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Objective: Sleep is a vital component of human life that serves many critical roles in physical and mental health, and well-being. There were few studies on children, diagnosed with allergic diseases, especially preschool children. The aim of our study mas to evaluate sleep disorders in children with allergic diseases. Material and Methods: This retrospective study was conducted in Dr. Burhan Nalbantoğlu Hospital Child Immunology and Allergy outpatient clinic between January 1 and March 20, 2024, patients included who were diagnosed with allergic rhinitis, asthma and/or atopic dermatitis.The 'Sleep Disturbance Scale for children (SDSC) was applied to the parents by the researcher during the outpatient clinic visit. Results: In this study, 145 patients were involved. Five (3.4%) patients had clinically significant SDSC score. There was a statistically significant difference in the Children's Sleep Disturbance Scale mean score between having and not having symptoms of allergic diseases. Patients diagnosed wheezy child tended to have higher mean score of SHY. Among patients having symptoms of allergic diseases, there was statistically significant difference in the SDSC mean score between having nose congestion, cough, and activity limitation and not having these symptoms. Patients using oral antihistaminic treatment tended to have higher total mean scores of SDSC. Conclusion: In this study, out of 145 patients, 5 (3.4%) patients had clinically significant SDSC score. Patients having symptom of allergic diseases tended to have higher total mean score of childrens' sleep disturbance scale. Patients diagnosed wheezy child tended to have higher mean score of SHY. Patients having nose congestion, cough, and activity limitation tended to have higher total mean score of SDSC. [ABSTRACT FROM AUTHOR]

Objective: To determine the prevalence and associated risk factors of asthma and allergic diseases in school children and adolescents in Adıyaman, Turkey. Material and Methods: The International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire was completed online by parents of 280 children aged 6-7 years and 163 adolescents aged 13-14 years living in Adıyaman. Additional questions were added to the online survey to determine the prevalence of food and drug allergies. Results: The prevalence of allergic diseases in the 6-7 and 13-14 age groups were as follows: 23.2% and 18.4% for asthma, 21.4% and 18.4% for allergic rhinitis, 11.4% and 11% for eczema, 10.4% and 8.6% for food allergy, and 8.6% and 3.7% for drug allergy. In the 6-7-year age group, male sex was associated with asthma and allergic rhinitis; cesarean delivery with drug allergy; and fewer siblings with atopic eczema and drug allergy. In the 13-14-year age group, having pets and more siblings were associated with eczema and food allergy, respectively. Conclusion: This is the first study that demonstrated the prevalence of allergic diseases in Adıyaman province and showed that the overall prevalence of allergic diseases is high in the region. [ABSTRACT FROM AUTHOR]

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Objective: Atopic march is a model that explains the progression of allergic diseases from atopic dermatitis (AD) to allergic asthma and rhinitis. In our study, while evaluating the presence of allergen sensitivity and allergic diseases in patients who were diagnosed with AD and followed up until the age of at least 5 years, we wanted to investigate how much the definition of classical atopic gait responded to expectations. Material and Methods: We retrospectively reviewed the file records of patients diagnosed with atopic dermatitis, whose ages were 2 years and under at the time of application and followed up regularly until at least 5 years of age. We recorded the clinical and laboratory findings. We noted the allergic disease status and allergen sensitivity of the patients when they were 5 years old. Results: Forty-one patients with a diagnosis of AD who met the criteria were identified. During the application, we found food sensitivity in 28 (68.3%) patients. When 41 patients reached the age of 5, 13 (31.7%) were diagnosed with asthma and 12 (29.2%) were diagnosed with allergic rhinitis. Conclusion: We found the frequency of asthma and allergic rhinitis higher in patients with AD than in the normal population. However, we could not show a relationship between food sensitivity and the development of asthma and/or allergic rhinitis. Effective skin care in AD can be protective for developing of allergic diseases. In order for clinicians to understand the heterogeneity of atopic disease models in children and to eliminate this variability, infants with AD should be followed up in later life. [ABSTRACT FROM AUTHOR]

Objective: Skin prick test (SPT) is mainly used for diagnosis and follow-up of diseases like atopic dermatitis (AD), chronic urticaria (CU), allergic asthma (AA) and allegic rhinitis (AR). The aim of current study is to explore the results of SPT retrospectively which were performed in Dermatology Outpatient Allergy Unit (DOAU) for identifying indications and positivity. Methods: Results of SPT which were performed on 2014-2016 were investigated based on archives of DOAU. Results of SPT were analyzed from the SPT Forms which were prepared for each patient. Results: SPT were performed on 1916 individuals who admitted to DOAU during 2015-2016. AA was determined in 941, AR in 133 and dermatological diseases were 842 patients. SPT positive results, for at least one or more allergen agents, of patients with AA, AR and dermatological diseases were 92.1%, 71.4% and 50% respectively. Dermatological diseases included; except CU in 69 patients and AD in 55 patients. In the remaining 718 patients were diagnosed with dermatitis, idiopathic generalised pruritus (IGP) and other dermatological disorders. SPT positivity rates in CU was 55.1%, 52.7% in AD and 48.6% in several dermatological diseases. Conclusions: As a result, the rate of SPT positivity in patients with AA and AR were higher than both CU, AD and several dermatological diseases. The reason of this may be related with lesser role of type 1 hypersensivity reaction in etiopathogenesis of CU and AD, and/or improper SPT indications who were directed with diagnosis of several dermatological diseases. [ABSTRACT FROM AUTHOR]

