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Introduction: Osteoarthritis (OA) or arthrosis represents an inflammatory disease of joints that develops as a result of interaction of mechanical and biological parameters. With disease development, degenerative changes on joint cartilage can be noticeable that affect and cause pathological changes on other parts of a joint resulting in pain and dysfunction of a joint. A. E. Garrod in 1907 described osteoarthritis as a special clinical entity and separated it from a rheumatoid arthritis. OA is characterized with loss of a joint cartilage, development of new bone tissue under affected cartilage (subchondral bone) and development of osteophytes on joint edge. First sign of a disease is pain after period of relaxation that slowly intensifies., Material and Methods: In this paper, 40 patients have been analyzed with clinical and radiological signs of OA of the knee joint. Radiological classification was done by Ahlback's classification., Results: In our study female gender was more affected with average age of 63 years. On Ahlback classification, grade II was represented the most. Comparison between clinical and radiological signs showed that there was no significant difference between established grade of OA. Wide spectrum of visible radiological osteoarthritis changes on joints is in correlation with the age of examinees., Competing Interests: • Conflict of interest: none declared.