1. Illuminating pathogen–host intimacy through optogenetics.
- Author
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Arroyo-Olarte, Ruben Dario, Thurow, Laura, Kozjak-Pavlovic, Vera, and Gupta, Nishith
- Subjects
- *
OPTOGENETICS , *NEUROSCIENCES , *BRAIN , *INTRACELLULAR pathogens , *PATHOGENIC microorganisms - Abstract
The birth and subsequent evolution of optogenetics has resulted in an unprecedented advancement in our understanding of the brain. Its outstanding success does usher wider applications; however, the tool remains still largely relegated to neuroscience. Here, we introduce selected aspects of optogenetics with potential applications in infection biology that will not only answer long-standing questions about intracellular pathogens (parasites, bacteria, viruses) but also broaden the dimension of current research in entwined models. In this essay, we illustrate how a judicious integration of optogenetics with routine methods can illuminate the host–pathogen interactions in a way that has not been feasible otherwise. [ABSTRACT FROM AUTHOR]
- Published
- 2018
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