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The advancement of artificial intelligence (AI) has become a crucial element in autonomous cars. A well-designed AI architecture will be necessary to attain the full potential of autonomous vehicles and will significantly accelerate the development and deployment of autonomous cars in the transportation sector. Promising autonomous cars for innovating modern transportation systems are anticipated to address many long-standing transporting challenges related to congestion, safety, parking, and energy conservation. Choosing the optimal AI architecture for autonomous vehicles is a multi-attribute decision-making (MADM) dilemma, as it requires making a complicated decision while considering a number of attributes, and these attributes can have two-dimensional uncertainty as well as indiscernibility. Thus, in this framework, we developed a novel mathematical framework "complex intuitionistic fuzzy rough set" for tackling both two-dimensional uncertainties and indiscernibility. We also developed the elementary operations of the deduced complex intuitionistic fuzzy rough set. Moreover, we developed complex intuitionistic fuzzy rough (weighted averaging, ordered weighted averaging, weighted geometric, and ordered weighted geometric) aggregation operators. Afterward, we developed a method of MADM by employing the devised operators and investigated the case study "Selection of optimal AI architecture for autonomous vehicles" to reveal the practicability of the devised method of MADM. Finally, to reveal the dominance and supremacy of our proposed work, a benchmark dilemma was used for comparison with various prevailing techniques. [ABSTRACT FROM AUTHOR]

The kidney is an abdominal organ in the human body that supports filtering excess water and waste from the blood. Kidney diseases generally occur due to changes in certain supplements, medical conditions, obesity, and diet, which causes kidney function and ultimately leads to complications such as chronic kidney disease, kidney failure, and other renal disorders. Combining patient metadata with computed tomography (CT) images is essential to accurately and timely diagnosing such complications. Deep Neural Networks (DNNs) have transformed medical fields by providing high accuracy in complex tasks. However, the high computational cost of these models is a significant challenge, particularly in real-time applications. This paper proposed SpinalZFNet, a hybrid deep learning approach that integrates the architectural strengths of Spinal Network (SpinalNet) with the feature extraction capabilities of Zeiler and Fergus Network (ZFNet) to classify kidney disease accurately using CT images. This unique combination enhanced feature analysis, significantly improving classification accuracy while reducing the computational overhead. At first, the acquired CT images are pre-processed using a median filter, and the pre-processed image is segmented using Efficient Neural Network (ENet). Later, the images are augmented, and different features are extracted from the augmented CT images. The extracted features finally classify the kidney disease into normal, tumor, cyst, and stone using the proposed SpinalZFNet model. The SpinalZFNet outperformed other models, with 99.9% sensitivity, 99.5% specificity, precision 99.6%, 99.8% accuracy, and 99.7% F1-Score in classifying kidney disease. [ABSTRACT FROM AUTHOR]

Artificial intelligence (AI) frameworks are essential for development since they offer pre-built tools and libraries that speed up and simplify the production of AI models, leveraging symmetry to save time and effort. They guarantee effective computing by modifying code for particular hardware, facilitating quicker testing and deployment. The identification of a suitable and optimal AI framework for development is a multi-criteria decision-making (MCDM) dilemma, where the considered AI frameworks for development are evaluated by considering various criteria and these criteria may have dual aspects (positive and negative). Thus, in this manuscript, we diagnosed a technique of MCDM within the bipolar fuzzy set (BFS) for identification and selection of optimal AI framework for development. In this regard, we diagnosed probability aggregation operators (AOs) within BFS, such as probability bipolar fuzzy weighted averaging (P-BFWA), probability bipolar fuzzy ordered weighted averaging (P-BFOWA), immediate probability bipolar fuzzy ordered weighted averaging (IP-BFOWA), probability bipolar fuzzy weighted geometric (P-BFWG), probability bipolar fuzzy ordered weighted geometric (P-BFOWH), and immediate probability bipolar fuzzy ordered weighted geometric (IP-BFOWG) operators. The diagnosed technique would be based on these invented probably AOs. Afterward, in this manuscript, we took a case study and obtained the optimal AI framework for development by employing the diagnosed technique of MCDM. We also investigated the comparison of the devised theory with certain prevailing theories to reveal the dominance and significance of the devised theory. [ABSTRACT FROM AUTHOR]

