Author: "Titkova, A. M." / Topic: biogenic amines - Searchworks@Jio Institute Digital Library Search Results

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Start Over Author "Titkova, A. M." Topic biogenic amines

Author: Titkova AM, Pan IR, and Epstein OI
Subjects: Animals, Dopamine metabolism, Epinephrine metabolism, Male, Norepinephrine blood, Norepinephrine metabolism, Rats, Substance Withdrawal Syndrome drug therapy, Tryptophan blood, Tyrosine blood, Antibodies pharmacology, Biogenic Amines metabolism, Brain drug effects, Brain metabolism, Ethanol toxicity, Lipid Peroxidation drug effects, S100 Proteins immunology
Abstract: Antibodies against S100 protein in ultralow doses specifically affected catecholamine metabolism in rats withdrawn from chronic ethanol exposure. The contents of tryptophan, tyrosine, and norepinephrine in brain structures returned to normal. The concentrations of dopamine, epinephrine, and norepinephrine in the peripheral blood decreased. Modulation of monoamine content in the peripheral blood suggests that antibodies against S100 protein possess stress-protective activity during ethanol withdrawal.
Published: 2003
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Author: Titkova AM, Kharitonova SM, Pan IR, and Epstein OI
Subjects: Animals, Catecholamines metabolism, Hypothalamus metabolism, Morphine immunology, Morphine Dependence, Rats, Antibodies pharmacology, Biogenic Amines metabolism, Lipid Peroxidation drug effects, Morphine antagonists & inhibitors
Abstract: The efficiency of potentiated antibodies against morphine was studied on the model of chronic morphine intoxication. Test antibodies stimulated catecholamine metabolism in the hypothalamus (i.e., prevented initiation of catecholamine- and histaminergic peripheral reactions) and normalized lipid peroxidation.
Published: 2003
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