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1. Luteal function in sheep with ovarian autotransplants given concurrent infusions of prolactin and prostaglandin F2 alpha into the ovarian artery

Author

J.R. Goding, J.C. Cerini, and W.A. Chamley

Subjects
endocrine system, medicine.medical_specialty, Radioimmunoassay, Prostaglandin, Ovary, Luteal phase, Ovarian artery, Biochemistry, Transplantation, Autologous, chemistry.chemical_compound, Endocrinology, medicine.artery, Internal medicine, medicine, Animals, Progesterone, Sheep, business.industry, Arteries, Prolactin, medicine.anatomical_structure, chemistry, Regional Blood Flow, Depression, Chemical, Prostaglandins, Female, business
Abstract

Four experimental sheep with ovarian autotransplants were infused with prolactin (10 or 100 μg/h), into the ovarian artery, for 6 hours and then prolactin together with prostaglandin F2α (PGF2α) (5 μg/h) for a further 6 hours. A control sheep received PGF2α alone, for 6 hours on two separate occasions. Prolactin failed to overcome the luteolytic action of PGF2α in 3 of the 4 experimental sheep.

Published
1973

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