1. A single-centre retrospective review of unilateral and bilateral Dysport® injections in adductor spasmodic dysphonia.
- Author
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Elmiyeh, Behrad, Prasad, Vyas M. N., Upile, Tahwinder, Saunders, Nick, Youl, Bryan D., Epstein, Ruth, and Rubin, John S.
- Subjects
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SPASMODIC dysphonia , *VOICE disorders , *NEUROTOXIC agents , *CLOSTRIDIUM botulinum , *BACTERIAL toxins - Abstract
We reviewed the results and side-effect profile of the Dysport® preparation of botulinum toxin A (BTA) in the management of the adductor spasmodic dysphonia. We performed 272 injection episodes in 68 patients, 42 (62%) female, 26 (38%) male. A total of 116 of these injections were unilateral, and 156 were bilateral; 94% of the injections were considered to have been successful with a voice score of 2 or higher. The mean duration of effect (injection intervals) was 128.8 days in the unilateral cohort and 118.7 days in the bilateral ( P > 0.05). We injected a relatively lower dose of BTA for unilateral injection episodes in our institution compared to those reported by others to produce comparable results and side-effect profiles. [ABSTRACT FROM AUTHOR]
- Published
- 2010
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