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Your search keyword '"M. A. Iradyan"' showing total 13 results
Start Over Author "M. A. Iradyan" Topic biological activity
13 results on '"M. A. Iradyan"'

1. Synthesis and biological activity of substituted 6-alkyl(6H)-3-phenyl-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines

Author

G. M. Stepanyan, N. S. Iradyan, R. V. Paronikyan, and M. A. Iradyan

Subjects
Pharmacology, chemistry.chemical_classification, chemistry, Ionization, Drug Discovery, Pharmacology toxicology, Mass spectrum, Organic chemistry, Biological activity, Antibacterial activity, Alkyl, Electron ionization
Abstract

A series of substituted 6-alkyl(6H)-3-phenyl-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazines have been synthesized by reaction of 3-alkyl-4-amino-5-thio-1,2,4-triazoles with substituted phenacylbromides in the presence of an equimolar amount of KOH. Mass spectra for the dissociative ionization by electron impact, antibacterial activity, and antitumor properties of the synthesized compounds have been studied. It was established that some compounds at doses of 50 – 100 mg/kg decrease the growth of sarcomas 45 and 37 by 35 – 47%.

Published
2010

2. [Untitled]

Author

N. S. Iradyan, F. G. Arsenyan, G. A. Darbinyan, G. M. Stepanyan, B. T. Garibdzhanyan, E. V. Kazaryan, M. A. Iradyan, and G. M. Paronikyan

Subjects
Pharmacology, chemistry.chemical_compound, Nitroimidazole, Chemistry, Drug Discovery, Pharmacology toxicology, Imidazole, Organic chemistry, Biological activity
Published
2003

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