2,415 results
Search Results
2. Validation of a new hand-held electronic appetite rating system against the pen and paper method.
- Author
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Almiron-Roig E, Green H, Virgili R, Aeschlimann JM, Moser M, and Erkner A
- Subjects
- Adult, Eating physiology, Eating psychology, Female, Humans, Hunger, Male, Pain Measurement, Reproducibility of Results, Satiation, Sensitivity and Specificity, Sensory Thresholds, Surveys and Questionnaires, Thirst, Appetite physiology, Electronics, Paper
- Abstract
This study describes the validation of a new electronic appetite rating system, and a statistical variance model for visual analogue scale (VAS) research. Thirty volunteers rated hunger, fullness, desire to eat, prospective intake, thirst and liking on 100mm paper VAS and on 70 mm electronic VAS presented on a Dell Pocket PC, after consuming breakfast, in a repeated trial. The electronic method was comparable in relative accuracy and reproducibility to the paper method, with weak differences between tests (within-subject SD < or =14 mm). The data obtained were used to generate a model for VAS data variability.
- Published
- 2009
- Full Text
- View/download PDF
3. Comparison of the traditional paper visual analogue scale questionnaire with an Apple Newton electronic appetite rating system (EARS) in free living subjects feeding ad libitum.
- Author
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Stratton RJ, Stubbs RJ, Hughes D, King N, Blundell JE, and Elia M
- Subjects
- Adult, Consumer Behavior, Cross-Over Studies, Female, Humans, Hunger, Male, Sensitivity and Specificity, Appetite, Microcomputers, Paper, Surveys and Questionnaires
- Abstract
Objective: Assessing the value of a newly developed electronic visual analogue scale questionnaire (Apple Newton Message Pad) with the traditional paper method for appetite rating., Design: In a random, crossover design, subjects completed both electronic and paper questionnaires to compare results obtained by the two methods; individual methods were completed consecutively to assess test-retest reliability; preference was established using a questionnaire., Setting/subjects: Healthy, free-living adults were studied for comparison of methods (n = 12), test-retest reliability (n = 8) and preference (n = 13)., Intervention: Visual analogue scales were completed each waking hour to assess appetite. Preference was assessed after both methods were completed., Results: There was no significant difference in the hourly results obtained by the paper and electronic methods for 'desire to eat', 'how much can you eat now', 'urge to eat' and 'preoccupation with thoughts of food'. Small differences in 'hunger' and 'fullness' ratings were noted (approximately 5% mean difference between methods, P < 0.05), but patterns of change and sensitivity for these and all other parameters remained similar for both methods across the visual analogue scale. Test-retest reliability demonstrated was similar for both methods. Seven (54%) subjects preferred to use the paper questionnaire, five (38%) the electronic method and one (8%) had no preference., Conclusions: The electronic Apple Newton questionnaire is as sensitive and reliable as the paper method, has the advantage that it automatically records the time of data acquisition and data collection and processing are more efficient for the researcher. The two methods should not be used interchangeably.
- Published
- 1998
- Full Text
- View/download PDF
4. Oral frailty, appetite and dietary variety in late-stage older adults: A cross-sectional study (the STudy of lAte-stage oldeR adulTs in Tottori; START Tottori).
- Author
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Nakagawa S, Miura K, Arai E, Taira K, Watanabe Y, Shirobe M, Motokawa K, Ohara Y, Iwasaki M, Hirano H, Ono T, Adachi A, Watanabe T, and Yamazaki Y
- Subjects
- Humans, Cross-Sectional Studies, Aged, Male, Female, Japan epidemiology, Aged, 80 and over, Surveys and Questionnaires, Diet, Malnutrition epidemiology, Oral Health, Nutrition Assessment, Nutritional Status, Appetite physiology, Frailty epidemiology, Geriatric Assessment methods, Frail Elderly
- Abstract
Aim: Efforts to combat frailty and preserve good health in older adults have highlighted oral frailty as an early indicator of overall frailty. Individuals showing oral frailty are at an elevated risk of insufficient nutritional intake compared with those without oral frailty; however, underlying mechanisms remain poorly explored. In this cross-sectional study, we aimed to examine the link between oral frailty and undernutrition, especially regarding poor appetite and low dietary diversity., Methods: The analysis included 2727 late-stage older adults (mean age 79.9 ± 4.3 years) who underwent dental checkups in a prefecture in Japan from 2016 to 2020. The examination involved a questionnaire survey (covering basic information, frailty screening index, appetite index: Simplified Nutritional Appetite Questionnaire; and dietary variety: Dietary Variety Score) and a measurement survey (including intraoral confirmation, oral diadochokinesis and masticatory efficiency test). Individuals with three or more indications of poor oral function, identified through oral function assessment, were defined as showing oral frailty. Binomial logistic regression and path analyses examined associations among oral frailty, Simplified Nutritional Appetite Questionnaire and Dietary Variety Score., Results: Among those analyzed, 1208 (44.3%) participants were categorized into the oral frailty group. Binomial logistic regression analysis showed that Simplified Nutritional Appetite Questionnaire (odds ratio for oral frailty per 1-point increase 0.88, 95% confidence interval 0.84-0.93) and Dietary Variety Score (odds ratio 0.95, 95% confidence interval 0.92-0.98) were significantly associated with oral frailty. The path analysis showed individual associations between each examined factor., Conclusions: Oral frailty was associated with decreased appetite and dietary variety in late-stage older adults. Geriatr Gerontol Int 2024; 24: 626-633., (© 2024 Japan Geriatrics Society.)
- Published
- 2024
- Full Text
- View/download PDF
5. Agreement between paper and pen visual analogue scales and a wristwatch-based electronic appetite rating system (PRO-Diary©), for continuous monitoring of free-living subjective appetite sensations in 7-10 year old children.
- Author
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Rumbold PL, Dodd-Reynolds CJ, and Stevenson E
- Subjects
- Child, Eating, Electronics, Female, Humans, Hunger, Male, Satiation, Sensation physiology, Surveys and Questionnaires, Appetite physiology, Monitoring, Physiologic instrumentation
- Abstract
Electronic capture of free-living subjective appetite data can provide a more reliable alternative to traditional pen and paper visual analogue scales (P&P VAS), whilst reducing researcher workload. Consequently, the aim of this study was to explore the agreement between P&P VAS and a wristwatch-based electronic appetite rating system known as the PRO-Diary© technique, for monitoring free-living appetite sensations in 7-10 year old children. On one occasion, using a within-subject design, the 12 children (n=6 boys; n=6 girls) recorded their subjective appetite (hunger, prospective food consumption, and fullness), at two time points before lunch (11:30 and 12:00) and every 60 min thereafter until 21:00. The agreement between the P&P VAS and PRO-Diary© technique was explored using 95% limits of agreement and 95% confidence intervals (95% CI) calculated using the Bland and Altman (1986) technique. For hunger, prospective food consumption and fullness, the 95% limits of agreement were -1±25 mm (95% CI: lower limit -8mm; upper limit +6mm), 0±21 mm (95% CI: lower limit -6mm; upper limit +6mm) and -6±24 mm (95% CI: lower limit -14 mm; upper limit +1mm), respectively. Given the advantages associated with electronic data capture (inexpensive; integrated alarm; data easily downloaded), we conclude that the PRO-Diary© technique is an equivalent method to employ when continuously monitoring free-living appetite sensations in 7-10 year old children, but should not be used interchangeably with P&P VAS., (Copyright © 2013 Elsevier Ltd. All rights reserved.)
- Published
- 2013
- Full Text
- View/download PDF
6. Assessment of subjective appetite sensations in hemodialysis patients. Agreement and feasibility between traditional paper and pen and a novel electronic appetite rating system.
- Author
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Zabel R, Ash S, Bauer J, and King N
- Subjects
- Adult, Aged, Female, Humans, Male, Middle Aged, Reproducibility of Results, Appetite, Hunger, Renal Dialysis, Satiety Response
- Abstract
The aim of this study was to assess the agreement between a novel Electronic Appetite Rating System (EARS) and traditional paper and pen visual analog scales (VASs) in a clinical population. 28 hemodialysis patients (mean age 61+/-17 years, 50% male, median dialysis vintage 19.5(4-101) months) were asked to rate their subjective sensations of hunger, fullness and desire to eat on VAS using both methods. The mean (S.D.) bias ranged from 2.6(16.6)mm to 6.2(15.7)mm which indicated that the two methods did not agree. Patients preferred the paper and pen method compared with the EARS. Either method would be suitable to use in a clinical population; however, it would be inappropriate to use the methods interchangeably.
- Published
- 2009
- Full Text
- View/download PDF
7. Introduction to four papers on Curt Richter and analysis of his scientific practice.
- Author
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Smith GP
- Subjects
- Animals, Biomedical Research history, History, 19th Century, History, 20th Century, Nutritional Physiological Phenomena, Physiology history, Appetite
- Abstract
Curt Richter was one of the founders of our field. He did outstanding research for over 60 years. Richter did fundamental work in appetite for food and minerals in the 1930s and discovered the homeostatic functions of ingestive behavior. This paper introduces four papers on specific topics of his work by contemporaneous experts. Each of the papers reviews Richter's experiments and then shows how the problem developed since he left it. The papers demonstrate that providing the historical basis for contemporary science is not only instructive, it is also heuristic for the science waiting to be done. In addition to introducing the four papers, I analyze the scientific ideas, values, and men that influenced Richter's scientific practice. I conclude that Claude Bernard, Walter Cannon, Francois Magendie, and Maurice Arthus were important for Richter's scientific ideas and values, but it was the joy of research that explains his experimental success for over 60 years.
