1. [Lectin arthritis--a new arthritis model].
- Author
-
Thoss VK, Raabe G, and Muller P
- Subjects
- Animals, Disease Models, Animal, Female, Granulocytes, Knee Joint pathology, Lymphocytes, Macrophages, Plasma Cells, Rabbits, Arthritis chemically induced, Lectins
- Abstract
By single intraarticular injection of lectin from Lens culinaris in nosenitized rabbits acute and chronic arthritis was produced. By use of fluoresceinisothiocyanate-labelled lectin binding of lectin could be demonstrated in the connective tissue of joint capsule for 4 weeks. The morphological features of lectin-arthritis were described. The results are discussed with respect to the pathogenesis of the arthritis.
- Published
- 1976