1. Three new polyketides from marine-derived fungus Aspergillus glaucus HB1-19.
- Author
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Sun SW, Ji CZ, Gu QQ, Li DH, and Zhu TJ
- Subjects
- Benzyl Compounds chemistry, Benzyl Compounds pharmacology, Biphenyl Compounds pharmacology, Free Radical Scavengers chemistry, Free Radical Scavengers pharmacology, Marine Biology, Molecular Structure, Naphthoquinones chemistry, Naphthoquinones pharmacology, Nuclear Magnetic Resonance, Biomolecular, Picrates pharmacology, Polyketides chemistry, Polyketides pharmacology, Aspergillus chemistry, Benzyl Compounds isolation & purification, Free Radical Scavengers isolation & purification, Naphthoquinones isolation & purification, Polyketides isolation & purification
- Abstract
Two new benzyl derivatives, aspergentisyl A (1) and aspergentisyl B (2), as well as one new naphthoquinone derivative, aspergiodiquinone (3), together with seven known prenylated benzaldehyde derivatives (4-10) were isolated from the marine-derived fungus Aspergillus glaucus HB1-19. The structures of these compounds were characterized based on 1D and 2D NMR spectra analyses and comparison with those reported in the literature. In addition, each isolate was tested for its 1,1-diphenyl-2-picrylhydrazyl radical-scavenging property and all these compounds except compound 3 exhibited strong radical-scavenging activity.
- Published
- 2013
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