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Your search keyword '"Ketner, Rodney J."' showing total 2 results
Start Over Author "Ketner, Rodney J." Topic biological sciences
2 results on '"Ketner, Rodney J."'

1. Acid-catalyzed breakdown of alkoxide and thiolate ion adducts of benzylidene meldrum's acid, methoxybenzylidene meldrum's acid and thiomethoxybenzylidene meldrum's acid

Author

Bernasconi, Claude F., Ketner, Rodney J., Brown, Shoshana D., Chen, Xin, and Rappoport, Zvi

Subjects
Chemistry, Organic -- Research, Acids -- Research, Thiols -- Research, Biological sciences, Chemistry
Abstract

A study of the acid-catalyzed loss of alkoxide and thiolate ions from alkoxide and thiolate ion adducts is presented. The acid-catalyzed breakdown of the intermediate toward products and reactants has been analyzed.

Published
1999

2. Large steric effect in the substitution reaction of amines with phosphoimidazolide-activated nucleosides

Author

Kanavarioti, Anastassia, Stronach, Michael W., Ketner, Rodney J., and Hurley, T. Brian

Subjects
Substitution reactions -- Analysis, Amines -- Research, Nucleosides -- Analysis, Organophosphorus compounds -- Analysis, Biological sciences, Chemistry
Abstract

Kinetic studies of the reaction of different aliphatic amines with phosphoimidazolide-activated of guanosine and cytidine (ImPN) derivatives reveal that kinetic barrier for the reaction increases with the size of the alkyl group in the aliphatic secondary amines. Kinetic data support the higher reactivity of the primary amino groups than the secondary amino groups toward ImPN. The slow reactivity accounts for the absence of substitution products of the secondary amino groups of the polyamines.

Published
1995

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