- Published
- 2007
- Full Text
- View/download PDF
8. Testing the measurement equivalence of paper and interactive voice response system versions of the EORTC QLQ-C30
- Author
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Lundy, J. Jason, Coons, Stephen Joel, and Aaronson, Neil K.
- Published
- 2014
9. Comments to the editor concerning the paper entitled "Histidine suppresses food intake through its conversion into neuronal histamine" by Yoshimatsu et al.
- Author
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Henkin RI
- Subjects
- Animals, Enzyme Inhibitors pharmacology, Histidine pharmacokinetics, Histidine Decarboxylase antagonists & inhibitors, Humans, Methylhistidines pharmacology, Neurons metabolism, Serum Albumin metabolism, Zinc metabolism, Appetite drug effects, Dysgeusia chemically induced, Eating drug effects, Histamine metabolism, Histidine pharmacology, Zinc deficiency
- Published
- 2002
- Full Text
- View/download PDF
10. Introduction to papers presented at: the twenty fifth anniversary symposium of the Columbia University Seminar on Appetitive Behavior.
- Author
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Kissileff HR
- Subjects
- Humans, Appetite, Feeding Behavior
- Published
- 1997
- Full Text
- View/download PDF
11. "A Want of Taste": Carnivorous Desire and Sexual Politics in "The Pickwick Papers"
- Author
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STERN, KIMBERLY J.
- Published
- 2012
12. Broadsides at the Board: Collations of Pickwick Papers and Oliver Twist
- Author
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Houston, Gail Turley
- Published
- 1991
- Full Text
- View/download PDF
13. The evaluation of an electronic visual analogue scale system for appetite and mood.
- Author
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Whybrow S, Stephen JR, and Stubbs RJ
- Subjects
- Adult, Cross-Over Studies, Female, Humans, Male, Paper, Sensitivity and Specificity, Affect, Appetite, Microcomputers, Surveys and Questionnaires standards
- Abstract
Our objective was to evaluate a new electronic visual analogue scale (VAS) system for logging subjective motivation to eat ratings. In total, 10 men and 10 women completed both electronic and traditional pen and paper versions of the questionnaire every hour of the waking day. Subjects consumed a standard medium-fat diet, which was fixed at 1.6.BMR. Correlation coefficients for scores obtained by both methods were significant for all questions, with R(2) values ranging from 67 to 87%. However, Bland and Altman plots and paired t-tests identified significant bias between the two methods for five of the nine individual questions. These were questions that tended to be scored more towards the ends of the VAS. The new electronic VAS produces comparable, but not interchangeable, results to the traditional pen and paper method in the study of appetite and mood, while offering advantages of improved reliability in data collection.
- Published
- 2006
- Full Text
- View/download PDF
14. [COLOR REACTIONS FOR THE IDENTIFICATION OF SOME DRUGS WITH CENTRAL STIMULATING AND-OR APPETITE CONTROLLING PROPERTIES ON THE PAPER CHROMATOGRAM].
- Author
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FREUNDT KJ and SCHWINGER G
- Subjects
- Antidepressive Agents, Appetite, Appetite Depressants, Ascorbic Acid, Central Nervous System Stimulants, Chemistry, Pharmaceutical, Chromatography, Ephedrine, Folic Acid, Research, Sympathomimetics, Vitamin B Complex
- Published
- 1964
15. Appetite and its association with mortality in patients with advanced cancer - a Post-hoc Analysis from the Palliative D-study.
- Author
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Goodrose-Flores C, Bonn SE, Klasson C, Frankling MH, Lagerros YT, and Björkhem-Bergman L
- Subjects
- Male, Humans, Female, Palliative Care, Albumins therapeutic use, Fatigue, Appetite, Neoplasms complications
- Abstract
Background: Loss of appetite is a common nutrition symptom in patients with cancer. Understanding the trajectory of appetite could be of clinical use for prognostication in palliative cancer care. Our primary aim was to explore the association between self-assessed appetite and mortality in patients suffering from advanced cancer. Secondary aims included the relation between fatigue, albumin levels and CRP/albumin ratio and mortality. We also aimed to study potential sex-differences in the associations., Methods: Post-hoc analyses were performed using data from the Palliative D-study comprising 530 patients with cancer admitted to palliative care. Appetite and fatigue were assessed with the Edmonton Symptom Assessment System (ESAS). Cox proportional hazards models were used to calculate Hazard ratios (HR) with 95% confidence intervals (CI) for exposures of appetite, fatigue, albumin and CRP/albumin ratio, and time from study inclusion to death or censoring. Analyses were also performed stratified by sex., Results: The follow-up time ranged between 7 to 1420 days. Moderate and poor appetite were significantly associated with a higher mortality rate compared to reporting a good appetite; HR 1.44 (95%CI: 1.16-1.79) and HR 1.78 (95%CI: 1.39-2.29), respectively. A higher mortality rate was also seen among participants reporting severe fatigue compared to those reporting no fatigue; HR 1.84 (95%CI:1.43-2.36). Participants with low albumin levels (< 25 g/L) and those in the highest tertile of CRP/albumin ratio, had higher mortality rates, HR 5.35 (95%CI:3.75-7.63) and HR 2.66 (95%CI:212-3.35), compared to participants with high albumin levels (> 36 g/L) and those in lowest tertile of CRP/albumin ratio. These associations were more pronounced in men than in women., Conclusion: Poor appetite, severe fatigue, low albumin level and a high CRP/albumin ratio were associated with increased mortality rates among patients with advanced cancer. All these variables might be clinically useful for prognostication in palliative cancer care., Trial Registration: Clinicaltrial.gov. Identifier: NCT03038516;31, January 2017., (© 2023. BioMed Central Ltd., part of Springer Nature.)
- Published
- 2023
- Full Text
- View/download PDF
16. Bank Risk Appetite Communication and Risk Taking: The Key Role of Integrated Reports.
- Author
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Mio C, Agostini M, and Panfilo S
- Subjects
- Risk-Taking, Rivers, Appetite, Disclosure
- Abstract
This article investigates whether qualitative information provided by banks about risk appetite (RA) sheds substantive insight on their effective risk taking (RT) and whether this latter in turn affects RA disclosure, as well as the role played by specific types of banks' reports (i.e., integrated report, annual report, Pillar 3 report) on such relations. Using a sample of 134 reports representing 52 banks, a generalized structural equation model is applied. The article hypothesizes and empirically finds a reciprocal relation between RA disclosure and banks' RT. More specifically, in line with agency theory, the analysis displays a predominance of the inverse relation according to which banks showing higher RT provide greater disclosure. In addition, RT is found to play a mediator role between the adoption of a specific type of report-the integrated report-and RA disclosure, independently of the context in which the banks operate. Results also highlight that RT in banks adopting an integrated report is lower than the one of matched banks. Overall, this study extends risk science by complementing the literature stream on banks' accounting discretion and risk disclosure, supporting the impact of market discipline in promoting new forms of corporate reporting. Results indeed emphasize the key role of integrated reporting on RT, suggesting that integrated logic should be strengthened by policy makers to curb banks' excessive RT and leading them to provide substantive disclosure., (© 2021 Society for Risk Analysis.)
- Published
- 2022
- Full Text
- View/download PDF
17. Thirst: neuroendocrine regulation in mammals.
- Author
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Todini L and Fantuz F
- Subjects
- Animals, Mammals, Water, Thirst physiology, Appetite physiology
- Abstract
Animals can sense their changing internal needs and then generate specific physiological and behavioural responses in order to restore homeostasis. Water-saline homeostasis derives from balances of water and sodium intake and output (drinking and diuresis, salt appetite and natriuresis), maintaining an appropriate composition and volume of extracellular fluid. Thirst is the sensation which drives to seek and consume water, regulated in the central nervous system by both neural and chemical signals. Water and electrolyte homeostasis depends on finely tuned physiological mechanisms, mainly susceptible to plasma Na
+ concentration and osmotic pressure, but also to blood volume and arterial pressure. Increases of osmotic pressure as slight as 1-2% are enough to induce thirst ("homeostatic" or cellular), by activation of specialized osmoreceptors in the circumventricular organs, outside the blood-brain barrier. Presystemic anticipatory signals (by oropharyngeal or gastrointestinal receptors) inhibit thirst when fluids are ingested, or stimulate thirst associated with food intake. Hypovolemia, arterial hypotension, Angiotensin II stimulate thirst ("hypovolemic thirst", "extracellular dehydration"). Hypervolemia, hypertension, Atrial Natriuretic Peptide inhibit thirst. Circadian rhythms of thirst are also detectable, driven by suprachiasmatic nucleus in the hypothalamus. Such homeostasis and other fundamental physiological functions (cardiocircolatory, thermoregulation, food intake) are highly interdependent., (© 2023. The Author(s), under exclusive licence to Springer Nature B.V.)- Published
- 2023
- Full Text
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18. On Chronic Arsenical Poisoning from Wall Papers and Fabrics
- Author
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Sanger, Charles Robert
- Published
- 1893
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19. Appetite and its discontents: Science, medicine, and the urge to eat, 1750‐1950ElizabethWilliamsUniversity of Chicago Press, 2020. 426 pp. $35.00 (paper). ISBN 9780226693040; 9780226692999 (cloth); 9780226693187 (pdf)
- Author
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Alice Weinreb
- Subjects
History ,media_common.quotation_subject ,Appetite ,Psychology (miscellaneous) ,Art ,Religious studies ,media_common - Published
- 2021
20. Validation of a new hand-held electronic appetite rating system against the pen and paper method
- Author
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Mireille Moser, Hilary Green, Alfrun Erkner, Robert Virgili, Eva Almiron-Roig, and Jean-Marc Aeschlimann
- Subjects
Adult ,Male ,Paper ,medicine.medical_specialty ,Data variability ,Psychometrics ,Hunger ,Visual analogue scale ,media_common.quotation_subject ,Appetite ,Test validity ,Satiation ,Statistical variance ,Sensitivity and Specificity ,Developmental psychology ,Eating ,Surveys and Questionnaires ,medicine ,Humans ,Rating system ,General Psychology ,Pain Measurement ,media_common ,Nutrition and Dietetics ,digestive, oral, and skin physiology ,Hand held ,Reproducibility of Results ,Sensory Thresholds ,Physical therapy ,Female ,Electronics ,Psychology ,Thirst - Abstract
This study describes the validation of a new electronic appetite rating system, and a statistical variance model for visual analogue scale (VAS) research. Thirty volunteers rated hunger, fullness, desire to eat, prospective intake, thirst and liking on 100 mm paper VAS and on 70 mm electronic VAS presented on a Dell™ Pocket PC, after consuming breakfast, in a repeated trial. The electronic method was comparable in relative accuracy and reproducibility to the paper method, with weak differences between tests (within-subject SD ≤ 14 mm). The data obtained were used to generate a model for VAS data variability.
