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Start Over You searched for: Author "Marzia Perluigi" Remove constraint Author: "Marzia Perluigi" Topic biochemistry Remove constraint Topic: biochemistry
85 results on '"Marzia Perluigi"'

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1. Intranasal Administration of KYCCSRK Peptide Rescues Brain Insulin Signaling Activation and Reduces Alzheimer’s Disease-like Neuropathology in a Mouse Model for Down Syndrome

2. mTOR in Alzheimer disease and its earlier stages: Links to oxidative damage in the progression of this dementing disorder

4. CAPE and its synthetic derivative VP961 restore BACH1/NRF2 axis in Down Syndrome

8. Insulin resistance, oxidative stress and mitochondrial defects in Ts65dn mice brain: a harmful synergistic path in down syndrome

9. Increased basal antioxidant levels in RCAN1 - deficient mice lowers oxidative injury after acute paraquat insult

10. BVR-A deficiency leads to autophagy impairment through the dysregulation of AMPK/mTOR axis in the brain—Implications for neurodegeneration

11. Proteomics Study of Peripheral Blood Mononuclear Cells in Down Syndrome Children

12. The Interplay Among Oxidative Stress, Brain Insulin Resistance and AMPK Dysfunction Contribute to Neurodegeneration in Type 2 Diabetes and Alzheimer Disease

13. Restoration of aberrant mTOR signaling by intranasal rapamycin reduces oxidative damage: Focus on HNE-modified proteins in a mouse model of down syndrome

14. Impairment of biliverdin reductase-A promotes brain insulin resistance in Alzheimer disease: A new paradigm

15. Redox proteomic analysis of serum from aortic anerurysm patients: insights on oxidation of specific protein target

16. Redox Proteomics: A Key Tool for New Insights into Protein Modification with Relevance to Disease

17. Oxidative Stress Links Brain Insulin Resistance and Mitochondrial Defects in Down Syndrome Brain Early in Life: Implication for Neurodegeneration

18. The BACH1/Nrf2 Axis in Brain in Down Syndrome and Transition to Alzheimer Disease-Like Neuropathology and Dementia

19. Protein nitration profile of CD3+ lymphocytes from Alzheimer disease patients: Novel hints on immunosenescence and biomarker detection

20. Disturbance of redox homeostasis in down syndrome: role of iron dysmetabolism

21. Redox control of viral carcinogenesis: The human papillomavirus paradigm

22. Evaluation of a LC–MS method for everolimus preclinical determination in brain by using [13C2D4]RAD001 internal standard

23. Down syndrome: From development to adult life to Alzheimer disease

24. The triangle of death in Alzheimer's disease brain: the aberrant cross-talk among energy metabolism, mammalian target of rapamycin signaling, and protein homeostasis revealed by redox proteomics

25. Redox proteomics analysis to decipher the neurobiology of Alzheimer-like neurodegeneration: overlaps in Down's syndrome and Alzheimer's disease brain

26. Oxidative Stress and Proteostasis Network: Culprit and Casualty of Alzheimer’s-Like Neurodegeneration

27. Redox proteomics and the dynamic molecular landscape of the aging brain

28. Intranasal rapamycin protects against cognitive decline in a mouse model of Down syndrome

29. Antisense directed against PS-1 gene decreases brain oxidative markers in aged senescence accelerated mice (SAMP8) and reverses learning and memory impairment: A proteomics study

30. HNE-modified proteins in Down syndrome: Involvement in development of Alzheimer disease neuropathology

31. Polyubiquitinylation Profile in Down Syndrome Brain Before and After the Development of Alzheimer Neuropathology

32. Oxidative stress, protein modification and Alzheimer disease

33. It Is All about (U)biquitin: Role of Altered Ubiquitin-Proteasome System and UCHL1 in Alzheimer Disease

34. Increased mammalian target of rapamycin signaling contributes to the accumulation of protein oxidative damage in a mouse model of down's syndrome

35. Sex differences in brain proteomes of neuron‐specific STAT3‐null mice after cerebral ischemia/reperfusion

36. Circulating biomarkers of protein oxidation for Alzheimer disease: Expectations within limits

37. Oxidative and Nitrosative Modifications of Biliverdin Reductase-A in the Brain of Subjects with Alzheimer's Disease and Amnestic Mild Cognitive Impairment

38. Quantitative proteomics analysis of phosphorylated proteins in the hippocampus of Alzheimer's disease subjects

39. Oxidative Damage in Rat Brain During Aging: Interplay Between Energy and Metabolic Key Target Proteins

40. Protein Oxidation and Lipid Peroxidation in Brain of Subjects with Alzheimer's Disease: Insights into Mechanism of Neurodegeneration from Redox Proteomics

41. Redox proteomics identification of oxidatively modified proteins in Alzheimer's disease brain and in vivo and in vitro models of AD centered around Aβ(1–42)☆

42. In vivo protection of synaptosomes by ferulic acid ethyl ester (FAEE) from oxidative stress mediated by 2,2-azobis(2-amidino-propane)dihydrochloride (AAPH) or Fe2+/H2O2: Insight into mechanisms of neuroprotection and relevance to oxidative stress-related neurodegenerative disorders

43. Heme oxygenase and cyclooxygenase in the central nervous system: A functional interplay

44. Proteomic Analysis of Protein Expression and Oxidative Modification in R6/2 Transgenic Mice

45. Improvement of BVR-A Activity Ameliorates Brain Insulin Resistance in Alzheimer Disease Following Intranasal Insulin Administration

46. Tyrosinase protects human melanocytes from ROS-generating compounds

47. Developmental expression and dysregulation of miR146a and miR155 in Down's syndrome and mouse models of Down's syndrome and Alzheimer's disease

48. Crosstalk between insulin resistance and oxidative stress in the development of Alzheimer-like neurodegeneration

49. Altered protein O-GlcNAcylation profile revealed by proteomics: Novel insights on protein signalling mechanisms in AD

50. Alteration of mTOR signaling occurs early in the progression of Alzheimer disease (AD): analysis of brain from subjects with pre-clinical AD, amnestic mild cognitive impairment and late-stage AD

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