1. Generalized anxiety disorder: some biochemical aspects.
- Author
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Munjack DJ, Baltazar PL, DeQuattro V, Sobin P, Palmer R, Zulueta A, Crocker B, Usigli R, Buckwalter G, and Leonard M
- Subjects
- Adolescent, Adult, Aged, Anxiety Disorders drug therapy, Anxiety Disorders psychology, Chlordiazepoxide therapeutic use, Female, Humans, Male, Middle Aged, Personality Tests, Propranolol therapeutic use, Anxiety Disorders blood, Epinephrine blood, Glycols blood, Methoxyhydroxyphenylglycol blood, Norepinephrine blood
- Abstract
Fifty-one patients who met DSM-III criteria for generalized anxiety disorder, and who were recruited to participate in a drug outcome study, filled out a variety of rating scales and had blood samples drawn for plasma norepinephrine, epinephrine, and free 3-methoxy-4-hydroxyphenylglycol (MHPG) after a 20-min rest period. This group was compared to 15 normal controls who also had their blood drawn after a 20-min rest period. While the two groups were initially found to have significantly different levels of plasma free MHPG through the use of t tests, this finding was not confirmed by subsequent discriminant analysis.
- Published
- 1990
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