- Published
- 2009
21. Prefronto-cerebellar neuromodulation affects appetite in obesity.
- Author
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Marron EM, Viejo-Sobera R, Cuatrecasas G, Redolar-Ripoll D, Lorda PG, Datta A, Bikson M, Magerowski G, and Alonso-Alonso M
- Subjects
- Adult, Cross-Over Studies, Female, Humans, Male, Neurofeedback, Neuroimaging, Pilot Projects, Spain epidemiology, Treatment Outcome, Appetite physiology, Cerebellum, Feeding Behavior physiology, Obesity physiopathology, Obesity therapy, Prefrontal Cortex, Transcranial Direct Current Stimulation
- Abstract
Human neuroimaging studies have consistently reported changes in cerebellar function and integrity in association with obesity. To date, however, the nature of this link has not been studied directly. Emerging evidence suggests a role for the cerebellum in higher cognitive functions through reciprocal connections with the prefrontal cortex. The purpose of this exploratory study was to examine appetite changes associated with noninvasive prefronto-cerebellar neuromodulation in obesity. Totally, 12 subjects with class I obesity (mean body mass index 32.9 kg/m
2 ) underwent a randomized, single-blinded, sham-controlled, crossover study, during which they received transcranial direct current stimulation ((tDCS); active/sham) aimed at simultaneously enhancing the activity of the prefrontal cortex and decreasing the activity of the cerebellum. Changes in appetite (state and food-cue-triggered) and performance in a food-modified working memory task were evaluated. We found that active tDCS caused an increase in hunger and desire to eat following food-cue exposure. In line with these data, subjects also tended to make more errors during the working memory task. No changes in basic motor performance occurred. This study represents the first demonstration that prefronto-cerebellar neuromodulation can influence appetite in individuals with obesity. While preliminary, our findings support a potential role for prefronto-cerebellar pathways in the behavioral manifestations of obesity.- Published
- 2019
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22. Comparison of the traditional paper visual analogue scale questionnaire with an Apple Newton electronic appetite rating system (EARS) in free living subjects feeding ad libitum
- Author
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R. J. Stubbs, RJ Stratton, Neil A. King, John E. Blundell, Darren A. Hughes, and Marinos Elia
- Subjects
Adult ,Male ,Paper ,medicine.medical_specialty ,Hunger ,Visual analogue scale ,media_common.quotation_subject ,Appetite ,Medicine (miscellaneous) ,Audiology ,Sensitivity and Specificity ,Microcomputers ,Surveys and Questionnaires ,medicine ,Humans ,Rating system ,Reliability (statistics) ,media_common ,Cross-Over Studies ,Nutrition and Dietetics ,Data collection ,Significant difference ,Consumer Behavior ,Crossover study ,Preference ,Female ,Psychology - Abstract
Objective: Assessing the value of a newly developed electronic visual analogue scale questionnaire (Apple Newton Message Pad) with the traditional paper method for appetite rating. Design: In a random, crossover design, subjects completed both electronic and paper questionnaires to compare results obtained by the two methods; individual methods were completed consecutively to assess test-retest reliability; preference was established using a questionnaire. Setting/Subjects: Healthy, free-living adults were studied for comparison of methods (na 12), test-retest reliability (na 8) and preference (na 13). Intervention: Visual analogue scales were completed each waking hour to assess appetite. Preference was assessed after both methods were completed. Results: There was no significant difference in the hourly results obtained by the paper and electronic methods for ‘desire to eat’, ‘how much can you eat now’, ‘urge to eat’ and ‘preoccupation with thoughts of food’. Small differences in ‘hunger’ and ‘fullness’ ratings were noted ( 5% mean difference between methods, P< 0.05), but patterns of change and sensitivity for these and all other parameters remained similar for both methods across the visual analogue scale. Test-retest reliability demonstrated was similar for both methods. Seven (54%) subjects preferred to use the paper questionnaire, five (38%) the electronic method and one (8%) had no preference. Conclusions: The electronic Apple Newton questionnaire is as sensitive and reliable as the paper method, has the advantage that it automatically records the time of data acquisition and data collection and processing are more efficient for the researcher. The two methods should not be used interchangeably. Sponsorship: Medical Research Council. Descriptors: human; appetite; hunger; visual analogue scale
- Published
- 1998
23. Impact of Antiseizure Medications on Appetite and Weight in Children.
- Author
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Buraniqi E, Dabaja H, and Wirrell EC
- Subjects
- Anticonvulsants adverse effects, Child, Humans, Lamotrigine therapeutic use, Weight Gain, Appetite, Epilepsy drug therapy
- Abstract
There are numerous potential factors that may affect growth in children with epilepsy, and these must be evaluated in any child with appetite and weight concerns. Antiseizure medications (ASMs) have potential adverse effects, and many may affect appetite, thus impacting normal growth and weight gain. The aim of this review is to focus on the impact of both epilepsy and ASMs on appetite and weight in children. We systematically reviewed studies using Medline assessing the impact of ASMs on appetite and weight in children. Eligible studies included randomized controlled trials and open-label studies (open-label extension and interventional) that targeted or included the pediatric population (0-18 years of age). Each study was classified using the American Academy of Neurology (AAN) Classification of Evidence for Therapeutic Studies, and the level of evidence for impact on appetite and weight in children was graded. ASMs associated with decreased appetite and/or weight loss include fenfluramine, topiramate, zonisamide, felbamate, rufinamide, stiripentol, cannabidiol, brivaracetam and ethosuximide; ASMs with minimal impact on weight and appetite in children include oxcarbazepine, eslicarbazepine, lamotrigine, levetiracetam, lacosamide, carbamazepine, vigabatrin and clobazam. The ASM most robustly associated with increased appetite and/or weight gain is valproic acid; however, both pregabalin and perampanel may also lead to modest weight gain or increased appetite in children. Certain ASMs may impact both appetite and weight, which may lead to increased morbidity of the underlying disease and impaired adherence to the treatment regimen., (© 2022. The Author(s), under exclusive licence to Springer Nature Switzerland AG.)
- Published
- 2022
- Full Text
- View/download PDF
24. The effect of methyl donor supplementation on body composition, homocysteine, lipid profile and appetite regulatory hormones in overweight and obese adults: a randomized placebo-controlled trial
- Author
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Ranjbar Zahedani, Maryam, Eftekhari, Mohammad Hassan, Nouri, Mehran, Alipour, Shohreh, Hassanzadeh, Jafar, and Fardaei, Majid
