1. Oseltamivir-resistant pandemic (H1N1) 2009 virus infections, United States, 2010-11.
- Author
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Storms AD, Gubareva LV, Su S, Wheeling JT, Okomo-Adhiambo M, Pan CY, Reisdorf E, St George K, Myers R, Wotton JT, Robinson S, Leader B, Thompson M, Shannon M, Klimov A, and Fry AM
- Subjects
- Adult, Antiviral Agents pharmacology, Female, Humans, Influenza A Virus, H1N1 Subtype isolation & purification, Influenza, Human drug therapy, Influenza, Human mortality, Influenza, Human virology, Male, Oseltamivir pharmacology, Prevalence, United States epidemiology, Antiviral Agents therapeutic use, Drug Resistance, Viral, Influenza A Virus, H1N1 Subtype drug effects, Influenza, Human epidemiology, Oseltamivir therapeutic use, Pandemics
- Abstract
During October 2010-July 2011, 1.0% of pandemic (H1N1) 2009 viruses in the United States were oseltamivir resistant, compared with 0.5% during the 2009-10 influenza season. Of resistant viruses from 2010-11 and 2009-10, 26% and 89%, respectively, were from persons exposed to oseltamivir before specimen collection. Findings suggest limited community transmission of oseltamivir-resistant virus.
- Published
- 2012
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