1. Peripheral membrane proteins modulate stress tolerance by safeguarding cellulose synthases
- Author
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Christopher Kesten, Álvaro García-Moreno, Vítor Amorim-Silva, Alexandra Menna, Araceli G. Castillo, Francisco Percio, Laia Armengot, Noemi Ruiz-Lopez, Yvon Jaillais, Clara Sánchez-Rodríguez, Miguel A. Botella, Instituto de Hortofruticultura Subtropical y Mediterranea 'La Mayora' (IHSM), Universidad de Málaga [Málaga] = University of Málaga [Málaga]-Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Reproduction et développement des plantes (RDP), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Department of Biology [ETH Zürich] (D-BIOL), and Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] (ETH Zürich)
- Subjects
Multidisciplinary ,Arabidopsis Proteins ,[SDV]Life Sciences [q-bio] ,Cell Membrane ,Arabidopsis ,Membrane Proteins ,Cellulose ,Microtubules - Abstract
Controlled primary cell wall remodeling allows plant growth under stressful conditions, but how these changes are conveyed to adjust cellulose synthesis is not understood. Here, we identify the TETRATRICOPEPTIDE THIOREDOXIN-LIKE (TTL) proteins as new members of the cellulose synthase complex (CSC) and describe their unique and hitherto unknown dynamic association with the CSC under cellulose-deficient conditions. We find that TTLs are essential for maintaining cellulose synthesis under high-salinity conditions, establishing a stress-resilient cortical microtubule array, and stabilizing CSCs at the plasma membrane. To fulfill these functions, TTLs interact with CELLULOSE SYNTHASE 1 (CESA1) and engage with cortical microtubules to promote their polymerization. We propose that TTLs function as bridges connecting stress perception with dynamic regulation of cellulose biosynthesis at the plasma membrane., Science Advances, 8 (46), ISSN:2375-2548
- Published
- 2022
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