- Published
- 2023
- Full Text
- View/download PDF
25. Effects of -methoxy derivatives of 3-trifluoromethylphenylethylamine on food intake and brain serotonin content.
- Author
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Cattabeni F, Revuelta A, and Costa E
- Subjects
- Animals, Brain Stem analysis, Carbon Isotopes, Chromatography, Gas, Chromatography, Paper, Diencephalon analysis, Fenfluramine metabolism, Half-Life, Kinetics, Male, Mass Spectrometry, Myocardium analysis, Norepinephrine analysis, Rats, Stomach analysis, Time Factors, Appetite drug effects, Brain Chemistry drug effects, Fenfluramine pharmacology, Serotonin analysis
- Published
- 1972
- Full Text
- View/download PDF
26. Agreement between paper and pen visual analogue scales and a wristwatch-based electronic appetite rating system (PRO-Diary), for continuous monitoring of free-living subjective appetite sensations in 7–10year old children
- Author
-
Caroline J. Dodd-Reynolds, Emma J. Stevenson, and Penny L. S. Rumbold
- Subjects
Male ,medicine.medical_specialty ,Hunger ,media_common.quotation_subject ,Sensation ,Food consumption ,Appetite ,Satiation ,Audiology ,Lower limit ,Eating ,Surveys and Questionnaires ,medicine ,Humans ,Limit (mathematics) ,Rating system ,Child ,General Psychology ,Monitoring, Physiologic ,media_common ,Communication ,Nutrition and Dietetics ,business.industry ,Continuous monitoring ,Female ,Electronics ,Psychology ,business - Abstract
Electronic capture of free-living subjective appetite data can provide a more reliable alternative to traditional pen and paper visual analogue scales (PP VAS), whilst reducing researcher workload. Consequently, the aim of this study was to explore the agreement between PP VAS and a wristwatch-based electronic appetite rating system known as the PRO-Diary© technique, for monitoring free-living appetite sensations in 7-10 year old children. On one occasion, using a within-subject design, the 12 children (n=6 boys; n=6 girls) recorded their subjective appetite (hunger, prospective food consumption, and fullness), at two time points before lunch (11:30 and 12:00) and every 60 min thereafter until 21:00. The agreement between the PP VAS and PRO-Diary© technique was explored using 95% limits of agreement and 95% confidence intervals (95% CI) calculated using the Bland and Altman (1986) technique. For hunger, prospective food consumption and fullness, the 95% limits of agreement were -1±25 mm (95% CI: lower limit -8mm; upper limit +6mm), 0±21 mm (95% CI: lower limit -6mm; upper limit +6mm) and -6±24 mm (95% CI: lower limit -14 mm; upper limit +1mm), respectively. Given the advantages associated with electronic data capture (inexpensive; integrated alarm; data easily downloaded), we conclude that the PRO-Diary© technique is an equivalent method to employ when continuously monitoring free-living appetite sensations in 7-10 year old children, but should not be used interchangeably with PP VAS.
- Published
- 2013
27. Validation of a Mobile App-Based Visual Analog Scale for Appetite Measurement in the Real World: A Randomized Digital Clinical Trial.
- Author
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Zhu, Yong, Blundell, John E., Holschuh, Norton M., McLean, Ross, and Menon, Ravi S.
- Abstract
There has been no validated digital tool for measuring appetite with a visual analog scale (VAS) through a mobile app using participants' smart phones for data collection in virtual settings. To fill the gap, we developed a digital VAS and conducted a digital cross-over clinical trial by comparing appetite responses measured by this digital tool versus paper-based VAS in 102 participants in a free-living environment. Participants consumed either a 230 or 460 kcal breakfast in randomized order in two virtual sessions, and their appetite was measured over the next 4 h using both tools. The results revealed no significant difference in hunger, fullness, satiety, or desire to eat measured by digital and paper VAS. Paper VAS resulted in a higher prospective consumption score than digital VAS; the difference (1.1 out of 100 points) was statistically significant but not practically relevant. Bland and Altman analysis also indicated consistency in the results from the two methods. In conclusion, digital VAS on a smart phone is a validated tool for appetite measurement in the real world; it provides a new way for researchers to leverage participants' mobile devices for appetite data collection in digital trials. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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28. Introduction to four papers on Curt Richter and analysis of his scientific practice
- Author
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Gerard P. Smith
- Subjects
Biomedical Research ,Nutrition and Dietetics ,Physiology ,Scientific practice ,Appetite ,Historical Article ,History, 19th Century ,Biography ,Claude bernard ,History, 20th Century ,Contemporary science ,Portrait ,Animals ,Nutritional Physiological Phenomena ,Psychology ,General Psychology ,Classics - Abstract
Curt Richter was one of the founders of our field. He did outstanding research for over 60 years. Richter did fundamental work in appetite for food and minerals in the 1930s and discovered the homeostatic functions of ingestive behavior. This paper introduces four papers on specific topics of his work by contemporaneous experts. Each of the papers reviews Richter's experiments and then shows how the problem developed since he left it. The papers demonstrate that providing the historical basis for contemporary science is not only instructive, it is also heuristic for the science waiting to be done. In addition to introducing the four papers, I analyze the scientific ideas, values, and men that influenced Richter's scientific practice. I conclude that Claude Bernard, Walter Cannon, Francois Magendie, and Maurice Arthus were important for Richter's scientific ideas and values, but it was the joy of research that explains his experimental success for over 60 years.
- Published
- 2007
29. Can plate colour promote appetite and joy while dining? An investigative study in Chinese fine dining restaurants
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Chen, Yen-Cheng, Tsui, Pei-ling, Lee, Ching-Sung, and Chen, Guan-lin
- Published
- 2020
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30. Associations of short sleep duration with appetite-regulating hormones and adipokines: A systematic review and meta-analysis.
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Lin J, Jiang Y, Wang G, Meng M, Zhu Q, Mei H, Liu S, and Jiang F
- Subjects
- Cross-Sectional Studies, Humans, Time Factors, Adipokines, Appetite, Sleep
- Abstract
In the current study, a systematic review and meta-analysis were conducted to summarize and assess whether short sleep duration is associated with appetite-regulating hormones and adipokine levels. Reference databases were searched for studies related to sleep and appetite-regulating hormones and adipokines. Qualitative and quantitative syntheses were conducted to evaluate the relationship between sleep duration and the level of appetite-regulating hormones and adipokines, including leptin, ghrelin, adiponectin, resistin, and orexin. Twenty-one of 3536 studies, covering a total of 2250 participants, met the inclusion criteria. Leptin, ghrelin, and adiponectin were included in the meta-analysis. Ghrelin levels were higher in the short sleep group (standard mean difference [SMD] = 0.14, 95% CI [0.03, 0.25], p = 0.01). Significant differences between the short sleep group and recommended sleep group were also noted in leptin level experimental subgroup studies (SMD = 0.19, 95% CI [0.03, 0.35], p = 0.02) and ghrelin level cross-sectional subgroup studies (SMD = 0.14, 95% CI [0.02, 0.27], p = 0.03). A rise in leptin and ghrelin levels were also observed in sleep deprivation groups (SMD = 0.24, 95% CI [0.10, 0.39], p = 0.001 and SMD = 0.18, 95% CI [0.04, 0.33], p = 0.01, respectively). In conclusion, short sleep duration is associated with an increased ghrelin level, while sleep deprivation had a significant effect on the levels of both leptin and ghrelin., (© 2020 World Obesity Federation.)
- Published
- 2020
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31. Warren J. Belasco. Appetite for Change: How the Counterculture Took On the Food Industry, 2nd ed. Ithaca, NY: Cornell University Press, 2007. xi + 327 pp. ISBN 978-0-8014-7329-6, $21.95 (paper)
- Author
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Jeffrey Charles
- Subjects
History ,Food industry ,business.industry ,Counterculture ,media_common.quotation_subject ,Political economy ,Political science ,Economic history ,Business, Management and Accounting (miscellaneous) ,Appetite ,business ,Agricultural economics ,media_common - Published
- 2009
32. Assessment of subjective appetite sensations in hemodialysis patients. Agreement and feasibility between traditional paper and pen and a novel electronic appetite rating system
- Author
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Neil A. King, Rachel Zabel, Susan Ash, and Judith Bauer
- Subjects
Adult ,Male ,medicine.medical_specialty ,Psychometrics ,Visual analogue scale ,Hunger ,medicine.medical_treatment ,media_common.quotation_subject ,Population ,Appetite ,Satiety Response ,Renal Dialysis ,medicine ,Humans ,Rating system ,education ,General Psychology ,Dialysis ,media_common ,Aged ,education.field_of_study ,Nutrition and Dietetics ,Reproducibility of Results ,Middle Aged ,Surgery ,Physical therapy ,Female ,Hemodialysis ,Psychology ,Psychopathology - Abstract
The aim of this study was to assess the agreement between a novel Electronic Appetite Rating System (EARS) and traditional paper and pen visual analog scales (VASs) in a clinical population. 28 hemodialysis patients (mean age 61 ± 17 years, 50% male, median dialysis vintage 19.5(4–101) months) were asked to rate their subjective sensations of hunger, fullness and desire to eat on VAS using both methods. The mean (S.D.) bias ranged from 2.6(16.6) mm to 6.2(15.7) mm which indicated that the two methods did not agree. Patients preferred the paper and pen method compared with the EARS. Either method would be suitable to use in a clinical population; however, it would be inappropriate to use the methods interchangeably.
- Published
- 2008
33. Is it the staff or is it the food? How the attire of restaurant employees affects customer judgments of food quality
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Chen, Yen-Cheng Daniel and Lee, Ching-Sung
- Published
- 2018
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34. APPetite: validation of a smartphone app-based tool for the remote measure of free-living subjective appetite.
- Author
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Holliday, Adrian, Johnson, Kelsie Olivia, Kaiseler, Mariana, and Crabtree, Daniel R.
