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L-theanine is an amino-acid found in green tea (Camellia sinensis), a beverage consumed by people all around the world. Its chemical structure is similar to L-glutamic acid. L-theanine acts as an antagonist of AMPA and kainate receptors as well as partial co-agonist of the NMDA receptors. The application may be associated with several health benefits, such as improvements in cognition, reduction of stress and anxiety-like symptoms. Although the dosage of L-theanine in green tea, which is around 20 mg per tea, is not very likely to have meaningful impact on mental health, supplementation of doses 200-400 mg/day has shown some promising advantages. Despite some evidence towards beneficial impact of L-theanine on mental health, longer-term and larger cohort clinical studies are required in order to justify its application for patients suffering from such diseases as anxiety, depression, bipolar disorder, schizophrenia and sleep disorders. What is more, it is more possible to act as a therapy augmentation in particular cases, rather than conventional therapy replacement.

Introduction and purpose: The main aim of our study is to summarise existing knowledge and draw conclusions about the impact of magnesium deficiency on the occurrence of anxiety. Methodology: The literature available in the National Library of Medicine database at https://pubmed.ncbi.nlm.nih.gov and Google Scholar was reviewed. Articles were searched by using keywords: magnesium, deficiency, supplementation, anxiety disorders. Forty-seven research papers and meta-analyses were analysed. Description of the state of knowledge: Magnesium is an extremely important mineral in the human body involved in many physiological processes. A deficiency of this element affects the whole body and can cause mental disorders - including anxiety disorders. There are many theories showing a link between magnesium and anxiety disorders in both humans and animals. Magnesium has been shown to influence the function of neurotransmitters affecting the experience of anxiety. Supplementation in people with hypomagnesaemia has been proven to improve their health and well-being. However, it should be noted that supplements on the market vary in the bioavailability of the mineral, and the frequency of intake and dosage also affect the bioavailability of magnesium. Conclusions: It is important to ensure adequate levels of magnesium in the diet, given its impact on the proper functioning of the human body (including the nervous system) and the fact that most people consume insufficient amounts of this macronutrient. Evidence of a link between magnesium levels and anxiety has led to increased interest in the potential efficacy of magnesium supplementation to alleviate anxiety symptoms.