A clinically important loss in a person's understanding, emotive power, or conduct is a symptom of a mental disorder. It generally occurs for genetic, psychological, and/or cognitive reasons and is accompanied by discomfort or limitationin significant functional areas. It can be handled using techniques similar to those used to treat chronic conditions (i.e., precautions, examination, medication, and recovery). Mental diseases take a variety of forms. Mental disorder is also identified as mental illness. The latter is a more usual phrase that incorporates psychological problems, psychosocial disorders, and (other) states of mind linked to considerable discomfort, operational limitations, or danger of loss of sanity. To rank the most prevalent types of mental disorders is a multi-attribute decision-making issue and thus this article aims to analyze the artificial intelligence-based evaluation of mental disorders and rank the most prevalent types of mental disorders. For this purpose, here we invent certain aggregation operators under the environment of the bipolar complex fuzzy set such as bipolar complex fuzzy Schweizer-Sklar prioritized weighted averaging, bipolar complex fuzzy Schweizer-Sklar prioritized ordered weighted averaging, bipolar complex fuzzy Schweizer-Sklar prioritized weighted geometric, bipolar complex fuzzy Schweizer-Sklar prioritized ordered weighted geometric operators. After that, we devise a procedure of decision-making for bipolar complex fuzzy information by employing the introduced operators and then take artificial data in the model of bipolar complex fuzzy set to rank the most prevalent types of mental disorders. Additionally, this article contains a comparative study of the introduced work with a few current works for exhibiting the priority and superiority of the introduced work. [ABSTRACT FROM AUTHOR]

Digital education is very important and valuable because it is a subpart of artificial intelligence, which is used in many real-life problems. Digital education is the modern utilization of digital techniques and tools during online purchasing, teaching, research, and learning and is often referred to as technology-enhanced learning or e-learning programs. Further, similarity measures (SM) and complex fuzzy (CF) logic are two different ideas that play a very valuable and dominant role in the environment of fuzzy decision theory. In this manuscript, we concentrate on utilizing different types of dice SM (D-SM) and generalized dice SM (GD-SM) in the environment of a CF set (CFS), called CF dice SM (CFD-SM), CF weighted dice SM (CFWD-SM), CF generalized dice SM (CFGD-SM), and CF weighted generalized dice SM (CFWGD-SM), and also derived associated outcomes. Furthermore, to evaluate or state the supremacy and effectiveness of the derived measures, we aim to evaluate the application of artificial intelligence in digital education under the consideration of derived measures for CF information and try to verify them with the help of several examples. Finally, with the help of examples, we illustrate the comparison between the presented and existing measures to show the supremacy and feasibility of the derived measures. [ABSTRACT FROM AUTHOR]

Artificial intelligence (AI) is a well-known and reliable technology that enables a machine to simulate human behavior. While the major theme of AI is to make a smart computer system that thinks like a human to solve awkward problems, machine learning allows a machine to automatically learn from past information without the need for explicit programming. In this analysis, we aim to derive the idea of Aczel–Alsina aggregation operators based on an intuitionistic fuzzy soft set. The initial stage was the discovery of the primary and critical Aczel–Alsina operational laws for intuitionistic fuzzy soft sets. Subsequently, we pioneer a range of applicable theories (set out below) and identify their essential characteristics and key results: intuitionistic fuzzy soft Aczel–Alsina weighted averaging; intuitionistic fuzzy soft Aczel–Alsina ordered weighted averaging; intuitionistic fuzzy soft Aczel–Alsina weighted geometric operators; and intuitionistic fuzzy soft Aczel–Alsina ordered weighted geometric operators. Additionally, by utilizing certain key information, including intuitionistic fuzzy soft Aczel–Alsina weighted averaging and intuitionistic fuzzy soft Aczel–Alsina weighted geometric operators, we also introduce the theory of the weighted aggregates sum product assessment method for intuitionistic fuzzy soft information. This paper also introduces a multi-attribute decision-making method, which is based on derived operators for intuitionistic fuzzy soft numbers and seeks to assess specific industrial problems using artificial intelligence or machine learning. Finally, to underline the value and reasonableness of the information described herein, we compare our obtained results with some pre-existing information in the field. This comparison is supported by a range of numerical examples to demonstrate the practicality of the invented theory. [ABSTRACT FROM AUTHOR]