- Subjects
APPETITE ,FOOD habits ,RESEARCH evaluation ,MOBILE apps ,RESEARCH methodology evaluation ,RESEARCH methodology ,SMARTPHONES ,VISUAL analog scale ,HUNGER ,QUALITATIVE research - Abstract
This study determined the validity, reproducibility and usability of a smartphone app – APPetite – for the measure of free-living, subjective appetite. Validity was assessed compared with the criterion tool of pen-and-paper visual analogue scale (VAS) (n 22). Appetite was recorded using APPetite and VAS, one immediately after the other, upon waking and every hour thereafter for 12 h. This was repeated the next day with the order of tool reversed. Agreement between tools was assessed using Bland–Altman analysis. Reproducibility and usability were assessed in a separate experiment (n 22) of two trials (APPetite v. VAS), separated by 7 d. Appetite was recorded in duplicate upon waking and every hour for 12 h using APPetite or VAS. Agreement between duplicate measures was assessed using Bland–Altman analysis and CV was compared between tools. Usability was assessed by comparing compliance and by qualitative evaluation. APPetite demonstrated good criterion validity with trivial bias of 1·65 units/mm·h
–1 between APPetite- and VAS-derived AUC appetite scores. Limits of agreement were within a maximum allowed difference of 10 %. However, proportional bias was observed. APPetite demonstrated high reproducibility, with minimal bias (–0·578 units·h–1 ) and no difference in CV between APPetite and VAS (1·29 ± 1·42 % v. 1·54 ± 2·36 %, P = 0·64). Compliance was high with APPetite (92·7 ± 8·0 %) and VAS (91·6 ± 20·4 %, P = 0·81). Ninety percent of participants preferred APPetite, citing greater accessibility, simplified process and easier/quicker use. While proportional bias precludes using APPetite and VAS interchangeably, APPetite appears a valid, reproducible and highly usable tool for measuring free-living appetite in young-to-middle-aged adults. [ABSTRACT FROM AUTHOR]- Published
- 2023
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35. Introduction to papers presented at: the twenty fifth anniversary symposium of the Columbia University Seminar on Appetitive Behavior
- Author
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Harry R. Kissileff
- Subjects
Nutrition and Dietetics ,Feeding behavior ,Columbia university ,Library science ,Appetite ,Humans ,Feeding Behavior ,Psychology ,General Psychology - Published
- 1997
36. EFFECT OF AFRICAN BASIL (Ocimum gratissimum) ON OREXIGENIC FACTORS AND ZOOTECHNICAL PERFORMANCE OF AFRICAN CATFISH (Clarias gariepinus)
- Author
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Oluyemi Gbadamosi, Ojo P. Oke, and T. S Olayeni
- Subjects
aquafeed ,EFFECT OF AFRICAN BASIL (Ocimum gratissimum) ON OREXIGENIC FACTORS AND ZOOTECHNICAL PERFORMANCE OF AFRICAN CATFISH (Clarias gariepinus), Oluyemi Gbadamosi, Ojo P. Oke, T. S Olayeni, ISSN 2349-7823, International Journal of Recent Research in Life Sciences (IJRRLS), Paper Publications, DOI: https://doi.org/10.5281/zenodo.6861555 ,growth ,physiology ,Appetite ,digestion ,fish farming - Abstract
Appetite and food intake in fish is not only affected by external factors but also endogenous factors such as the hypothalamus which is the hub controlling appetite, energy balance and integration of peripheral signals related to appetite, feed intake, digestion and metabolism. African basil, Ocimmum gratissimum leaf is proven to improve food palatability and stimulate appetite through its characteristic aroma. In this study, the effects of African basil Ocimmum gratissimum leafmeal on orexigenic factors and zootechnical performance in African catfish Clarias gariepinus diet was assessed for a period of 56 days. Six isonitrogenous diets were formulated at different inclusion levels of Ocimmum gratissimum leaves at 0 mg/g, 10 mg/g, 20 mg/g, 30mg/g, 40 mg/g, 50 mg/g denoted as T1, T2, T3, T4, T5 and T6 respectively. C. gariepinus fingerlings (2.57±0.37g) were randomly divided into the replicates of six treatments group. The test fish were randomly distributed into 18 plastic tanks with the dimension of 40×30×35 (cm)³ at the stocking density of 10 fish per tank. After the feeding trials, histology of orexigenic factors, growth performance and nutrient utilisation parameters were assessed. C. gariepinus fingerlings fed 30mg/g diet of O. gratissimum recorded the best growth performance in terms of feed intake, body weight gain, feed conversion ratio (FCR) and specific growth rate (SGR). There was a significant increase (pC. gariepinus fingerlings with increasing inclusion of O. gratissimum leaves (PC. gariepinus. This study therefore confirmed the endogenous and physiological benefits of O. gratissimum on the the appetite and zootechnical performance of C. gariepinus. Keywords: Appetite, aquafeed, digestion, fish farming, growth, physiology. Title: EFFECT OF AFRICAN BASIL (Ocimum gratissimum) ON OREXIGENIC FACTORS AND ZOOTECHNICAL PERFORMANCE OF AFRICAN CATFISH (Clarias gariepinus) Author: Oluyemi Gbadamosi, Ojo P. Oke, T. S Olayeni International Journal of Recent Research in Life Sciences (IJRRLS) ISSN 2349-7823 Vol. 9, Issue 3, July 2022 - September 2022 Page No: 1-8 Paper Publications Website: www.paperpublications.org Published Date: 19-July-2022 DOI: https://doi.org/10.5281/zenodo.6861555 Paper Download Link (Source) https://www.paperpublications.org/upload/book/EFFECT%20OF%20AFRICAN%20BASIL-19072022-9.pdf, International Journal of Recent Research in Life Sciences (IJRRLS), ISSN 2349-7823, Paper Publications, Website: www.paperpublications.org, {"references":["[1]\tAbdelhamid AM, Radwan IA, Mehrim AI (2010) Improving the survival rate of African catfish Clarias gariepinus. Jornal of Animal and Poultry Production, 1(9), 409-414.","[2]\tAbdel – Razek N, Awad SM, Abdel – Tawwab M (2019) Effect of dietary purslane (Portulaca oleracea L.) leaves powder on growth, immunostimulation and protection of Nile tilapia, Oreochromis niloticus against Aeromonas hydrophila infection. Fish physiology and biochemistry, 45(6), 1907 – 1917","[3]\tAbdel – Tawwab M, Adeshina I., Jenyo-Oni, A., Ajani, EK, Emikpe BO (2018) Growth, physiological, antioxidants and immune response of African catfish Clarias gariepinus to dietary clove basil, Osimum gratissimum, leaf extract and its susceptibility to Listeria monocytogens infection. Fish shellfish immunology 78, 346-354","[4]\tAfe OE, Dada AA, Olufayo MO (2019) Effects of varying levels of Ocimum gratissimum leaf powder on growth performance and feed utilization of Heterobranchus bidorsalis fingerlings. African Jornals of Fisheries and Aquatic Resources Management, 4, 35-42","[5]\tAyotunde EO, Fagbenro OA, Adebayo OT (2011) Toxicity of aqueous extract of Moring oleifera seed powder to Nile tilapia Oreochromis niloticus (LINNEUS 1779), fingerlings. International Research Jornal of Agricultural Science and Soil Science, 1(4), 142-150","[6]\tDada AA, Abiodun AD, (2014) Effect dietary fluted pumpkin (Telfairia occidentallis) extract on growth performance, body composition and haematological parameters of Nile tilapia Oreochromis niloticus. Jornal of Fisheries, 2(3), 203-208","[7]\tDiana JS (2009) Aquaculture Production and Biodiversity Conservation. Bioscience, 59(1), 27-38","[8]\tFujimoto RY, Pereira DM, Silva JCS, Oliveira LCA, Inouve LAKA, Hamoy M, Barbas LAL (2018) Clove oil induces anaesthesia and blunt muscle contraction power in three amazon fish species. Fish physiology and biochemistry, 44(1), 245-256","[9]\tGbadamosi OK, Salako F (2014) Gustation and growth performance of African catfish, Clarias gariepinus fed varying levels of dietary African basil, Ocimum gratissimum leaf supplementation. Egyptian academic jornal of biological science. 6(1): 9-15","[10]\tHagi T, Hoshino T (2009) Screening and characterization of potential probiotic lactic acid bacteria from cultured common carp intestine. Bioscience, biotechnology and biochemistry, 73(7), 1479-1483.","[11]\tJiang J, Qi L, Lv Z, Wei Q, Shi F (20210 Dietary stevioside supplementation increases feed intake by altering the hypothalamic transcriptome profile and gut microbiota in broiler chickens. Jornal of the science of food and agriculture, 10(15), 2156-2167","[12]\tKorte SM, Olivier B, Koolhaas JM (2007) A new animal welfare concept based on allostasis. Physiology and behaviour, 92(3), 422-428","[13]\tMcEwen BS, Wingfield JC (2003) The concept of allostasis in biology and biomedicine. Hormone and behaviour, 43(1), 2-15","[14]\tMommsen TP (2002) Paradigms of growth in fish. Comparative biochemistry and physiology part B: biochemistry and molecular biology, 129(2-3), 207-219","[15]\tRonnestad I, Gomes AS, Murashita K, Angotzi R, Jonsson E, Volkoff H (2017) Appetite-controlling endocrine systems in teleosts. Frontiers in endocrinology, 8, 73.","[16]\tSaleh R, Bentancor MB, Roo J, Benitez-Dorta V, Zamorano MJ, Bell JG, Izquierdo M (2015) Effect of krill phospholipids versus soybean lecithin in microdiets for gilthead seabream 9S patrus aurata) larvae on molecular markers of antioxidative metabolism and bone development. Aquaculture Nutrition, 21(4), 474-488.","[17]\tSoltan M, El-L S (2008) Effect of probiotics and some species as feed additives on the performance and behaviour of the Nile tilapia, Oreochromis niloticus. Egyptian Jornal of Aquatic Biology and Fisheries, 12(2), 63-80","[18]\tTacon AG, Metian MM, Turchini GM, De Silva SS (2009) Responsible aquaculture and tropic level implication to global fish supply. Reviews in fisheries science, 18(1), 94-105","[19]\tViveen, W. A. R., Richter, C. J. J., Van Oordt, P. G. W. J., Janssen, J. A. L., Huisman, E. A. (1985). Practical Manual for the Culture of the African Catfish (Clarias gariepinus)"]}
