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Feature selection plays an important role in data preprocessing. The aim of feature selection is to recognize and remove redundant or irrelevant features. The key issue is to use as few features as possible to achieve the lowest classification error rate. This paper formulates feature selection as a multi-objective problem. In order to address feature selection problem, this paper uses the multi-objective bacterial foraging optimization algorithm to select the feature subsets and k-nearest neighbor algorithm as the evaluation algorithm. The wheel roulette mechanism is further introduced to remove duplicated features. Four information exchange mechanisms are integrated into the bacteria-inspired algorithm to avoid the individuals getting trapped into the local optima so as to achieve better results in solving high-dimensional feature selection problem. On six small datasets and ten high-dimensional datasets, comparative experiments with different conventional wrapper methods and several evolutionary algorithms demonstrate the superiority of the proposed bacteria-inspired based feature selection method. [ABSTRACT FROM AUTHOR]