Visual classification of pollen grains is crucial for various agricultural applications, particularly for the protection, monitoring, and tracking of flora to preserve the biome and maintain the quality of honey-based products. Traditionally, pollen grain classification has been performed by trained palynologists using a light microscope. Despite their wide range of applications, still tiresome and time-consuming methods are used. Artificial intelligence (AI) can be used to automate the pollen grain classification process. Recently, numerous AI-based techniques for classifying pollen grains have been proposed. However, there is still possibility for performance enhancement including processing time, memory size, and accuracy. In this study, an attention-guided pollen feature aggregation network (APFA-Net) based on deep feature aggregation and channel-wise attention is proposed. Three publicly available datasets, POLLEN73S, POLLEN23E, and Cretan pollen, having a total of 7362 images from 116 distinct pollen types are used for experiments. The proposed method shows F-measure values of 97.37 %, 97.66 %, and 98.39 % with POLLEN73S, POLLEN23E, and Cretan Pollen datasets, respectively. We confirm that our method outperforms existing state-of-the-art methods. [ABSTRACT FROM AUTHOR]

Renal cell carcinoma (RCC), which is the primary subtype of kidney cancer, is among the leading causes of cancer. Recent breakthroughs in computer vision, particularly deep learning, have revolutionized the analysis of histopathology images, thus providing potential solutions for tasks such as the grading of renal cell carcinoma. Nevertheless, the multitude of available neural network architectures and the absence of systematic evaluations render it challenging to identify optimal models and training configurations for distinct histopathology classification tasks. Hence, we propose a novel hybrid model that effectively combines the advantages of vision transformers and convolutional neural networks. The proposed method, which is named the renal cancer grading network, comprises two essential components: an adaptive convolution (AC) block and a dynamic attention (DA) block. The AC block emphasizes efficient feature extraction and spatial representation learning via intelligently designed convolutional operations. The DA block, which is constructed on the features of the AC block, is a crucial module for histopathology-image classification. It introduces a dynamic attention mechanism and employs a transformer encoder to refine learned representations. Experiments were conducted on four publicly available histopathology datasets: RCC dataset of Kasturba medical college (KMC), colorectal cancer histology (CRCH), break cancer histology (BreakHis) and colon cancer histopathology dataset (CCH). The proposed method demonstrated an accuracy of 90.62%, precision of 91.23%, recall of 90.63%, and a weighted harmonic mean of precision and recall (F1-score) of 90.92 on the KMC dataset. Similarly, the proposed method demonstrates consistent accuracy (weighted average F1-score of 99%) on the CRCH dataset, recognition rate of 88.30% on the BreakHis dataset, and an accuracy of 99.7% on CCH dataset. These results confirm that our method outperforms the state-of-the-art methods, thus demonstrating its effectiveness and robustness across various datasets. [ABSTRACT FROM AUTHOR]

Aggregation operators perform a valuable and significant role in various decision-making processes. Averaging and geometric aggregation operators are both used for capturing the interrelationships of the aggregated preferences, even if the preferences are independent. The purpose of this paper is to analyze the theory of complex linguistic fuzzy (CLF) sets and their important laws, such as algebraic laws, score values, and accuracy values, and to describe the relationship between the score and accuracy values with the help of their properties. Additionally, based on the proposed CLF information, we introduce the theory of CLF weighted averaging (CLFWA), CLF ordered weighted averaging (CLFOWA), CLF hybrid averaging (CLFHA), CLF weighted geometric (CLFWG), CLF ordered weighted geometric (CLFOWG), and CLF hybrid geometric (CLFHG) operators. The fundamental properties and some valuable results of these operators are evaluated, and their particular cases are described. Based on the presented operators, a technique for evaluating the "multi-attribute decision-making" (MADM) problems in the consideration of CLF sets is derived. The superiority of the derived technique is illustrated via a practical example, a set of experiments, and significant and qualitative comparisons. The illustration results indicate that the derived technique can be feasible and superior in evaluating CLF information. Further, it can be used for determining the interrelationships of attributes and the criteria of experts. Moreover, it is valuable and capable of evaluating the MADM problems using CLF numbers. [ABSTRACT FROM AUTHOR]

