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A theory, called the Kinematic Theory of Rapid Human Movement, was proposed a few years ago to analyze rapid human movements, called the Kinematic Theory of Rapid Human Movements, based on a delta-lognormal equation that globally describes the basic properties of the velocity profiles of an end-effector using seven parameters. This realistic model has been very useful for proposing original solutions to various pattern recognition problems (signature segmentation and verification, handwriting analysis and synthesis, etc.). Most of these applications rely on the use of an efficient algorithm to extract the delta-lognormal parameters from real data with the best possible fit. In this paper, we compare two such algorithms: a deterministic one, based on nonlinear regression, and a Breeder Genetic algorithm. The performance of these two algorithms and of their combinations are compared using the same artificial database, composed of analytical delta-lognormal profiles and their noisy versions (20 dB SNR). In the free-noise case, the analysis of the experimental results shows that the deterministic approach leads to better results than the evolutionary one, while under the extremely noisy conditions selected, the evolutionary approach seems to be less sensitive to noise, but is nevertheless less successful than the deterministic search. [ABSTRACT FROM AUTHOR]

Background: The use of Artificial Intelligence (AI) systems for automatic diagnoses is increasingly in the clinical field, being a useful support for the identification of several diseases. Nonetheless, the acceptance of AI-based diagnoses by the physicians is hampered by the black-box approach implemented by most performing systems, which do not clearly state the classification rules adopted. Methods: In this framework we propose a classification method based on a Cartesian Genetic Programming (CGP) approach, which allows for the automatic identification of the presence of the disease, and concurrently, provides the explicit classification model used by the system. Results: The proposed approach has been evaluated on the publicly available HandPD dataset, which contains handwriting samples drawn by Parkinson's disease patients and healthy controls. We show that our approach compares favorably with state-of-the-art methods, and more importantly, allows the physician to identify an explicit model relevant for the diagnosis based on the most informative subset of features. Conclusion: The obtained results suggest that the proposed approach is particularly appealing in that, starting from the explicit model, it allows the physicians to derive a set of guidelines for defining novel testing protocols and intervention strategies. [ABSTRACT FROM AUTHOR]