- Published
- 2022
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- View/download PDF
37. A Widow's Diet: Negotiating Politics of Food and Widowhood in The Anger of Aubergines.
- Author
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Samal, Rajbir and Mishra, Binod
- Subjects
WIDOWHOOD ,POLITICAL science - Abstract
Widowhood, in Indian society, is a dreaded condition of a woman after the death of her husband. It is an imposed performance that entails a set of ritualized practices and behavior to mark her transition to the state of a woman without. On many occasions, this state is ensured and maintained through multifarious rituals and practices, which range from restrictions on mobility, choices, and desires to injunctions on clothes, bodily demeanor, and food. This physio-social exercise of control and restraint alludes to a framework of religio-cultural discourse that renders widows as social and sexual non-beings. The present paper attempts to understand the state of widowhood through the analysis of two short stories in the collection, The Anger of Aubergines (1997) by Bulbul Sharma from the perspective of food. Food and eating, being the elementary aspects of everyday life, become important signifiers in studying the deprived state of widowhood. The paper intends to unpack the politics behind the imposition of a curriculum of gastronomic injunctions and food taboos on Hindu upper-caste widows. Further, the paper conceptualizes the appetite of widows as a subversive category not only in challenging the gender discourses behind their oppression but also in exonerating their status as desireless beings. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
38. Randomised controlled trials of antipsychotics for people with autism spectrum disorder: a systematic review and a meta-analysis.
- Author
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Deb, Shoumitro, Roy, Meera, Limbu, Bharati, Akrout Brizard, Basma, Murugan, Meena, Roy, Ashok, and Santambrogio, Jacopo
- Subjects
APPETITE ,MEDICAL databases ,PSYCHOLOGY information storage & retrieval systems ,CINAHL database ,META-analysis ,CONFIDENCE intervals ,ANESTHESIA ,MEDICAL information storage & retrieval systems ,SYSTEMATIC reviews ,RISK assessment ,WEIGHT gain ,AUTISM ,DESCRIPTIVE statistics ,DRUG side effects ,MEDLINE ,ANTIPSYCHOTIC agents ,ERIC (Information retrieval system) - Abstract
Background: Despite unclear evidence to support the long-term use of antipsychotics to treat challenging (problem) behaviours in people with autism in the absence of a psychiatric disorder, this practice is common. Methods: We conducted a systematic review and meta-analysis of all randomised controlled trials (RCTs) involving antipsychotics for people with autism of all ages, irrespective of the outcomes assessed. We searched seven databases and hand-searched ten relevant journals. Two authors independently screened titles, abstracts and full papers and extracted data using the Cochrane Handbook template. We conducted meta-analyses of outcomes and the rate of adverse events. Results: We included 39 papers based on 21 primary RCTs that recruited 1482 people with autism. No RCT assessed any psychiatric disorder outcome, such as psychoses or bipolar disorder. A meta-analysis of ten placebo-controlled RCTs showed a significantly improved Aberrant Behaviour Checklist-Irritability score in the antipsychotic group with an effect size of −6.45 [95% confidence interval (CI) −8.13 to −4.77] (low certainty). Pooled Clinical Global Impression data on 11 placebo-controlled RCTs showed an overall effect size of 0.84 (95% CI 0.48 to 1.21) (moderate certainty). There was a significantly higher risk of overall adverse effects (p = 0.003) and also weight gain (p < 0.00001), sedation (p < 0.00001) and increased appetite (p = 0.001) in the antipsychotic group. Conclusions: There is some evidence for risperidone and preliminary evidence for aripiprazole to significantly improve scores on some outcome measures among children with autism but not adults or for any other antipsychotics. There is a definite increased risk of antipsychotic-related different adverse effects. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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- View/download PDF
39. Individual variability and consistency of post-exercise energy and macronutrient intake, appetite sensations, and food reward in healthy adults.
- Author
-
Pélissier L, Lambert C, Stensel DJ, Beraud D, Finlayson G, Pereira B, Boirie Y, Duclos M, Isacco L, and Thivel D
- Subjects
- Humans, Female, Male, Adult, Young Adult, Satiation physiology, Nutrients, Surveys and Questionnaires, Appetite physiology, Exercise physiology, Exercise psychology, Reward, Energy Intake physiology, Food Preferences psychology, Food Preferences physiology
- Abstract
Limited evidence is available about the variability of appetitive responses within individuals after an acute bout of exercise. The present study aimed to assess the consistency and individual variability of post-exercise appetitive responses in healthy individuals. Twenty participants (10 females, 23.9 ± 4.1 years, 22.5 ± 2.0 kg m
-2 ) joined the laboratory to perform four sessions separated by a minimum of 5 days: i) a control session with a rest period before and an ad libitum lunch (REST), and ii) three identical exercise sessions (EX) with a 30-min moderate-intensity (60-70% of predicted maximal heart rate) walking bout ending 25 min before the ad libitum lunch. Subjective appetite sensations were assessed before and after the meal at regular intervals, and satiety quotients were calculated. Food reward was assessed by the Leeds Food Preference Questionnaire before and after lunch. For each EX session, the difference with the REST session was calculated (Δ = EX - REST). Energy and macronutrient intake were consistent in response to exercise (all intraclass correlation coefficients (ICC) > 0.8) while results showed that post-exercise subjective appetite sensations and satiety quotients varied across the three EX sessions (almost all ICC < 0.7). Food reward was overall consistent in response to exercise before the test meal but not after. When considering the changes (Δ), the results showed no or poor consistency for most of the appetitive outcomes. To conclude, energy and macronutrient intake, as well as pre-meal food reward, are consistent after exercise in healthy individuals, while subjective appetite sensations are not stable within individuals across the sessions. Regarding the variations from REST to EX sessions, the results suggest that the individual changes observed are only random day-to-day variations., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)- Published
- 2024
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- View/download PDF
40. Dietary polyphenols regulate appetite mechanism via gut-brain axis and gut homeostasis.
- Author
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Liu H, Guo X, Jiang K, Shi B, Liu L, Hou R, Chen G, Farag MA, Yan N, and Liu L
- Subjects
- Brain-Gut Axis, Polyphenols metabolism, Homeostasis, Appetite, Gastrointestinal Microbiome physiology
- Abstract
Nowadays, due to the rise of fast-food consumption, the metabolic diseases are increasing as a result of high-sugar and high-fat diets. Therefore, there is an urgent need for natural, healthy and side-effect-free diets in daily life. Whole grain supplementation can enhance satiety and regulate energy metabolism, effects that have been attributed to polyphenol content. Dietary polyphenols interact with gut microbiota to produce intermediate metabolites that can regulate appetite while also enhancing prebiotic effects. This review considers how interactions between gut metabolites and dietary polyphenols might regulate appetite by acting on the gut-brain axis. In addition, further advances in the study of dietary polyphenols and gut microbial metabolites on energy metabolism and gut homeostasis are summarized. This review contributes to a better understanding of how dietary polyphenols regulate appetite via the gut-brain axis, thereby providing nutritional references for citizens' dietary preferences., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier Ltd. All rights reserved.)
- Published
- 2024
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- View/download PDF
41. A study on the effects of metacinnabar (β-HgS) on weight and appetite recovery in stressed mice.
- Author
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Qiao Y, Chen H, Guo J, Zhang X, Liang X, Wei L, Wang Q, Bi H, and Gao T
- Subjects
- Animals, Male, Mice, Body Weight drug effects, Depression drug therapy, Antidepressive Agents pharmacology, Disease Models, Animal, Hippocampus drug effects, Hippocampus metabolism, Behavior, Animal drug effects, Stress, Psychological drug therapy, Appetite drug effects, Gastrointestinal Microbiome drug effects
- Abstract
Ethnopharmacological Relevance: Depression is a prevalent stress disorder, yet the underlying physiological mechanisms linking stress to appetite and weight loss remain elusive. While most antidepressants are associated with excessive weight and appetite gain, sertraline (SER) exhibits a lower risk of these side effects. Metacinnabar (β-HgS), the primary component of Tibetan medicine Zuotai, has been shown to enhance mice's resilience against external stress without causing excessive increases in weight or appetite. However, the precise physiological pathway through which β-HgS restores appetite and weight in stressed mice remains unclear., Aim of the Study: The objective of this study is to assess the efficacy of β-HgS in ameliorating weight loss and appetite suppression induced by pressure stimulation in mice, as well as elucidate its potential mechanisms of action., Methods: The present study employed chronic restraint stress (CRS) and chronic unpredictable mild stress (CUMS) as experimental models to simulate environmental stress encountered in daily life. Subsequently, a series of experiments were conducted, including behavior tests, HE staining of rectal and hippocampal pathological sections, detection of depression-related biological indicators, analysis of intestinal flora diversity, as well as metabolomics analysis of hippocampal and intestinal contents., Result: Dysregulation of glycerophospholipid metabolism may represent the principal pathway underlying reduced appetite, body weight, neurotransmitter and appetite hormone levels, heightened inflammatory response, hippocampal and rectal tissue damage, as well as altered composition of intestinal microbiota in stressed mice. Following intervention with SER and β-HgS in stressed mice, the deleterious effects induced by stress can be ameliorated, in which the medium-dose β-HgS exhibited superior performance., Conclusion: The aforementioned research findings suggest that the stress-induced decrease in appetite and body weight in mice may be associated with dysregulation in glycerophospholipid metabolism connecting the gut-brain axis. β-HgS exhibits potential in ameliorating depressive-like symptoms in mice subjected to stress, while concurrently restoring their body weight and appetite without inducing excessive augmentation. Its therapeutic effect may also be attributed to its ability to modulate glycerophospholipid metabolism status and exert influence on the gut-brain axis., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2024 Elsevier B.V. All rights reserved.)