Pattern recognition is the computerized identification of shapes, designs, and reliabilities in information. It has applications in information compression, machine learning, statistical information analysis, signal processing, image analysis, information retrieval, bioinformatics, and computer graphics. Similarly, a medical diagnosis is a procedure to illustrate or identify diseases or disorders, which would account for a person's symptoms and signs. Moreover, to illustrate the relationship between any two pieces of intuitionistic hesitant fuzzy (IHF) information, the theory of generalized dice similarity (GDS) measures played an important and valuable role in the field of genuine life dilemmas. The main influence of GDS measures is that we can easily obtain a lot of measures by using different values of parameters, which is the main part of every measure, called DGS measures. The major influence of this theory is to utilize the well-known and valuable theory of dice similarity measures (DSMs) (four different types of DSMs) under the assumption of the IHF set (IHFS), because the IHFS covers the membership grade (MG) and non-membership grade (NMG) in the form of a finite subset of [0, 1], with the rule that the sum of the supremum of the duplet is limited to [0, 1]. Furthermore, we pioneered the main theory of generalized DSMs (GDSMs) computed based on IHFS, called the IHF dice similarity measure, IHF weighted dice similarity measure, IHF GDS measure, and IHF weighted GDS measure, and computed their special cases with the help of parameters. Additionally, to evaluate the proficiency and capability of pioneered measures, we analyzed two different types of applications based on constructed measures, called medical diagnosis and pattern recognition problems, to determine the supremacy and consistency of the presented approaches. Finally, based on practical application, we enhanced the worth of the evaluated measures with the help of a comparative analysis of proposed and existing measures. [ABSTRACT FROM AUTHOR]

Simple Summary: In this paper, we present an artificial Intelligence (AI) based automatic detection of mitoses in Uterine Leiomyosarcoma. Mitotic count is one of the important biomarkers in the field of histopathology. A dataset is also made available to research community which consists of images having moitotically active region. These regions are labeled by a trained AI expert in coordination with a senior histopathologist. Preliminary results show AI as promising solution for detection of mitotically active regions mitotic region in Uterine leiomyosarcoma cases and can be used as a second opinion system. Uterine leiomyosarcoma (ULMS) is the most common sarcoma of the uterus, It is aggressive and has poor prognosis. Its diagnosis is sometimes challenging owing to its resemblance by benign smooth muscle neoplasms of the uterus. Pathologists diagnose and grade leiomyosarcoma based on three standard criteria (i.e., mitosis count, necrosis, and nuclear atypia). Among these, mitosis count is the most important and challenging biomarker. In general, pathologists use the traditional manual counting method for the detection and counting of mitosis. This procedure is very time-consuming, tedious, and subjective. To overcome these challenges, artificial intelligence (AI) based methods have been developed that automatically detect mitosis. In this paper, we propose a new ULMS dataset and an AI-based approach for mitosis detection. We collected our dataset from a local medical facility in collaboration with highly trained pathologists. Preprocessing and annotations are performed using standard procedures, and a deep learning-based method is applied to provide baseline accuracies. The experimental results showed 0.7462 precision, 0.8981 recall, and 0.8151 F1-score. For research and development, the code and dataset have been made publicly available. [ABSTRACT FROM AUTHOR]

Tissue phenotyping of the tumor microenvironment has a decisive role in digital profiling of intra-tumor heterogeneity, epigenetics, and progression of cancer. Most of the existing methods for tissue phenotyping often rely on time-consuming and error-prone manual procedures. Recently, with the advent of advanced technologies, these procedures have been automated using artificial intelligence techniques. In this paper, a novel deep histology heterogeneous feature aggregation network (HHFA-Net) is proposed based on visual and semantic information fusion for the detection of tissue phenotypes in colorectal cancer (CRC). We adopted and tested various data augmentation techniques to avoid computationally expensive stain normalization procedures and handle limited and imbalanced data problems. Three publicly available datasets are used in the experiments: CRC tissue phenotyping (CRC-TP), CRC histology (CRCH), and colon cancer histology (CCH). The proposed HHFA-Net achieves higher accuracies than the state-of-the-art methods for tissue phenotyping in CRC histopathology images. [ABSTRACT FROM AUTHOR]

