1. Superoxide dismutase enzyme and thiol antioxidants in gingival crevicular fluid and saliva
- Author
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Shermin Karim, P K Pratibha, Shobha Kamath, G Subraya Bhat, Ullas Kamath, Babi Dutta, Naveen Sharma, B Archana, K Mahalinga Bhat, and Vasudev Guddattu
- Subjects
Antioxidants ,gingival crevicular fluid ,gingivitis ,periodontitis ,saliva ,superoxide dismutase ,Dentistry ,RK1-715 - Abstract
Background: The possibility of impaired antioxidant status and so increased oxidative damage in periodontal disease is being conjectured. The present randomized controlled study was carried out with the objective of analyzing the activity of superoxide dismutase enzyme and thiol antioxidants in gingival crevicular fluid (GCF) and saliva as indicators of response to periodontal therapy. Materials and Methods: Subjects were screened and randomly divided into three groups: 23 periodontally healthy controls, 24 with gingivitis, and 23 with periodontitis. Based on the clinical attachment levels, the periodontitis group was further divided into subgroups, including mild, moderate, and severe periodontitis. GCF and saliva samples were collected for estimation of superoxide dismutase and thiol antioxidant concentrations at baseline and 15 days after nonsurgical treatment. Intragroup comparisons were statistically analyzed using repeated measures analysis of covariance (P value
- Published
- 2012
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