients having teeth treated or not treated for apical periodontitis (AP) before heart valve surgery.Materials and MethodsPreoperative, postoperative third‐ and fifth‐day CRP levels, and the previous dental data of 91 patients were investigated. Whether the patients had been treated for AP and whether they used antibiotic prophylaxis for this treatment were determined by examining the previous data. The analysis of covariance (ANCOVA) was used for statistical analysis.ResultsThere were no statistically significant differences in the preoperative CRP levels and the third‐day CRP levels between all patients treated and those not treated for AP (p>0.05). The mean fifth‐day CRP levels of the patients with teeth treated for AP were significantly lower than those of the patients with teeth not treated for AP (p
Published: 2020
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45. Formulation of Full Instant Functional Drinking Making With Coffee Addition

Author: Dodyk Pranowo, Claudia i Gadizza Perdan, and Alim Budiarto
Subjects: chemistry.chemical_compound, biology, Traditional medicine, chemistry, Randomized block design, Alpinia officinarum, biology.organism_classification, Sugar, Caffeine, Mathematics, Rhizome, Instant
Abstract: Galangal (Alpinia officinarum) is a type of rhizome plant such as ginger. Utilization of galangal which is still well known by the public is a spice in cooking and as a traditional herbal medicine that has not yet attracted people's interest. Further processing needs to be done to attract the public so that they can benefit from galangal. The study was designed using a Randomized Block Design (RCBD) using 2 factors. Comparison of coffee and galangal are 9: 1, 7: 3, 5: 5, and factor 2 for 50 grams of sugar, 100 grams, and 150 grams. The research results obtained by the panelists the most important formulation is the ratio of galangal and coffee 7: 3 with the approval of 150 grams of coconut sugar. The results of the antioxidant activity test obtained data about instant galangal functional drinks having antioxidant content of IC50 8.10 mg/ml have not been approved as functional drinks. The results of the caffeine content test showed that instant galangal functional drinks had caffeine levels of 2.63 ± 0.04%
Published: 2020
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46. Identification of Maize Downy Mildew Pathogen in Lampung and the Effects of Varieties and Metalaxyl on Disease Incidence

Author: Erisa Setyowati, Damar Indah Ryska Chafisa, Ambos Harry Zuisent Pasaribu, Paul Benyamin Timotiwu, Joko Prasetyo, Cipta Ginting, Tri Maryono, Alim Asyifa, Ivayani, Widyastuti, and Suskandini Ratih Dirmawati
Subjects: 0106 biological sciences, biology, Significant difference, 04 agricultural and veterinary sciences, biology.organism_classification, 01 natural sciences, General Biochemistry, Genetics and Molecular Biology, chemistry.chemical_compound, Horticulture, chemistry, Seed treatment, 040103 agronomy & agriculture, Peronosclerospora sorghi, 0401 agriculture, forestry, and fisheries, Downy mildew, General Agricultural and Biological Sciences, Metalaxyl, Pathogen, 010606 plant biology & botany
Abstract: Introduction: Maize downy mildew (MDM) is considered as a major problem in all maize growing areas in Indonesia including the Province of Lampung. Objectives: The objectives of this study were (i) to identify the species of Peronosclerospora causing maize downy mildew (MDM) in Lampung, (ii) to determine the influence of varieties on the intensity of downy mildew and (iii) to determine the efficacy of metalaxyl to control MDM on some maize varieties. Methodology: To identify Peronosclerospora causing MDM, the pathogens were observed under light microscope and scanning electron microscope. Maize varieties response against pathogens and efficacy metalaxyl were studied in the field with the test plants exposed to plants showing MDM symptoms as the sources of inocula to mimic natural conditions. Results: Peronosclerospora sorghi, P. maydis, and P. philippinensis were found to cause MDM in Lampung. On both varieties Pioneer 27 (P-27) and NK-22, AUDPC on F1 plants was greater than that on F2 plants. On P-27, the production of F2 was higher than that of F1 plants, but there was not significant difference in production between F1 and F2 of NK-22 variety. Seed treatment using metalaxyl was not effective to control downy mildew of maize. Conclusion: Three species of Peronosclerospora were identified as disease-causing pathogen of MDM in Lampung, but these results were tentatively pending for further studies through molecular techniques. F1 plants were more susceptible than F2 plants to MDM in both P-27 and NK-22. Metalaxyl was not effective in controlling MDM.
Published: 2020
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47. Influence of Water Stress on Morphology, Physiology and Yield Contributing Characteristics of Rice

