1. Analysis of National Surveillance of Respiratory Pathogen for Children and Adolescents’ Community Acquired Pneumonia
- Author
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Eun Sil Lee, Hyo-Bin Kim, Ju-Hee Seo, JeeYoung Lee, Yang Park, Bong Seok Choi, Dong Hyuk Kim, Su Jin Lee, En Seok Yang, Hae Young Yew, Jung Yeon Shim, Hyung Min Cho, Jin Taek Kim, En Lee, Hyun Jong Yang, Ja Koung Kim, Mi Yong Shin, Eun Kyoung Kang, Hae Lee Chung, Eun-Ae Yang, Yoon Young Jang, Bong Seong Kim, Eui Jeong Roh, Seung Taek You, Man Yong Han, Mi-Hee Lee, Yoon ha Whang, Myoung Soon Sung, Sangun Jeong, Young Min Ahn, Hyoung young Kim, Eun hee Chung, Jin A Jung, Kyu Jam Whang, and Min-Ji Kim
- Subjects
medicine.medical_specialty ,business.industry ,Respiratory infection ,medicine.disease ,Pneumonia ,Antibiotic resistance ,Community-acquired pneumonia ,Atypical pneumonia ,Internal medicine ,Epidemiology ,medicine ,Sputum ,Respiratory virus ,medicine.symptom ,business - Abstract
Background Respiratory infection in children is a major disease that ranks high in outpatient and inpatient cases. In particular, the causes of community acquired pneumonia (CAP) vary depending on the individual susceptibility, epidemiological characteristics of the community, and season, and it is difficult to obtain samples for microbiological diagnosis. This study analysis that laboratory surveillance network of pathogen for pediatric CAP by linking the national community-based hospital and clinics and the Centers for Disease Control and Prevention (KCDC) to identify the distribution trend and prevalence of causative pathogens and to prevent antibiotic resistance of bacterial pathogens. Method The monitoring network was composed of the 28 secondary and tertiary medical institutions based on the national community, and the 24-month prospective study operated a community monitoring network for CAP in children. Results A total of 1023 cases were registered for nasopharyngeal aspirate or sputum in patients with CAP, and 711 cases (69.5%) were isolated by culture, S. aureus 131 cases (12.8%), S. pneumonia 92 cases (9%), H. influenzae 20 cases (2%). PCR of atypical pneumonia revealed 422 cases of M. pneumoniae (41.3%), 5 cases of C. pneumonia (0.5%), and 5 case (0.5%) of B. pertussis. Respiratory virus multiplex PCR test showed positive rates in 65.7%, human rhinovirus 312 (30.5%), RSV(A+B) 212 (20.7%), Adenovirus 123 (12%), Influenza (A+B) 53 (7.8%), CoV (OC43+NL63+229E) 69 (6.7%), HMPV 81 (7.9%), HBoV 51 (5%), PIV (1+2+3+4) 65 (6.4%) and HEV 30 (2.9%) Conclusion It will identify the pathogens that cause respiratory infections, and analyze the current status of antibiotic resistance to provide scientific evidence for management policies of domestic respiratory infection. Also, in preparation for the new epidemic, including COVID19, monitoring of respiratory infections in children and adolescents, especially community pneumonia, has become more important, and research should be continuously conducted in the future. The location and extent of involvement in the medulla were the most important factors associated with the severity of dysphagia after LMI.
- Published
- 2021