Duct cancer is a malignant disease with higher mortality rates in males than in females, emphasizing the need for early diagnosis to improve treatment outcomes. Although various imaging modalities such as magnetic resonance imaging (MRI) and computed tomography scan (CT-scan) have been used for pathological analysis, hyperspectral imaging stands out as a promising approach, especially when combined with deep learning techniques. Hyperspectral imaging provides detailed information on tissue composition and biochemical properties, enabling better distinction between cancerous and healthy tissues. Although previous research based on hyperspectral imaging shows high accuracy, no previous research has used a small amount of training data, despite this being the usual case in medical image applications. Therefore, we propose a multi-path residual attention network (MRA-Net) with chunked residual channel attention (CRCA), which is a novel deep learning model specifically designed to address the challenges posed by limited training data, with a particular focus on using hyperspectral images. By leveraging the unique spectral information provided by hyperspectral imaging, MRA-Net extracts distinctive features, enhancing its ability to differentiate between cancerous and healthy tissues. We conducted the training and validation of our model using a publicly accessible dataset, resulting in an accuracy of 84.31% and a weighted harmonic mean of precision and recall (F1 score) of 84.29%, demonstrating its state-of-the-art performance compared to existing methods. [ABSTRACT FROM AUTHOR]

In recent scenarios, we cannot ignore the importance of artificial intelligence in many fields like medical diagnosis, computer science, economics and agriculture, etc. In 1960, Schweizer and Sklar developed the concept of Schweizer-Sklar (SS) t-norm and t-conorm by incorporating a parameter which is more flexible and helpful in handling complex and unclear data. If we put parameter then the information of the Hamacher and Lukasiewicz t-norms is simply derived. The primary goal of this study is to develop the fundamental Schweizer-Sklar operational laws for bipolar fuzzy numbers. Additionally, we have defined the notion of bipolar fuzzy Schweizer-Sklar power average and bipolar fuzzy Schweizer-Sklar power geometric aggregation operators. Moreover, we have elaborated on the basic characteristics of these developed notions. We have initiated the algorithm to demonstrate the actual use of this work in artificial neural networking. We have also compared our work with some prevailing theories. [ABSTRACT FROM AUTHOR]

Surgical instrument segmentation plays a crucial role in robot-assisted surgery by furnishing essential information about instrument location and orientation. This information not only enhances surgical planning but also augments the precision and safety of procedures. Despite promising strides in recent research on surgical instrument segmentation, accuracy still faces obstacles due to local feature processing limitations, surgical environment complexity, and instrument morphological variability. To address these challenges, we introduced the channel-wise features fusion and recalibration network (CFFR-Net). This network utilizes a dual-stream mechanism, combining a context-guided block and dense block for feature extraction. The context-guided block captures a variety of contextual information by using different dilation rates. Additionally, CFFR-Net employs a fusion mechanism that harmonizes context-guided and dense streams. This integration, along with the inclusion of Squeeze-and-Excitation attention, enhances both the precision and robustness of semantic instrument segmentation. We performed experiments using two publicly available datasets for surgical instrument segmentation: the Kvasir-instrument and Endovis2017 datasets. The results of these experiments were highly encouraging, as our proposed model exhibited remarkable performance on both datasets compared to the state-of-the-art methods. On the Kvasir-instrument set, our model achieved a Dice score of 95.84% and mean intersection over union (mIOU) value of 92.40%. Similarly, on the Endovis2017 set, it obtained a Dice score of 95.47% and mIOU value of 93.02%. • A novel context-guided block is proposed for multi-context features extraction. • Coarse and fine features are extracted by proposed dual streams of dilated convolution. • Model capacity and efficiency are enhanced by using attention mechanism. • Diverse datasets of endoscopy and robot-assisted nephrectomy procedures are tested. • The trained model and code are publicly available via GitHub site. [ABSTRACT FROM AUTHOR]

Obstructive sleep apnea (OSA) is a breathing-related chronic disease in which the soft palate and tongue collapse and block the upper airway for at least 10 s during sleep. It can lead to many heart diseases such as hypertension, myocardial infarction, and coronary heart syndrome if not detected early. Artificial intelligence has facilitated the diagnosis of many diseases in healthcare. Polysomnography is a widely used but unpleasant, time-consuming, technically demanding, and financially expensive procedure to detect OSA. Some previous methods have detected OSA using time-domain information from an electrocardiogram (ECG), whereas others have used frequency-domain information. The limitations of these two approaches can be handled using the data's time–frequency representation. Nevertheless, there is room for enhancing the detection accuracy of OSA using the time–frequency representation approach. Therefore, we propose a novel technique that takes the ECG signal and detects R-peaks from the QRS complexes. Afterward, we interpolate those R-peaks by linear interpolation and get an interpolated-R signal. Then we magnify the interpolated-R signal corresponding to the apnea and normal frequency ranges. After magnification in the time domain, we transformed the magnified version into a scalogram. We also transformed the original one-minute ECG signal into a spectrogram after denoising. Overall, we used ECG signals to generate scalograms and spectrograms for 2 dimensional convolutional neural network (2D CNN) to classify obstructive sleep apnea. For apnea classification, we proposed a dual convolutional dual attention network (DCDA-Net) that includes a dual convolutionally modified inception module, a spatial attention module, and a channel attention module. Finally, we apply a support vector machine to the probability scores obtained from DCDA-Net based on the scalogram and spectrogram. Extensive experimental results using the open PhysioNet apnea ECG dataset confirm the effectiveness of our method in terms of accuracy and F1 score of 98% and 97.5%, respectively, which outperforms state-of-the-art methods. • We propose a magnification-based preprocessing method for a raw ECG segment. • Our DCDA-Net extracts grouped and focused features for sleep apnea classification. • We propose a ROI-based postprocessing method to better detect the apnea class. • The proposed DCDA-Net outperforms the state-of-the-art methods. [ABSTRACT FROM AUTHOR]

