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A study conducted at Chongqing University in China focused on the use of MBene nanosheets for detecting circulating tumor DNA (ctDNA) in blood samples. The research highlighted the exceptional DNA adsorbability of MBene nanosheets and their ability to discriminate between single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA). The study also developed a sensitive fluorescence biosensor for ctDNA detection and a paper-based microfluidic chip for point-of-care testing, demonstrating promising results for cancer diagnosis and treatment monitoring. The research findings have been peer-reviewed and offer potential applications in bioimaging and nucleic acid sequencing. [Extracted from the article]

Researchers at Nanjing University of Science and Technology in Jiangsu, China, have developed a fluorescent biosensor using bacteria-instructed atom transfer radical polymerization (ATRP) for highly sensitive detection of Escherichia coli and Staphylococcus aureus, common foodborne pathogens. This innovative method involves attaching initiators of ATRP to magnetic beads and utilizing the bacteria's redox pathway to grow fluorescent polymers, enhancing sensitivity. The biosensor offers a simple, efficient, and stable solution for direct detection of these bacteria, showing promise for application in complex food samples. The study was published in Analytica Chimica Acta and has been peer-reviewed. [Extracted from the article]

A recent study conducted at Nanjing Agricultural University in China has developed a novel biosensor for the simultaneous detection of Salmonella typhimurium and Staphylococcus aureus in chicken samples. The biosensor utilizes upconversion fluorescence technology and a self-designed cuvette filled with modified nanoparticles. The detection process is rapid, requiring only 40 minutes, and has a low limit of detection for both bacteria. This research shows promise for the rapid analysis and detection of foodborne pathogenic bacteria. [Extracted from the article]

A study conducted at Jiangxi Normal University in Nanchang, People's Republic of China, has developed a stable DNA signal amplification sensor using rolling circle amplification (RCA) technology. This biosensor can detect DNA fragments with genetic information, making it a universal tool for DNA detection. The study focused on using the biosensor to detect the homologous DNA of human immunodeficiency virus (HIV) and let-7a. By regulating the distance between the quenching group and the fluorescent group, the biosensor was able to recover the fluorescence signal. This research has been peer-reviewed and published in Microchimica Acta. [Extracted from the article]

A study conducted at Guangxi University in Nanning, China has developed a binary split fluorescent DNA aptasensor (bsFDA) for the analysis of Hepatitis B viral DNA. The bsFDA is able to detect specific DNA sequences related to Hepatitis B, providing a fast and reliable fluorescence readout without the need for enzymes or chemical labeling. The aptasensor has been successfully applied to analyze Hepatitis B DNA in biological samples such as human serum and cell lysate. This research holds potential for the development of functionalized aptasensors and the analysis of viral genomes in biological research. [Extracted from the article]

Researchers from National Sun Yat-Sen University in Kaohsiung City, Taiwan have developed a highly sensitive and selective method for detecting the antibiotic ciprofloxacin using silver dimolybdate nanosheets. The method utilizes the properties of Aggregation-Induced Emission (AIE) to produce a bright fluorescence response with a low detection limit. The researchers believe that this approach has broad practical implications for human health monitoring and pharmaceutical quality control. The study highlights the potential of using non-fluorescent 2D nanosheets as effective fluorescent biosensors. [Extracted from the article]

A recent study conducted at Dezhou University in China has developed a low-background fluorescent biosensor for the sensitive detection of kanamycin in milk samples. The biosensor utilizes graphene oxide and aptamer biorecognition to achieve label-free and low-background detection. The biosensor demonstrated a linear calibration curve in the range of 1-400 nM with a detection limit of 0.60 nM for kanamycin. The researchers concluded that this biosensor has the potential to be a powerful tool for monitoring food safety. [Extracted from the article]

Researchers from the University of Jinan in Guangzhou, China have developed a novel graphene oxide-based fluorescence biosensor for screening high affinity monoclonal antibody (mAb) producing hybridomas. The biosensor combines biosensing and flow cytometry to create a rapid and high-throughput method for screening mAb producing clones. The sensor utilizes a FITC-labeled peptide that is adsorbed on the surface of graphene oxide, resulting in fluorescence quenching. The specific mAb competitively binds to the peptide, causing fluorescence recovery. The sensor is simple, inexpensive, highly specific, and can be used for cell sort assay and screening other mAb hybridomas libraries. [Extracted from the article]

