1. Diagnostic and therapeutic yield of imaging studies in Polymicrobial and Monomicrobial Gram-negative bloodstream infections - a retrospective cohort study.
- Author
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Massalha M, Mahamid L, Ishay L, Freimann S, Cohen R, and Reisfeld S
- Subjects
- Humans, Retrospective Studies, Male, Female, Middle Aged, Aged, Adult, Drainage methods, Aged, 80 and over, Gram-Negative Bacteria isolation & purification, Gram-Negative Bacteria drug effects, Anti-Bacterial Agents therapeutic use, Gram-Negative Bacterial Infections diagnosis, Gram-Negative Bacterial Infections mortality, Gram-Negative Bacterial Infections microbiology, Gram-Negative Bacterial Infections drug therapy, Bacteremia microbiology, Bacteremia drug therapy, Bacteremia diagnosis, Bacteremia mortality, Coinfection microbiology, Coinfection diagnosis
- Abstract
Purpose: Appropriate antimicrobial therapy and surgical drainage, improve survival in patients with Gram negative bloodstream infections (BSI). Data about the yield of imaging studies in polymicrobial BSI is sparse. The aim of the study was to assess the need for imaging studies and surgical drainage among patients with polymicrobial compared to monomicrobial BSI., Results: In a retrospective cohort study of adult patients with Gram negative BSI, 135 patients with monomicrobial BSI were compared to 82 with polymicrobial BSI. Imaging studies were performed in 56.3 % of patients with monomicrobial BSI and in 50 % of polymicrobial BSI (p=0.4), surgical drainage was performed in 20.1 % of patients with monomicrobial BSI and 27.2 % of polymicrobial BSI (p=0.25). Surgical drainage was performed in 26.2 % of patients who survived vs. 11.8 % of patients who died (p=0.035)., Conclusions: There is no difference in the diagnostic approach to monomicrobial and polymicrobial Gram-negative BSI. Surgical drainage is associated with decreased mortality., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024. Published by Elsevier Inc.)
- Published
- 2024
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