Digital technology refers to any technology that uses digital signals or electronic data to process, store, and transmit information. Some examples of digital technologies include social media platforms, cloud computing, artificial intelligence, virtual and augmented reality, and blockchain technology. Digital technology has the potential to play a significant role in achieving sustainable development goals by providing solutions for a wide range of environmental, social, and economic challenges. In this manuscript, we investigate digital technology implementation under sustainable development and would find which area of sustainable development is most in need of digital technology. Further, we investigate the operational laws based on Schweizer–Sklar t-norm and t-conorm and originate aggregation operators based on these deduced operational laws under the environment of bipolar complex fuzzy set that is bipolar complex fuzzy Schweizer–Sklar power averaging, bipolar complex fuzzy Schweizer–Sklar power weighted averaging, bipolar complex fuzzy Schweizer–Sklar power geometric and bipolar complex fuzzy Schweizer–Sklar power weighted geometric operators and then we deduce techniques of decision-making utilizing these originated operators. Afterward, we tackle a numerical example related to the digital technology implementation under sustainable development by considering artificial data and finding the area of sustainable development which is most in need of digital technology. Moreover, we reveal the impact of one of the digital technologies that are artificial intelligence in the field of healthcare and study a numerical example by considering hypothetical data by employing the originated technique of decision-making. At the last, we do a comparison of the deduced operators with numerous current operators to reveal the superiority and benefits of the deduced operators. • Investigated digital technology implementation under sustainable development. • Investigated the role and impact of AI in the field of healthcare. • Determined how AI influences healthcare via decision-making techniques. • Novel Schweizer–Sklar aggregation operators for bipolar complex fuzzy sets are initiated. • Used defined operators to handle healthcare issues based on digital technology. • Comparative study is initiated to prove the value of proposed techniques. [ABSTRACT FROM AUTHOR]

Background: Early recognition of prostheses before reoperation can reduce perioperative morbidity and mortality. Because of the intricacy of the shoulder biomechanics, accurate classification of implant models before surgery is fundamental for planning the correct medical procedure and setting apparatus for personalized medicine. Expert surgeons usually use X-ray images of prostheses to set the patient-specific apparatus. However, this subjective method is time-consuming and prone to errors. Method: As an alternative, artificial intelligence has played a vital role in orthopedic surgery and clinical decision-making for accurate prosthesis placement. In this study, three different deep learning-based frameworks are proposed to identify different types of shoulder implants in X-ray scans. We mainly propose an efficient ensemble network called the Inception Mobile Fully-Connected Convolutional Network (IMFC-Net), which is comprised of our two designed convolutional neural networks and a classifier. To evaluate the performance of the IMFC-Net and state-of-the-art models, experiments were performed with a public data set of 597 de-identified patients (597 shoulder implants). Moreover, to demonstrate the generalizability of IMFC-Net, experiments were performed with two augmentation techniques and without augmentation, in which our model ranked first, with a considerable difference from the comparison models. A gradient-weighted class activation map technique was also used to find distinct implant characteristics needed for IMFC-Net classification decisions. Results: The results confirmed that the proposed IMFC-Net model yielded an average accuracy of 89.09%, a precision rate of 89.54%, a recall rate of 86.57%, and an F1.score of 87.94%, which were higher than those of the comparison models. Conclusion: The proposed model is efficient and can minimize the revision complexities of implants. [ABSTRACT FROM AUTHOR]