A study conducted by Nanchang University in China has developed a novel fluorescence signal amplification biosensor for the detection of Escherichia coli O157:H7 (E. coli O157:H7) in food. The biosensor utilizes magnetic separation and breakable organosilica nanocapsules to capture and detect the bacteria. The method has a limit of detection of 25 CFU/mL and can be completed in approximately 120 minutes. The researchers believe that this biosensor has the potential to be adapted for the detection of other pathogens in food by modifying specific antibodies. [Extracted from the article]

A recent study conducted at Xiamen University in China has developed a purification-free fluorescence biosensor for the ultrasensitive detection of circulating tumor DNA (ctDNA). The biosensor combines nicking enzyme mediated amplification (NEMA) and catalytic hairpin assembly (CHA) reactions to achieve an impressive signal amplification of nearly 107-fold, allowing for the detection of ctDNA with ultra-sensitivity. The biosensor also showed favorable sensitivity in the presence of human serum, eliminating the need for an intermediate purification step and enhancing convenience. This research has the potential to serve as an effective diagnostic tool for the early detection of cancer. [Extracted from the article]

A new study conducted by researchers at the Chinese Academy of Agricultural Sciences in Changchun, China, has developed a fluorescent biosensor for the detection of the pathogenic bacteria Escherichia coli O157:H7. The biosensor utilizes a catalytic hairpin assembly and lambda-Exonuclease cleavage reaction, allowing for rapid and precise detection. The researchers successfully identified Escherichia coli O157:H7 within a wide range of concentrations, with a detection limit of 10 CFU/mL. This innovative design philosophy could also be applied to identify other target pathogenic bacteria. The research has been peer-reviewed and published in Sensors and Actuators B: Chemical. [Extracted from the article]

A recent study conducted at Changchun University of Science and Technology in China has developed a novel biosensor for the specific detection of foodborne pathogens. The biosensor utilizes a CRISPR/Cas12a system and split crRNA to detect pathogenic bacteria. The biosensor demonstrated excellent performance in detecting Staphylococcus aureus in milk samples, with a low detection limit and wide linear range. This research provides a promising approach for improving food safety and preventing foodborne diseases. [Extracted from the article]

A recent report from the National Key Laboratory of Biochemical Engineering in Beijing, China, discusses the development of an ultra-sensitive fluorescent biosensor for the detection of multiple bacteria. The biosensor utilizes zeolitic imidazolate frameworks (ZIF-8) to encapsulate fluorescence signal molecules, and magnetic nanoparticles (MNPs) to capture target bacteria. The biosensor was able to detect Escherichia coli O157:H7, Salmonella paratyphi A, and Salmonella paratyphi B at concentrations as low as 10 CFU/mL within 1.5 hours. The research also demonstrated the applicability of the biosensor in detecting bacteria in real samples, with a mean recovery rate of 99.18% in spiked milk samples. [Extracted from the article]

A recent study conducted at Xi'an University of Science and Technology in China has developed a fluorescence biosensor for the detection of mercury ions (Hg2+). The biosensor utilizes carbon quantum dots made from pomegranate peel (P-CQDs) and a G-quadruplex binding with hemin to detect the presence of Hg2+. The biosensor demonstrated strong sensitivity, high selectivity, and low cost for detecting Hg2+ in environmental water samples. This research provides valuable insights into the development of biosensors for the detection of harmful substances in daily life. [Extracted from the article]

A recent report from Chongqing University in China discusses the development of an ultrasensitive and label-free fluorescent biosensor for the detection of circulating tumor DNA (ctDNA), which is a potential cancer biomarker. The biosensor utilizes a combination of CRISPR/Cas12a cleavage and exponential amplification to produce G-rich sequences that can form a dimeric G-quadruplex and enhance fluorescence. The biosensor demonstrated excellent sensitivity at the aM level and showed reliable accuracy in complex serum environments and tumor cell lysates. This research offers practical insights for molecular diagnostics and clinical applications, simplifying the construction of fluorescent biosensors and avoiding the need for complicated labeling processes. [Extracted from the article]