- Published
- 2024
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- View/download PDF
42. Exploring palliative care practice and learning needs of allied health professionals in the Loddon Mallee region of Victoria: a cross-sectional survey.
- Author
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Rodda, Lucy and Barrett, Stephen
- Subjects
CROSS-sectional method ,SELF-evaluation ,HEALTH services accessibility ,PALLIATIVE treatment ,MEDICAL quality control ,CONFIDENCE ,APPETITE ,DESCRIPTIVE statistics ,ALLIED health personnel ,RURAL health services ,SURVEYS ,ATTITUDES of medical personnel ,PROFESSIONAL employee training ,MEDICAL needs assessment ,TERMINAL care ,PUBLIC health ,TERMINALLY ill - Abstract
Objectives: The objectives of this study were to examine the roles and needs of allied health professionals (AHPs) working in public healthcare settings in rural and regional Victoria, Australia in providing components of palliative care in their routine practice. Methods: A cross-sectional study was conducted between March and May 2023. Surveys were collected from AHPs working in public healthcare settings in the Loddon Mallee region of Victoria, Australia. Clinicians reported on the frequency of provision of care to patients with terminal illness, and their self-reported skill and confidence in providing interventions to patients with palliative care needs. Results: In total, 121 clinicians completed the survey. Almost every respondent reported they had provided care to patients with a terminal illness, with 41% of clinicians providing this care daily or weekly. The respondents were confident carrying out generalist interventions such as maintaining physical function but reported lower confidence in managing common symptoms of terminal illness such as loss of appetite, swallowing difficulties and changing communication needs. Two-thirds of respondents had not undertaken any training specific to palliative care, with many unaware of how to access palliative care-specific training. Conclusion: AHPs in rural and remote areas regularly provide care to patients with terminal illness. As the number of patients seen in non-specialist palliative care settings is likely to increase in rural and regional areas, the low self-reported confidence in providing common components of care, and the low uptake of palliative care-specific training must be addressed to ensure AHPs can provide high-quality care to people with terminal illness. What is known about the topic? Due to the increasing demand for palliative care services, this care is increasingly delivered by general non-specialist clinicians such as allied health professionals. What does this paper add? This study provides evidence for how often a surveyed population of allied health professionals in rural and regional Australia are providing care to people with a terminal illness, as well as their confidence, competence and learning needs. What are the implications for practitioners? High-quality care is needed at end-of-life, therefore rural and regional health services need to support allied health professionals to increase confidence and competence in providing palliative care. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
43. Effect of a novel rice fermented extract on gastric ulcers in horses
- Author
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Yasuho Taura, Yumi Fujiwara, Shigeto Ushiya, Yasunobu Nishi, Takaaki Tokuyama, Tetsuya Takeyama, Samantha Senarathna, Yoshitaka Nishihara, Takahito Tokuyama, Tomohiro Mii, Hayata Kumagai, Satomi Ayaki, Naoki Sasaki, Kosuke Matsuno, Yuki Nakagawa, and Takashi Tokuyama
- Subjects
medicine.medical_specialty ,—Full Paper— ,gastric ulcer ,Equine ,business.industry ,media_common.quotation_subject ,Mucosal lesions ,food and beverages ,Horse ,Appetite ,rice fermented extract ,Gastroenterology ,digestive system diseases ,Poor body condition ,horse ,medicine.anatomical_structure ,Internal medicine ,Gastric mucosa ,Medicine ,Fermentation ,business ,media_common - Abstract
Gastric ulcers cause appetite loss, poor body condition, and colic in horses. This study investigated the protective effect of a rice fermented extract on the gastric mucosa in 17 healthy Thoroughbreds. For one month, horses in the rice fermented extract (nine horses) and control (eight horses) groups were orally administered a rice fermented extract (100%; 0.2 ml/kg, SID) and tap water (0.2 ml/kg), respectively. Gastric endoscopic images were obtained before and one month after rice fermented extract administration. The gastric ulcer score was lower after administration (median, 1; maximum, 2; minimum, 1) than before administration (median, 4; maximum, 4; minimum, 3) in the rice fermented extract group (P
- Published
- 2021
44. Ghrelin and oral diseases
- Author
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Sylwia Małgorzata Słotwińska
- Subjects
Saliva ,medicine.medical_specialty ,media_common.quotation_subject ,Immunology ,Stimulation ,stomatognathic system ,Internal medicine ,healing ,Immunology and Allergy ,Medicine ,Glucose homeostasis ,oral diseases ,Receptor ,media_common ,Review Paper ,business.industry ,digestive, oral, and skin physiology ,salivary secretion ,Appetite ,oral cancer ,Endocrinology ,ghrelin ,Cancer cell ,Ghrelin ,business ,hormones, hormone substitutes, and hormone antagonists ,Hormone - Abstract
Eating food is one of the most complicated behaviours in mammals, especially humans. The primary function of ghrelin is regulation of the appetite level and its stimulation. It is also responsible for the body's energy balance and glucose homeostasis. Ghrelin has been shown to affect many brain structures, which confirms the presence of ghrelin receptors in the brain. Studies are also conducted to assess the possible role of ghrelin in anxiety states and in memory disorders and motor dysfunctions. Ghrelin has been found in saliva and salivary glands, teeth and gums, and in the taste buds of the tongue epithelium; it is also secreted by mucosal cells and gingival fibroblasts. The presence of ghrelin in developmental enamel, especially in odontoblasts and ameloblasts, may suggest its regulatory role in the development of teeth. Patients with chronic periodontitis have significantly higher concentrations of ghrelin in the peripheral blood serum, as compared to the control group. Ghrelin plays a special role in the proliferation of cancer cells and in the development of neoplastic metastases. The abundant presence of ghrelin receptors in cancer cells is considered an important target in the treatment of neoplasms. Ghrelin is a hormone whose multidirectional mechanism of action has not yet been fully understood. However, its ubiquitous occurrence in the human body and its very diverse participation in metabolic processes may prove to be a significant obstacle in achieving the expected clinical effect of ghrelin as an effective drug in selected disease units.
- Published
- 2021
45. Gut Microbiota–Brain Axis in Regulation of Feeding Behavior.
- Author
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Fetissov, Sergueï O.
- Subjects
METABOLIC disorders ,FOOD consumption ,THERAPEUTICS ,ANOREXIA nervosa ,GUT microbiome - Abstract
The survival of microorganisms inhabiting the intestinal tract depends on the nutrients provided by the host, with the latter obtaining them through food intake. It is hence not surprising that the co-evolution of gut bacteria and their hosts, including humans, shaped intrinsic interactions between their respective metabolisms with an impact on host feeding behavior. Understanding molecular pathways underlying such interactions may aid in the development of new therapeutic approaches for several pathological conditions accompanied by altered feeding behavior. A Special Issue titled "Gut Microbiota–Brain Axis in Regulation of Feeding Behavior" contributes to this topic of research, with eight papers covering its various aspects such as autoprobiotics, metabolic diseases and anorexia. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
46. Poor appetite and overeating reported by adults in Australia during the coronavirus-19 disease pandemic: a population-based study
- Author
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Maggie Kirkman, Thach Duc Tran, Jane Fisher, Alice J. Owen, and Karin Hammarberg
- Subjects
Adult ,Male ,0301 basic medicine ,medicine.medical_specialty ,Adolescent ,media_common.quotation_subject ,Appetite ,Medicine (miscellaneous) ,Disease ,Anxiety ,Hyperphagia ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Surveys and Questionnaires ,Prevalence ,Humans ,Medicine ,030212 general & internal medicine ,Overeating ,Psychiatry ,Pandemics ,Depression (differential diagnoses) ,Aged ,media_common ,030109 nutrition & dietetics ,Nutrition and Dietetics ,Pandemic ,Depression ,SARS-CoV-2 ,business.industry ,Australia ,Public Health, Environmental and Occupational Health ,COVID-19 ,Middle Aged ,Patient Health Questionnaire ,Logistic Models ,Poor Appetite ,Socioeconomic Factors ,Cohort ,Female ,medicine.symptom ,business ,Research Paper - Abstract
Objective:As a result of the coronavirus-19 disease (COVID-19) pandemic, Australia adopted emergency measures on 22 March 2020. This study reports the effect of the COVID-19 lockdown on appetite and overeating in Australian adults during the first month of emergency measures.Design:This study reports analysis of data from the population-based, self-completed survey. The main outcome measure was an item from the Patient Health Questionnaire 9 asking: ‘Over the past 2 weeks, how often have you been bothered by poor appetite or overeating?’. Data on sociodemographic factors, symptoms of anxiety and depression, and the impact of COVID-19 and lockdown were also collected. Multivariable logistic regression was used to examine associations with poor appetite or overeating.Setting:An anonymous online survey available from 3 April to 2 May 2020.Participants:A total of 13 829 Australian residents aged 18 years or over.Results:The weighted prevalence of being bothered by poor appetite or overeating in the past 2 weeks was 53·6 %, with 11·6 % (95 % CI 10·6, 12·6) of the cohort reporting poor appetite or overeating nearly every day. High levels of anxiety, concern about contracting COVID-19, being in lockdown with children and reporting a severe impact of the lockdown were associated with increased odds of poor appetite or overeating.Conclusions:Given the widespread prevalence of being bothered by poor appetite or overeating, universal public health interventions to address emotion-focused or situational eating during periods of lockdown may be appropriate.