Currently, the coronavirus disease 2019 (COVID19) pandemic has killed more than one million people worldwide. In the present outbreak, radiological imaging modalities such as computed tomography (CT) and X-rays are being used to diagnose this disease, particularly in the early stage. However, the assessment of radiographic images includes a subjective evaluation that is time-consuming and requires substantial clinical skills. Nevertheless, the recent evolution in artificial intelligence (AI) has further strengthened the ability of computer-aided diagnosis tools and supported medical professionals in making effective diagnostic decisions. Therefore, in this study, the strength of various AI algorithms was analyzed to diagnose COVID19 infection from large-scale radiographic datasets. Based on this analysis, a light-weighted deep network is proposed, which is the first ensemble design (based on MobileNet, ShuffleNet, and FCNet) in medical domain (particularly for COVID19 diagnosis) that encompasses the reduced number of trainable parameters (a total of 3.16 million parameters) and outperforms the various existing models. Moreover, the addition of a multilevel activation visualization layer in the proposed network further visualizes the lesion patterns as multilevel class activation maps (ML-CAMs) along with the diagnostic result (either COVID19 positive or negative). Such additional output as ML-CAMs provides a visual insight of the computer decision and may assist radiologists in validating it, particularly in uncertain situations Additionally, a novel hierarchical training procedure was adopted to perform the training of the proposed network. It proceeds the network training by the adaptive number of epochs based on the validation dataset rather than using the fixed number of epochs. The quantitative results show the better performance of the proposed training method over the conventional end-to-end training procedure. A large collection of CT-scan and X-ray datasets (based on six publicly available datasets) was used to evaluate the performance of the proposed model and other baseline methods. The experimental results of the proposed network exhibit a promising performance in terms of diagnostic decision. An average F1 score (F1) of 94.60% and 95.94% and area under the curve (AUC) of 97.50% and 97.99% are achieved for the CT-scan and X-ray datasets, respectively. Finally, the detailed comparative analysis reveals that the proposed model outperforms the various state-of-the-art methods in terms of both quantitative and computational performance. • A novel interpretable computer-aided framework to diagnose COVID19 infection. • Promising performance over the various state-of-the-art methods. • Hierarchical training procedure performs the optimal training of proposed network. • ML-CAMs provides visual insight of the computer decision. • Proposed trained model and data splitting information are publicly available. [ABSTRACT FROM AUTHOR]

Accurate nuclear segmentation in histopathology images plays a key role in digital pathology. It is considered a prerequisite for the determination of cell phenotype, nuclear morphometrics, cell classification, and the grading and prognosis of cancer. However, it is a very challenging task because of the different types of nuclei, large intraclass variations, and diverse cell morphologies. Consequently, the manual inspection of such images under high-resolution microscopes is tedious and time-consuming. Alternatively, artificial intelligence (AI)-based automated techniques, which are fast and robust, and require less human effort, can be used. Recently, several AI-based nuclear segmentation techniques have been proposed. They have shown a significant performance improvement for this task, but there is room for further improvement. Thus, we propose an AI-based nuclear segmentation technique in which we adopt a new nuclear segmentation network empowered by residual skip connections to address this issue. Experiments were performed on two publicly available datasets: (1) The Cancer Genome Atlas (TCGA), and (2) Triple-Negative Breast Cancer (TNBC). The results show that our proposed technique achieves an aggregated Jaccard index (AJI) of 0.6794, Dice coefficient of 0.8084, and F1-measure of 0.8547 on TCGA dataset, and an AJI of 0.7332, Dice coefficient of 0.8441, precision of 0.8352, recall of 0.8306, and F1-measure of 0.8329 on the TNBC dataset. These values are higher than those of the state-of-the-art methods. [ABSTRACT FROM AUTHOR]

