1. Transmission of type 1 diabetes by bone marrow transplantation: A case report.
- Author
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Mellouli, Fethi, Ksouri, Habib, Torjmen, Lamia, Abdelkefi, Abderrahman, Ladeb, Saloua, Othman, Tarek Ben, Hassen, Assia Ben, and Béjaoui, Mohamed
- Subjects
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ANEMIA , *BONE marrow transplantation , *ENDOCRINE diseases , *HEMATOPOIETIC system , *BLOOD diseases - Abstract
T1D after BMT constitutes a human model of autoimmune disease transmission. This case report refers to T1D onset after allogeneic HLA-matched BMT in a six-yr-old recipient affected by aplastic anemia. The donor was his sister who had T1D. The recipient had a complication free course apart from grade 1 acute GVHD, which was resolved spontaneously. With the predictive value and significance of T1D-associated autoantibodies, we tried to consolidate the T1D transfer possibility based on our patient characteristics and a literature review. [ABSTRACT FROM AUTHOR]
- Published
- 2009
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