Author: A Husna, S Sultana, S. Sikder, A Alim, Samina Akhter, J. C. Joardar, and MZ Hossain
Subjects: Yield (engineering), Morphology (linguistics), Agronomy, Water stress, Biology, Industrial and Manufacturing Engineering
Abstract: Water stress or drought is one of the main reasons behind the lower productivity of rice–a widely popular nutritious cereal crop and the staple food for a large portion of the world’s population. A pot experiment was conducted to investigate the effect of water stress on three rice varieties e.g. Banglamoti, Vittiatash and Atash balam in a silty clay soil. To identify whether less water affects rice production, rice plants were cultivated under five different water treatments, T1: flooding at 5 cm depth, T2: flooding at 3 cm depth, T3: saturated water condition, T4: water content@75% saturation, and T5: water content @50% saturation, and were arranged in a completely randomized design with three replications. Morphology, yield and physiological parameters of the rice plants were evaluated. Treatment below saturation did not produce any yield for all the rice varieties studied. All the morphological parameters and yields (e.g. dry weight of plants, plant height, tiller number, panicle number, grain number, grain weight, 1000 seed weight, and harvest index) showed a lower value under water deficient condition. Relative water content and water use efficiency declined with declining water content which represented the variations in their physiological responses to water stress. The grain content per panicle as well as 1000 grain weight of the rice varieties was maximum at saturation condition. Highest harvest index was observed for Vittiatash rice variety at saturated condition. Flooding the soil with either 5 cm or 3 cm depth did not produce any significant change in the studied parameters which indicated that approximately 2 cm water can easily be curtailed which may not affect the production of rice. SAARC J. Agri., 18(1): 61-71 (2020)
Published: 2020
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48. Effects of Supplementation with Furikake Ulvamina Made of Algae (Ulva sp.) and Tuna (Thunnini) on Cognitive Function of Malnourished Mice (Rattus norvegicus)

Author: Toto Sudargo, Alim Isnansetyo, Indun Dewi Puspita, Rahadyana Muslichah, Tira Aristasari, Sheila Rosmala Putri, Siti Ari Budiyanti, Khusnul Alfionita, and Yosephin Anandati Pranoto
Subjects: 0303 health sciences, 03 medical and health sciences, 0302 clinical medicine, Algae, 030309 nutrition & dietetics, food and beverages, Medicine (miscellaneous), Food science, Biology, Tuna, biology.organism_classification, 030217 neurology & neurosurgery, Food Science
Abstract: Algae (Ulva sp.) and tuna (Thunnini) are edible marine resources rich in protein, essential amino acids, zinc, and iodine that can be used to improve the growth of malnourished children including their cognitive functions. The combination of both resources may produce a supplementation (Furikake Ulvamina) with nutritional quality to support the acceleration of cognitive functions of malnourished children. This study aimed to develop a marine-based product/supplement to accelerate cognitive functions in malnourished mice (Rattus norvegicus). A product called “Furikake Ulvamina” was used in an experimental study of 25 malnourished mice. The Morris Water Maze test was adapted into a “speed time to survive” to test the cognitive functions of each group. One-way Anova tests were performed to statistically analyze the mean differences in the speed of time to survive before and after the intervention. All five groups showed an increase in the speed of time to survive after treatment was given with an average increase of speed of 26.9 seconds. Statistically, there was no significant difference in this cognitive function acceleration indicator between groups (p>0.05). Furthermore, weight and length were also increased after four weeks in all groups. There was no significant difference in cognitive function acceleration in each group of mice after the supplementation of Furikake Ulvamina for four weeks. This product may potentially accelerate growth in malnourished mice. Furikake Ulvamina can also promote the consumption and benefits of Indonesian marine local commodities (algae and tuna).
Published: 2020
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49. Production of Secondary Metabolite Compounds of Gotu Kola (Centella asiatica) Under Salinity and Drought Stress

Author: Diah Ratnadewi, Nur Amallia, and Zainal Alim Mas’ud
Subjects: chemistry.chemical_classification, Centella, biology, Abiotic stress, food and beverages, Biomass, Secondary metabolite, biology.organism_classification, High-performance liquid chromatography, Field capacity, Salinity, Triterpene, chemistry, medicine, Food science, medicine.drug
Abstract: Gotu kola (Centella asiatica) is a traditional herbal plant that has been reported have a variety of pharmacological activities. The compounds of gotu kola that play a role on pharmacological activities are triterpene group compounds, namely madecasosside (MD), asiaticoside (AS), madecassic acid (AM), and asiatic acid (AA). Stress can affect the production of biomass and secondary metabolite compounds in plants. The aims of the study is to analyze the effect of salinity and drought stress on biomass and 4 compounds of triterpene in gotu kola. Harvesting is done when the plant is 8 weeks old. The yield of the biomass was analyzed and then extracted using methanol solvent to be analyzed secondary metabolite levels using the high performance liquid chromatography (HPLC) method. The lowest crop biomass was obtained at 50% of field capacity and 3,000 ppm salt content. The highest levels of MD and AS were established in conditions of 100% field capacity and 1,000 ppm salt content. The 50 and 100% field capacity and 1,000-3,000 ppm salt content did not affect the levels of AM and AA.
Published: 2020
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50. Genotyping of κ-casein and β-lactoglobulin genes in native cattle from Barishal region of Bangladesh

Author: Anjuman Ara Bhuyan, Salma Akter, A. K. M. Mostafa Anower, Jahangir Alam, Md. Abdul Alim, Nusrat Jahan, Md. Salimullah, and M. M. Kamal Hossain
Subjects: 0301 basic medicine, Genetics, 0402 animal and dairy science, Genetic variants, food and beverages, Bioengineering, 04 agricultural and veterinary sciences, Biology, 040201 dairy & animal science, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, chemistry, Casein, Genotype, Animal Science and Zoology, Gene, Genotyping, DNA, Biotechnology
Abstract: The study was conducted to determine the genetic variants of κ-casein and β-lactoglobulin genes in native cattle. DNA was extracted from blood samples (n = 80) collected from Babuganj, Barishal fol...
Published: 2020
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