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Start Over Author "Cen, Jinghe" Topic aromatic compounds
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1. Pd-catalyzed oxidative cross-coupling of imidazo[1,2-a]pyridine with arenes.

Author

Wang, Shaohua, Liu, Wenjie, Cen, Jinghe, Liao, Jinqiang, Huang, Jianping, and Zhan, Haiying

Subjects
*PALLADIUM catalysts, *OXIDATION, *COUPLING reactions (Chemistry), *PYRIDINE, *AROMATIC compounds, *REGIOSELECTIVITY (Chemistry)
Abstract

Abstract: A facile method for direct Pd(OAc)2-catalyzed oxidative cross-coupling of unactivated imidazo[1,2-a]pyridine with simple arenes has been developed. The reaction shows good reaction efficiency, high regioselectivity, and good functional-group compatibility. This approach provides a useful protocol for the preparation of imidazo[1,2-a]pyridine–arene structure of interest in biological and pharmaceutical materials. [Copyright &y& Elsevier]

Published
2014
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