1. Translational development of ABCB5
- Author
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Andreas, Kerstan, Kathrin, Dieter, Elke, Niebergall-Roth, Sabrina, Klingele, Michael, Jünger, Christoph, Hasslacher, Georg, Daeschlein, Lutz, Stemler, Ulrich, Meyer-Pannwitt, Kristin, Schubert, Gerhard, Klausmann, Titus, Raab, Matthias, Goebeler, Korinna, Kraft, Jasmina, Esterlechner, Hannes M, Schröder, Samar, Sadeghi, Seda, Ballikaya, Martin, Gasser, Ana M, Waaga-Gasser, George F, Murphy, Dennis P, Orgill, Natasha Y, Frank, Christoph, Ganss, Karin, Scharffetter-Kochanek, Markus H, Frank, and Mark A, Kluth
- Subjects
Vascular Endothelial Growth Factor A ,Wound Healing ,ATP Binding Cassette Transporter, Subfamily B ,Neovascularization, Pathologic ,Neovascularization, Physiologic ,Mesenchymal Stem Cells ,Dermis ,Mesenchymal Stem Cell Transplantation ,Diabetic Foot ,Mice ,Ischemia ,Diabetes Mellitus ,Animals ,Humans ,RNA, Messenger - Abstract
While rapid healing of diabetic foot ulcers (DFUs) is highly desirable to avoid infections, amputations and life-threatening complications, DFUs often respond poorly to standard treatment. GMP-manufactured skin-derived ABCB5The angiogenic potential of ABCB5Hypoxic incubation of ABCB5The present observations identify GMP-manufactured ABCB5ClinicalTrials.gov, NCT03267784, Registered 30 August 2017, https://clinicaltrials.gov/ct2/show/NCT03267784.
- Published
- 2022