Background: The early diagnosis of various gastrointestinal diseases can lead to effective treatment and reduce the risk of many life-threatening conditions. Unfortunately, various small gastrointestinal lesions are undetectable during early-stage examination by medical experts. In previous studies, various deep learning-based computer-aided diagnosis tools have been used to make a significant contribution to the effective diagnosis and treatment of gastrointestinal diseases. However, most of these methods were designed to detect a limited number of gastrointestinal diseases, such as polyps, tumors, or cancers, in a specific part of the human gastrointestinal tract.Objective: This study aimed to develop a comprehensive computer-aided diagnosis tool to assist medical experts in diagnosing various types of gastrointestinal diseases.Methods: Our proposed framework comprises a deep learning-based classification network followed by a retrieval method. In the first step, the classification network predicts the disease type for the current medical condition. Then, the retrieval part of the framework shows the relevant cases (endoscopic images) from the previous database. These past cases help the medical expert validate the current computer prediction subjectively, which ultimately results in better diagnosis and treatment.Results: All the experiments were performed using 2 endoscopic data sets with a total of 52,471 frames and 37 different classes. The optimal performances obtained by our proposed method in accuracy, F1 score, mean average precision, and mean average recall were 96.19%, 96.99%, 98.18%, and 95.86%, respectively. The overall performance of our proposed diagnostic framework substantially outperformed state-of-the-art methods.Conclusions: This study provides a comprehensive computer-aided diagnosis framework for identifying various types of gastrointestinal diseases. The results show the superiority of our proposed method over various other recent methods and illustrate its potential for clinical diagnosis and treatment. Our proposed network can be applicable to other classification domains in medical imaging, such as computed tomography scans, magnetic resonance imaging, and ultrasound sequences. [ABSTRACT FROM AUTHOR]

Breast cancer is the leading cause of mortality in women. Early diagnosis of breast cancer can reduce the mortality rate. In the diagnosis, the mitotic cell count is an important biomarker for predicting the aggressiveness, prognosis, and grade of breast cancer. In general, pathologists manually examine histopathology images under high-resolution microscopes for the detection of mitotic cells. However, because of the minute differences between the mitotic and normal cells, this process is tiresome, time-consuming, and subjective. To overcome these challenges, artificial-intelligence-based (AI-based) techniques have been developed which automatically detect mitotic cells in the histopathology images. Such AI techniques accelerate the diagnosis and can be used as a second-opinion system for a medical doctor. Previously, conventional image-processing techniques were used for the detection of mitotic cells, which have low accuracy and high computational cost. Therefore, a number of deep-learning techniques that demonstrate outstanding performance and low computational cost were recently developed; however, they still require improvement in terms of accuracy and reliability. Therefore, we present a multistage mitotic-cell-detection method based on Faster region convolutional neural network (Faster R-CNN) and deep CNNs. Two open datasets (international conference on pattern recognition (ICPR) 2012 and ICPR 2014 (MITOS-ATYPIA-14)) of breast cancer histopathology were used in our experiments. The experimental results showed that our method achieves the state-of-the-art results of 0.876 precision, 0.841 recall, and 0.858 F1-measure for the ICPR 2012 dataset, and 0.848 precision, 0.583 recall, and 0.691 F1-measure for the ICPR 2014 dataset, which were higher than those obtained using previous methods. Moreover, we tested the generalization capability of our technique by testing on the tumor proliferation assessment challenge 2016 (TUPAC16) dataset and found that our technique also performs well in a cross-dataset experiment which proved the generalization capability of our proposed technique. [ABSTRACT FROM AUTHOR]

Glaucoma is one of the most common chronic diseases that may lead to irreversible vision loss. The number of patients with permanent vision loss due to glaucoma is expected to increase at an alarming rate in the near future. A considerable amount of research is being conducted on computer-aided diagnosis for glaucoma. Segmentation of the optic cup (OC) and optic disc (OD) is usually performed to distinguish glaucomatous and non-glaucomatous cases in retinal fundus images. However, the OC boundaries are quite non-distinctive; consequently, the accurate segmentation of the OC is substantially challenging, and the OD segmentation performance also needs to be improved. To overcome this problem, we propose two networks, separable linked segmentation network (SLS-Net) and separable linked segmentation residual network (SLSR-Net), for accurate pixel-wise segmentation of the OC and OD. In SLS-Net and SLSR-Net, a large final feature map can be maintained in our networks, which enhances the OC and OD segmentation performance by minimizing the spatial information loss. SLSR-Net employs external residual connections for feature empowerment. Both proposed networks comprise a separable convolutional link to enhance computational efficiency and reduce the cost of network. Even with a few trainable parameters, the proposed architecture is capable of providing high segmentation accuracy. The segmentation performances of the proposed networks were evaluated on four publicly available retinal fundus image datasets: Drishti-GS, REFUGE, Rim-One-r3, and Drions-DB which confirmed that our networks outperformed the state-of-the-art segmentation architectures. [ABSTRACT FROM AUTHOR]