A recent study conducted at Xi'an University of Science and Technology in China has developed a fluorescence biosensor for the detection of mercury ions (Hg2+). The biosensor utilizes carbon quantum dots made from pomegranate peel (P-CQDs) and a G-quadruplex binding with hemin to detect the presence of Hg2+. The biosensor demonstrated strong sensitivity, high selectivity, and low cost for detecting Hg2+ in environmental water samples. This research provides valuable insights into the development of biosensors for the detection of harmful substances in daily life. [Extracted from the article]

A recent study conducted at Northwest University in Xi'an, China, has developed a fluorescent biosensor for the detection of lead ions using carbon quantum dots derived from grapefruit peel. Lead ions are a type of heavy metal that can contaminate the environment and pose a risk to human health. The biosensor utilizes a lead ion-DNAzyme cleavage mechanism and a hemin/carbon quantum dot complex to detect lead ions. The biosensor demonstrated excellent selectivity and sensitivity, with a limit of detection of 5 nM for lead ions. This research provides a potential method for testing water samples for lead contamination. [Extracted from the article]

A recent study conducted at Xi'an University of Science and Technology in China has developed a novel fluorescent biosensor for detecting lead (Pb2+). The biosensor utilizes magnetic beads modified with a specific DNAzyme and carbon dots synthesized from watermelon rind as recognition probes. The presence of Pb2+ triggers the biosensor, generating a G-quadruplex that restores the fluorescence of the carbon dots. The research concluded that the biosensor's fluorescence change is dependent on Pb2+ concentration. This study was supported by the National Natural Science Foundation of China. [Extracted from the article]

A recent report from investigators at Qingdao University of Science and Technology in China discusses the development of fluorescent biosensors for detecting and imaging caspase activation in biomedical applications. Caspases are enzymes that play a critical role in maintaining cellular homeostasis and are involved in various cell death pathways. The researchers emphasize the importance of accurately measuring caspase activity to understand the molecular mechanisms underlying different diseases. The report provides a systematic summary of caspase classification and functions in different diseases, as well as the latest developments in biosensors for detecting caspase activity. The research concludes by proposing future research directions and challenges in this field. [Extracted from the article]

Researchers at Huazhong Agricultural University in Hubei, China, have developed a machine vision-assisted fluorescence biosensor for the detection of viable Salmonella in food without the need for complex DNA extraction and amplification procedures. The biosensor combines machine vision and learning with a phage and Clostridium butyricum Argonaute (CbAgo) to detect viable Salmonella typhimurium. The biosensor demonstrated high sensitivity and selectivity, with a limit of detection at 40.5 CFU/mL and a linear range of 50-10 CFU/mL. This method reduces the use of chemical reagents and experimental consumables compared to other Salmonella detection methods. [Extracted from the article]

A report from Baghdad, Iraq discusses the development of dual-mode colorimetric and fluorescence biosensors for the detection of foodborne bacteria. The integration of two detection signals, fluorescent and colorimetric, has shown potential in improving diagnostic performance and enhancing food safety. The research examines various sensing methods and their application in detecting foodborne bacteria, as well as the challenges and future prospects in this field. The study has been peer-reviewed and provides valuable insights into the advancement of biosensor technology for food safety. [Extracted from the article]

A new report discusses research findings on biosensors from Jiangsu University in Zhenjiang, China. The researchers developed a fluorescent biosensor that can simultaneously detect aflatoxin B1 (AFB1) and aflD genes, which can help monitor and reduce safety issues and economic losses caused by aflatoxin production. The biosensor utilizes quantum dots and a black hole quenching agent to detect the presence of AFB1 and aflD genes. The method has a wide linear range and has been validated in real rice flour and corn flour samples. The researchers believe that this biosensor can significantly improve food safety and quality control. [Extracted from the article]

A recent report from investigators at Zhengzhou University in Henan, China discusses advances in enzyme-free nucleic acid amplification-based fluorescent biosensors for real-time imaging of DNA repair enzymes in living cells. DNA repair enzymes play a crucial role in maintaining the stability and integrity of cellular genomic DNA. Abnormal DNA repair enzyme activity can lead to cell growth stagnation, cell death, and the development of diseases such as cancer. The researchers review the mechanisms, applications, and performance of different enzyme-free nucleic acid amplification approaches for DNA repair enzyme imaging, as well as potential challenges and future perspectives in the field. This research was supported by the National Natural Science Foundation of China. [Extracted from the article]