Objective: To detect the positivity ratio of prick test and to investigate the distribution of allergens according to the age, gender, pre-diagnosis and seasons in Giresun. Methods: In this study, 330 patients undergone skin prick test in 12 month- period were included. Reviewing retrospectively, ages, genders, pre-diagnosis, seasons and results of the prick tests were noted. Ratio of test positivity and multiple allergen positivity were compared between children and adults. Results: Of 330 patients, 92 (27.9 %) had allergic rhinitis, 73 (22.1 %) had urticaria, 59 (17.9 %) had chronic cough, 50 (15.1%) had chronic pruritus, 25 (7.6 %) had atopic dermatitis, 25 (7.6 %) had contact dermatitis and 6 (1.8 %) had angioneurotic edema. Highest test positivity was evident in angioneurotic edema (83.3 %) and allergic rhinitis (65.2 %) patients. Of the patients, 106 (66.7 %) had mite sensitivity (house dust and warehouse), 44 (27.7 %) had meadow and grass pollen sensitivity, and 43 (27%) had tree pollen sensitivity. The most frequent allergen type was house dust mites in allergic rhinitis patients [D. Pteronyssnus (55%) and D. Farinae (50%)]. In children, the highest ratio of test positivity was in allergic rhinitis (72.7%) and atopic dermatitis patients (50%). No difference was evident between the ratio of test positivity and multiple allergen positivity of children and adults (X² = 0.417, p=0.519 and X² = 0.383, p=0.536; respectively). Conclusions: The most common pre-diagnosis for prick test was allergic rhinitis. Highest test positivity was in angioneurotic edema and allergic rhinitis patients. The most common allergen type was house dust mite. [ABSTRACT FROM AUTHOR]

Objective: Atopic dermatitis (AD) is the most frequent inflammatory skin disease in childhood. Atopic dermatitis, as the first manifestation of atopic march may continue as asthma and allergic rhinitis. The aim of this study was to evaluate the early prognosis of AD in children. Material and Methods: Children who were diagnosed with AD before three years old between March 2009 and January 2012, and were followed for at least 2 years in the Pediatric Allergy Department of our tertiary hospital were enrolled in this study. Persistence of AD symptoms and development of asthma and/or allergic rhinitis were explored. Results: One hundred and four patients (59 male, 45 female) were included in the study. Atopic dermatitis persisted in 14 (13.5%) patients. Fourteen patients (13.5%) developed allergic rhinitis and 16 (15.4%) patients developed asthma. Food allergy was found to be a risk factor for persistence of AD lesions (OR (5.1) CI (1.4-18.3) (p=0.011).The presence of parental asthma (OR (6.2) (1.4-27.6) p=0,015) and persistence of AD lesions (OR (7.2) (1.7-34.9) p=0.007) were found to be risk factors for the development of asthma and/or allergic rhinitis. Conclusion: Persistence of atopic dermatitis and development of asthma and/or allergic rhinitis were significantly lower in our study group than in the literature. Long-term follow-up of patients with AD is required. [ABSTRACT FROM AUTHOR]

Aim: An inverse association between markers of exposure to orofecal pathogens such as hepatitis A and allergic disease has been reported. However, the findings of studies have not been consistent. In this study we compared to the frequency of allergic symptoms and asthma in children with hepatitis A seropositive and seronegative. Materials and Methods: This study was performed in 499 children admitted to our Hospital and in whom we determined specific IgG in serum to hepatitis A virus (HAV). The demographical findings of the children were recorded. They were examined by using ISAAC (International Study of Asthma and Allergies in Childhood) questionnaire. Results: The mean age of 449 children was 9.28±2.24 (1-16y) years. 47.7% of the children were female and 52.3% were male. Anti-HAV IgG serology was found positive in 261 children and negative in 238 children. The frequency of physician-diagnosed asthma that kept them awake at night ≤1 per week on average by this itchy rash were found to be high in children with hepatitis A seronegative. Attacks of wheezing in the last 12 months, speech-limiting wheeze and rhinoconjunctivitis in the last 12 months were high in children with hepatitis A seropositive. Conclusion: The frequency of physician-diagnosed asthma is higher in children with hepatitis A seronegative. Significant differences between the two groups in terms of allergic symptoms were observed. [ABSTRACT FROM AUTHOR]

Objective: Aim of the study was assessment of allergen susceptibility at patient with allergic symptoms at Hatay/Dortyol using the skin prick test. Material and Method: Skin prick test results of patients with asthma, allergic rhinitis, chronic urticaria, and atopic dermatitis at Dortyol State Hospital Pulmonary Disease and Dermatology outpatient clinics between January 2008 and December 2008. Results: 17,961 different patients were treated at outpatient clinics. 2950 patients (1467 female, 483 male) were included in the study and mean age was 29.7±16.8 years. There were 228 patients with allergic rhinitis, 1139 patients with asthma, 256 patients with chronic urticaria, and 327 patients with atopic dermatitis. Presence of atopy in females (74.6%) was more seen than in males (65.2%). According to the months, atopy was seen more frequently in April (91.5%), May (81.9%), and March (79.2%). Atopy in allergic rhinitis, asthma, atopic dermatitis, and chronic urticaria were 82.9%, 76.6%, 61.8%, and 57%, respectively. More frequently seen allergens in all patients were house mites (48.5%), grass mix (39.5%), and mould mix (37.6%). Conclusion: Atopy in Hatay/Dortyol is frequently seen. [ABSTRACT FROM AUTHOR]