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In this paper, we show a deep learning model for bot detection, named as DeBot, for industrial network traffic. DeBot uses a novel Cascade Forward Back Propagation Neural Network (CFBPNN) model with a subset of features using the Correlation-based Feature Selection (CFS) technique. A time series-based Nonlinear Auto-regressive Network with eXogenous inputs (NARX) technique analyzes the factors having a higher impact on the target variable and predict the behavioral pattern. To the best of our knowledge, we pioneer the use of optimal feature selection and integration with the cascading model of deep learning in bot detection of IIoTs. We conduct a thorough set of experiments on five popular bot datasets: NF-UNSW-NB15, NF-ToN-IoT, NF-BoT-IoT, NF-CSE-CIC-IDS2018, and ToN-IoT-Windows. We compare CFBPNN with other existing neural network models. We observe that CFBPNN in DeBot shows 100% accuracy in all the datasets with subset evaluation and obtains optimum F1-score and zero precision. [Display omitted] • We address the multi-layered network model with IIoT features to enable bot attack detection. • Our DeBot model evaluates the subset with optimal features with high impact on attack class and predict the risk factor. • We pioneer the implementation of time series-based Nonlinear Auto-Regressive eXogenous (NARX) model to predict the risk in the specified time gap. • We introduce a new cascading model with recurrent feature to preserve the relationship between input and output variables. [ABSTRACT FROM AUTHOR]