Researchers from Hebei University in Baoding, China have developed a highly sensitive and specific fluorescence biosensor for detecting 5-hydroxymethylcytosine (5hmC), which is closely correlated with cancer occurrence and development. The biosensor utilizes M.HhaI methyltransferase catalysis and an improved isothermal exponential amplification reaction (imEXPAR) to detect 5hmC. The assay has a linear range of 100 aM-1 nM and a limit of detection of 37.4 aM, demonstrating high sensitivity. The biosensor also showed good stability and selectivity in distinguishing 5hmC from 5mC, and it performed well in human serum samples and genomic analysis of mice tissues. This research has been peer-reviewed and published in Sensors and Actuators B: Chemical. [Extracted from the article]

A research study conducted at the University of Jinan in Guangzhou, China has developed a new dual aptamer recognition-based fluorescent biosensor for ultrasensitive cancer-derived extracellular vesicles (EVs) assays. The biosensor utilizes functionalized metal organic frameworks (MOFs) and rolling circle amplification (RCA) to achieve high sensitivity and specificity in detecting EVs. The method has been successfully used for the diagnosis of leukemia and shows potential for early clinical disease diagnosis. The research has been peer-reviewed and published in Sensors and Actuators B: Chemical. [Extracted from the article]

Keywords: Fujian; People's Republic of China; Asia; Bacterial Infections and Mycoses; Biosensors; Biotechnology; Fluorescent Biosensors; Health and Medicine; Nanotechnology EN Fujian People's Republic of China Asia Bacterial Infections and Mycoses Biosensors Biotechnology Fluorescent Biosensors Health and Medicine Nanotechnology 4439 4439 1 10/16/23 20231020 NES 231020 2023 OCT 20 (NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on Biosensors - Fluorescent Biosensors have been published. Keywords for this news article include: Fujian, People's Republic of China, Asia, Bacterial Infections and Mycoses, Biosensors, Biotechnology, Fluorescent Biosensors, Health and Medicine, Nanotechnology, Fuzhou University. [Extracted from the article]

The sensor was constructed with a TAMRA-labeled DNA as probe, which could adsorb on polymer dots (Pdots) at acidic pH to produce TAMRA fluorescence at the excitation wavelength of Pdots via fluorescence resonance energy transfer (FRET). Keywords: Haikou; People's Republic of China; Asia; Betaproteobacteria; Biosensors; Biotechnology; Burkholderia; Burkholderia pseudomallei; Burkholderiaceae; Fluorescent Biosensors; Gram-Negative Aerobic Bacteria; Gram-Negative Aerobic Rods and Cocci; Gram-Negative Bacteria; Health and Medicine; Nanotechnology; Proteobacteria EN Haikou People's Republic of China Asia Betaproteobacteria Biosensors Biotechnology Burkholderia Burkholderia pseudomallei Burkholderiaceae Fluorescent Biosensors Gram-Negative Aerobic Bacteria Gram-Negative Aerobic Rods and Cocci Gram-Negative Bacteria Health and Medicine Nanotechnology Proteobacteria 720 720 1 05/22/23 20230526 NES 230526 2023 MAY 26 (NewsRx) -- By a News Reporter-Staff News Editor at Genomics & Genetics Weekly -- Investigators discuss new findings in Biosensors - Fluorescent Biosensors. [Extracted from the article]

Keywords: Wuhan; People's Republic of China; Asia; Biosensors; Biotechnology; Cancer; Fluorescent Biosensors; Health and Medicine; Lung Cancer; Lung Diseases and Conditions; Lung Neoplasms; Nanotechnology; Oncology EN Wuhan People's Republic of China Asia Biosensors Biotechnology Cancer Fluorescent Biosensors Health and Medicine Lung Cancer Lung Diseases and Conditions Lung Neoplasms Nanotechnology Oncology 748 748 1 05/15/23 20230516 NES 230516 2023 MAY 16 (NewsRx) -- By a News Reporter-Staff News Editor at Cancer Weekly -- New research on Biosensors is the subject of a report. For more information on this research see: Crispr/cas12a-based Fluorescence Biosensor for Detection of Exosomal Mir-21 Derived From Lung Cancer. [Extracted from the article]