1. Left atrial ejection force predicts the outcome after catheter ablation for paroxysmal atrial fibrillation.
- Author
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Kishima H, Mine T, Takahashi S, Ashida K, Ishihara M, and Masuyama T
- Subjects
- Action Potentials, Aged, Atrial Fibrillation diagnostic imaging, Atrial Fibrillation physiopathology, Echocardiography, Doppler, Echocardiography, Transesophageal, Female, Heart Atria diagnostic imaging, Heart Atria physiopathology, Heart Rate, Humans, Male, Middle Aged, Recurrence, Retrospective Studies, Risk Assessment, Risk Factors, Systole, Time Factors, Treatment Outcome, Atrial Fibrillation surgery, Atrial Function, Left, Catheter Ablation adverse effects, Heart Atria surgery
- Abstract
Introduction: Left atrium (LA) systolic dysfunction is observed in the early stages of atrial fibrillation (AF) prior to LA anatomical change. We investigated whether LA systolic dysfunction predicts recurrent AF after catheter ablation (CA) in patients with paroxysmal AF., Methods and Results: We studied 106 patients who underwent CA for paroxysmal AF. LA systolic function was assessed with the LA emptying volume = Maximum LA volume (LAV
max ) - Minimum LA volume (LAVmin ), LA emptying fraction = [(LAVmax - LAVmin )/LAVmax ] × 100, and LA ejection force calculated with Manning's method [LA ejection force = (0.5 × ρ × mitral valve area × A2 )], where ρ is the blood density and A is the late-diastolic mitral inflow velocity. Recurrent AF was detected in 35/106 (33%) during 14.6 ± 9.1 months. Univariate analysis revealed reduced LA ejection force, decreased LA emptying fraction, larger LA diameter, and elevated brain natriuretic peptide as significant variables. On multivariate analysis, reduced LA ejection force and larger LA diameter were independently associated with recurrent AF. Moreover, patients with reduced LA ejection force and larger LA diameter had a higher risk of recurrent AF than preserved LA ejection force (log-rank P = 0.0004)., Conclusions: Reduced LA ejection force and larger LA diameter were associated with poor outcome after CA for paroxysmal AF, and could be a new index to predict recurrent AF., (© 2017 Wiley Periodicals, Inc.)- Published
- 2018
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