1. [Reduction of hematogenous infection in HIV positive patients following highly active antiretroviral therapy].
- Author
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Luisa Pedro-Botet M, Maria Mòdol J, Vallés X, Reynaga E, Romeu J, Juan M, Sopena N, and Sabriá Leal M
- Subjects
- Adult, Anti-HIV Agents therapeutic use, CD4 Lymphocyte Count, Female, HIV Infections immunology, Humans, Male, AIDS-Related Opportunistic Infections epidemiology, Antiretroviral Therapy, Highly Active, HIV Infections drug therapy, Sepsis epidemiology
- Abstract
Background: Bloodstream infections have probably decreased in HIV patients since highly active antiretroviral therapy (HAART) usage., Patients and Method: Hematogenous infections, including mycobacteria and fungi in HIV patients, stratified into two periods (I: 1995-1996 and II: 1997-1998) were included to evaluate changes attributable to HAART., Results: 226 episodes were attended (incidence: 38.8 in period I and 15.3 in period II; p < 0.01). A significant decrease was observed in immunosuppression related microorganisms. HAART usage increased from 6.4% in period I to 31.2% in period II. Immunological parameters of HIV patients significantly improved in period II., Conclusions: Hematogenous infections have significantly decreased in HIV patients since the use of HAART.
- Published
- 2001
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