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Microarray technology allows the simultaneous monitoring of expression levels of thousands of genes and even whole genomes. But the experiments themselves represent only the opening act. The grand finale, so [...]

With the ever-increasing density of microarrays comes a need for more sensitive and high-throughput ways to read the resulting data. Arrays contain tens of thousands of 50- to 150-µm-diameter spots [...]

Microarray density continues to climb. In the past year, several companies have compressed the entire protein-coding portion of the human genome onto a single chip--that's some 30,000 to 40,000 unique [...]

Australia's Monash University recently purchased the world's largest parallel protein purification workstation: a 12-module AKTAxpress system from Amersham Biosciences of Piscataway, NJ, a subsidiary of GE Healthcare. The system can [...]

Munich-based ibidi (Integrated BioDiagnostics, www.ibidi.de) has developed a line of disposable plastic perfusion slides, called g-Slides, that enable both culturing and high-resolution microscopy of live cells. Cells immobilized in a [...]

In releasing its DualChip microarray system, Eppendorf (www.eppendorf.com) of Hamburg, Germany, has blurred the lines between cDNA and oligonucleotide probes. The system makes use of Eppendorf's Xmer probes, single-stranded DNAs [...]

Sunnyvale, Calif.-based TeleChem International (www.arrayit.com) is launching the most inexpensive microarray scanner to date. Preproduction models of the 10-µm-resolution, $18,500 (US) scanner, called SpotLight, are expected to be ready at [...]

A human embryonic stem cell starter panel that allows for the in vitro expansion of human ESCs is now available from Minneapolis-based R&D Systems (www.rndsystems.com). The kit contains human FGF [...]

Applied Biosystems (www.appliedbiosystems.com), based in Foster City, Calif., has introduced a new family of reagents for multiplexed LC/MS experiments. The iTRAQ reagents enable comparison of protein expression in multiple samples, [...]

Compared to gene and protein data, which involve relatively simple sequences, the diverse nature of data characterizing brain activity is, well, mind-boggling. Data can range from functional magnetic resonance images [...]

Put a piece of DNA on a clean, DNAase-free piece of glass, and it will probably still be there in its original state hours later. Proteins, though, are much less [...]