Search

Your search keyword '"Maria Afentakis"' showing total 1 results
Start Over Author "Maria Afentakis" Topic aromatase inhibitors
1 results on '"Maria Afentakis"'

1. Early Enrichment of ESR1 Mutations and the Impact on Gene Expression in Presurgical Primary Breast Cancer Treated with Aromatase Inhibitors

Author

Mariana Ferreira, Leal, Ben P, Haynes, Eugene, Schuster, Belinda, Yeo, Maria, Afentakis, Lila, Zabaglo, Vera, Martins, Richard, Buus, Andrew, Dodson, Maggie C U, Cheang, Ian E, Smith, Lesley-Ann, Martin, and Mitch, Dowsett

Subjects
Aged, 80 and over, Aromatase Inhibitors, Gene Expression Profiling, Estrogen Receptor alpha, Breast Neoplasms, Middle Aged, Immunohistochemistry, Gene Expression Regulation, Neoplastic, Treatment Outcome, Mutation, Biomarkers, Tumor, Humans, Female, Receptors, Progesterone, Aged, Neoplasm Staging
Abstract

To investigate the presence ofWe evaluated ER, progesterone receptor, and Ki67 by immunostaining,Cell proliferation and estrogen-regulated genes (ERG) remained suppressed in most tumors indicative of persistent response to NAI. Enrichment ofLigand-independent ER signaling, as a result of

Published
2019

Catalog

Books, media, physical & digital resources
See catalog results