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Roentgen therapy has its established place as a valuable palliative procedure in the treatment of human leukemias, lymphomas, and allied diseases. Its general and local effects in these disorders have been the subject of numerous reports by expert radiologists and hematologists. In the last decade radioactive isotopes and recently the nitrogen mustards have been added to the therapeutic arsenal against these diseases. The purpose of this presentation is to furnish an introduction to the papers2 on treatment with these new methods rather than to contribute anything new. As a basis for comparison with the results, complications, ad vantages, and limitations of the therapeutic use of these new compounds, we have reviewed 337 cases of blood dyscrasias treated by external irradiation in Billings Hospital (University of Chicago). Material The 337 cases represent the number of patients accepted for irradiation therapy from 1929 to 1945. The total number of patients with blood diseases seen in the clinics and in ...