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Your search keyword '"Aydın F"' showing total 5 results
Start Over Author "Aydın F" Topic biochemistry
5 results on '"Aydın F"'

1. Frequency and pattern of test utilization rate in clinical biochemistry laboratory: two different large hospital examples

Author

Yalçındağ Ali, Aydın Fevzi Nuri, Işıklar Özben Özden, Can Fatmagül, Karademir Murat, Uzunal Ersen, Akyurek A. Ozen, Yücel Doğan, and Serdar Muhittin A.

Subjects
test ordering, frequency of laboratory testing, outpatients, inpatients, clinical biochemistry laboratory, Biochemistry, QD415-436
Abstract

Clinical biochemistry laboratories (CBL) are the most frequently utilized laboratory group in healthcare, and their significance in patient care is indisputable. This study investigated the frequency and pattern of test utilization rate in CBL at two large hospitals’ outpatient and inpatient clinics.

Published
2024
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2. Inflammation parameters, monocyte subgroups and toll-like receptor expression before and after dialysis in patients with chronic kidney disease

Author

Kivanc Demet, Savran Oguz Fatma, Senturk Ciftci Hayriye, Aydin Filiz, and Sever Mehmet Sukru

Subjects
chronic kidney disease, dialysis, inflammation, monocyte, toll like receptors, tumor necrosis factor, Biochemistry, QD415-436
Abstract

The data of the monocyte subgroups and expressed toll like receptors (TLR) in the innate immune system response, which develop against chronic inflammation in patients with predialysis chronic kidney disease (CKD) and in patients who undergo dialysis treatment, are limited. We aimed to investigate the effect of the dialysis procedure on the current chronic inflammatory condition and which role of monocyte subgroups ratios, the expressions of TLR2/4 and serum Tumor necrosis factor alpha (TNF-α) levels involved in the innate immune response process.

Published
2022
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3. HLA DRB1 alleles, IFN-γ and TGF-β Gene Variants in childhood ALL patients

Author

Oguz Suleyman Rustu, Senturk Ciftci Hayriye, Gokce Muge, Ogret Yeliz, Kivanc Demet, Ozdilli Kursat, Atay Avni, Savran Oguz Fatma, and Aydin Filiz

Subjects
acute lymphoblastic leukemia, agvhd, cytokine, genetic polymorphism, hla, Biochemistry, QD415-436
Abstract

Graft-versus-host disease (GvHD) is a complex clinical syndrome with organ dysfunction as a consequence of a severe immunological reaction mediated by mainly T cells after hematopoietic stem cell transplantation. Our aim is to evaluate the association of HLA-DRB1 alleles, IFN-γ and TGF-β gene variations, with childhood ALL (c-ALL) patients and with GvHD after transplantation.

Published
2022
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4. Distribution of HLA epitope frequencies in Turkish population

Author

Oguz Fatma Savran, Oguz Suleyman Rustu, Ogret Yeliz, Karadeniz Tanju Sedat, Ciftci Hayriye Senturk, Karatas Sule, Kivanc Demet, and Aydin Filiz

Subjects
allele, epitope, eplet matching, hla, transplantation, epitop, transplantasyon, eplet eşleştirme, alel, Biochemistry, QD415-436
Abstract

The antibodies interact with the “Human Leukocyte Antigen (HLA) antigens” at specific epitopes. “Epitopes” are present on a single HLA or shared by multiple antigens. In this study, we aim to determine the frequency of prevalent epitopes common in the Turkish population.

Published
2022
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5. Carnosine treatment diminished oxidative stress and glycation products in serum and tissues of D-galactose-treated rats

Author

Müjdat Uysal, Canan Kucukgergin, Semra Doğru-Abbasoğlu, Esra Betül Kalaz, Fatih Aydın, Jale Çoban, Aydın, F., Kalaz, E.B., Küçükgergin, C., Çoban, J., Doğru-Abbasoğlu, S., Uysal, M., and Yeditepe Üniversitesi

Subjects
Pulmonary and Respiratory Medicine, Glycation End Products, Advanced, Male, medicine.medical_specialty, Aging, Antioxidant, medicine.medical_treatment, Carnosine, medicine.disease_cause, Antioxidants, Protein Carbonylation, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Lipid oxidation, D-Galactose, Glycation, Internal medicine, Malondialdehyde, medicine, Animals, Rats, Wistar, Advanced glycation end products, chemistry.chemical_classification, Reactive oxygen species, Age Factors, Galactose, Brain, Oxidative Stress, Endocrinology, chemistry, Biochemistry, Advanced Oxidation Protein Products, Liver, Oxidative stress, 030220 oncology & carcinogenesis, Pediatrics, Perinatology and Child Health, Lipid Peroxidation, Reactive Oxygen Species, 030217 neurology & neurosurgery, Biomarkers
Abstract

Background: Chronic administration of D-galactose (GAL) induces changes that resemble natural aging in rodents. Oxidative stress and Advanced Glycation End products (AGE) formation play a role in GAL-induced aging. Carnosine (CAR;ß-alanyl-L-histidine) has antioxidant and anti-glycating actions and may be a potential therapeutic agent in aging due to these properties. The effect of CAR supplementation on AGE levels and oxidative stress parameters was investigated in serum, liver and brain tissues in GAL-treated rats. Methods: GAL (300 mg/kg; s.c.; 5 days per week) alone or together with CAR (250 mg/kg/daily; i.p.; 5 days per week) was applied to male rats for two months. AGE, Advanced Oxidized Protein Products (AOPP), Protein Carbonyl (PC) and Malondialdehyde (MDA) levels together with Reactive Oxygen Species (ROS) formation and Ferric Reducing Antioxidant Power (FRAP) values were determined. Results: GAL treatment elevated AGE levels, ROS formation and protein and lipid oxidation products in serum and examined tissues. CAR treatment was observed to decrease significantly glyco-oxidative stress in serum, liver and brain tissues of GAL-treated rats. Conclusion: Our results indicate that CAR may be useful for decreasing oxidative stress and glycation products in GAL-induced aging model in rats. © 2018 Bentham Science Publishers. Istanbul Üniversitesi: 42685 The present work was supported by Research Fund of Istanbul University (Project No: 42685).

Published
2018

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