- Published
- 2020
47. The impact of acute changes of inflammation on appetite and food intake among older hospitalised patients
- Author
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Timm H. Westhoff, Gregor Janssen, Rainer Wirth, Maryam Pourhassan, Nina Babel, and Lars Sieske
- Subjects
Male ,medicine.medical_specialty ,Cachexia ,media_common.quotation_subject ,Appetite ,Medicine (miscellaneous) ,law.invention ,Eating ,Food intake ,Risk Factors ,Interquartile range ,law ,Surveys and Questionnaires ,Internal medicine ,medicine ,Humans ,Longitudinal Studies ,Geriatric Assessment ,Aged ,media_common ,Inflammation ,Aged, 80 and over ,Nutrition and Dietetics ,biology ,business.industry ,Malnutrition ,C-reactive protein ,Full Papers ,medicine.disease ,Intensive care unit ,Hospitalization ,C-Reactive Protein ,Nutrition Assessment ,Poor Appetite ,Older subjects ,biology.protein ,Female ,Observational study ,business ,Human and Clinical Nutrition - Abstract
The present study aimed to investigate the effect of acute changes in serum C-reactive protein (CRP) on appetite and food intake among older hospitalised patients. A total of 200 patients (age range 65–94 years, 62·5 % women) participated in this prospective longitudinal observational study. Risk of malnutrition was measured according to the Mini Nutritional Assessment Short Form. The Simplified Nutritional Appetite Questionnaire (SNAQ) and Edmonton Symptom Assessment System (ESAS) were used to evaluate patients’ appetite at the time of hospital admission (baseline) and after 7 d (follow-up). Food intake was measured according to the plate diagram and serum CRP was analysed at baseline and follow-up. At baseline, 30·5 % of the patients had moderate to severe inflammation, 31·0 % were malnourished and 48·0 % had food intake P = 0·006) in patients with a decrease in CRP level and deteriorated in those with an increase in CRP level (P = 0·032). Changes in CRP levels did not show any significant impact on food intake. In a regression analysis, changes of inflammation were the major independent predictor for changes of patients’ appetite. We conclude that inflammation has a significant impact on appetite and should therefore be considered in the diagnosis and treatment of malnutrition.
- Published
- 2020
48. Salt need needs investigation
- Author
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Micah Leshem
- Subjects
Adult ,Male ,Attractiveness ,Salt appetite ,Appetite ,Medicine (miscellaneous) ,030204 cardiovascular system & hematology ,Eating ,03 medical and health sciences ,0302 clinical medicine ,Extant taxon ,Environmental health ,Salt intake determinants ,Humans ,Medicine ,030212 general & internal medicine ,Salt intake ,Aged ,Aged, 80 and over ,Nutrition and Dietetics ,business.industry ,Behaviour, Appetite and Obesity ,Nutritional Requirements ,Sodium, Dietary ,Middle Aged ,Full Papers ,Diet ,Flavoring Agents ,Mood ,Female ,Causes of salt intake ,business ,Salt intake research - Abstract
Expensive and extensive studies on the epidemiology of excessive Na intake and its pathology have been conducted over four decades. The resultant consensus that dietary Na is toxic, as well as the contention that it is less so, ignores the root cause of the attractiveness of salted food. The extant hypotheses are that most Na is infiltrated into our bodies via heavily salted industrialised food without our knowledge and that mere exposure early in life determines lifelong intake. However, these hypotheses are poorly evidenced and are meagre explanations for the comparable salt intake of people worldwide despite their markedly different diets. The love of salt begins at birth for some, vacillates in infancy, climaxes during adolescent growth, settles into separate patterns for men and women in adulthood and, with age, fades for some and persists for others. Salt adds flavour to food. It sustains and protects humans in exertion, may modulate their mood and contributes to their ailments. It may have as yet unknown benefits that may promote its delectability, and it generates controversy. An understanding of the predilection for salt should allow a more evidence-based and effective reduction of the health risks associated with Na surfeit and deficiency. The purpose of this brief review is to show the need for research into the determinants of salt intake by summarising the little we know.
- Published
- 2020
49. Appetite and family and friends network among community-dwelling older adults: A cross-sectional study.
- Author
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Noritake K, Fujii K, Kubo Y, Yorozuya K, Hayashi T, Goto F, Watanabe H, Yoshida A, Tsubouchi Y, and Nakashima D
- Subjects
- Humans, Female, Aged, Aged, 80 and over, Cross-Sectional Studies, Independent Living, Friends, Appetite physiology, Malnutrition
- Abstract
Objectives: The aim of this study was to investigate the stronger correlate of appetite-family or friend networks-in community-dwelling older adults, given that undernutrition can impair physical function, increase mortality, and be influenced by social networks., Methods: A cross-sectional study was conducted in Kasugai City, Aichi Prefecture, and Nara City, Nara Prefecture, Japan, between August 2019 and March 2023. The analysis included 119 participants (women: 79%, mean age: 76.5 ± 5.6 y). A multiple regression analysis was performed, using the scores from the Japanese version of the Simplified Nutritional Appetite Questionnaire (SNAQ-J) as the dependent variable and family network and friend network as the independent variables. The analysis included social participation, living alone status, sex, age, body mass index, skeletal muscle mass index, grip strength, walking speed, and the Japanese version of the 15 Geriatric Depression Scale score as covariates to examine their relationship with appetite., Results: The mean value of the SNAQ-J score of the participants was 15.4 ± 1.2. Seven participants (6%) had a loss of appetite. Family network was significantly associated with appetite (B = 0.121, β = 0.266, P <0.05; 95% condidence interval [CI], 0.030-0.212). In the single regression analysis, the friend network was significantly associated with the total score of the SNAQ-J (B = 0.115, P <0.001; 95% CI, 0.052-0.177); however, this association was not observed in the multiple regression analysis (B = 0.002, β = 0.006, P = 0.954; 95% CI, -0.074-0.078)., Conclusion: Appetite was associated with family networks. Among social networks, focusing on family networks may help prevent the loss of appetite in older adults in Japan., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 Elsevier Inc. All rights reserved.)
- Published
- 2024
- Full Text
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50. Differential effects of nutritive and non-nutritive sweet mouth rinsing on appetite in adults with obesity.
- Author
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Cogan B and Cooper JA
- Subjects
- Adult, Humans, Male, Female, Adolescent, Young Adult, Ghrelin, Cross-Over Studies, Obesity, Sucrose pharmacology, Energy Intake, Cholecystokinin, Water pharmacology, Blood Glucose, Insulin, Appetite, Mouthwashes pharmacology
- Abstract
Background: Excessive added sugar intake has been associated with obesity; however, the effect of dietary sweetness on energy intake (EI) and appetite in adults with and without obesity has not yet been determined., Objective: To assess the effect of mouth rinses with and without energy and sweetness on measures of appetite, and to compare responses between subjects with body mass index (BMI) between 18.5 and 24.9 kg/m
2 or ≥30 kg/m2 ., Methods: In this randomized, double-blind crossover study, 39 subjects (age 23±5y; 17 male, 22 female; BMI 18.5-24.9 kg/m2 : n = 21; ≥30 kg/m2 : n = 18) performed modified sham-feeding (MSF) with a mouth rinse containing either sucrose, sucralose, maltodextrin, or water for 2min before expectorating the solution. Blood sampling and subjective appetite assessments occurred at baseline (-5) and 15, 30, 60, and 90min post-MSF. After, EI was assessed at a buffet meal and post-meal appetite ratings were assessed hourly for 3h., Results: Post-MSF ghrelin increased for water vs. maltodextrin (water: p = 0.03). Post-MSF cholecystokinin increased following maltodextrin-MSF (p = 0.03) and sucralose-MSF (p = 0.005) vs. sucrose for those with BMI:18.5-24.9 kg/m2 only. There was greater post-MSF desire to eat in response to water vs. sucrose (p = 0.03) and reduced fullness with sucralose for those with BMI≥30 vs. 18.5-24.9 kg/m2 (p < 0.001). There was no difference in EI at the buffet meal by mouth rinse (p = 0.98) or by BMI (p = 0.12). However, there was greater post-meal fullness following sucralose-MSF vs. water (p = 0.03) and sucrose (p = 0.004) for those with BMI≥30 vs. 18.5-24.9 kg/m2 ., Conclusion: Sucralose rinsing led to greater cephalic phase CCK release in adults with a BMI:18.5-24.9 kg/m2 only; however, ghrelin responses to unsweetened rinses were energy-specific for all adults. As subsequent EI was unaffected, further investigation of cephalic phase appetite is warranted., Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (Copyright © 2023 Elsevier Ltd. All rights reserved.)- Published
- 2024
- Full Text
- View/download PDF
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