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It is hypothesized that apples of 2 Brazilian cultivars with different content of sugars and antioxidant compounds promote similar effects on the antioxidant status and lipid peroxidation in human serum after acute intake. Nine healthy women ingested 300 mL of Golden Delicious or Catarina apple juice (AJ) or water, and blood samples were collected before and 1 hour after intake. After intake of both AJ, a similar and significant increase in serum antioxidant capacity and ascorbic and uric acid levels and a significant decrease in serum lipid peroxidation was observed. The increase in serum antioxidant capacity after consumption of both AJ was correlated directly with the uric acid levels and inversely with serum lipid peroxidation. In summary, the acute intake of AJ of 2 cultivars promoted a similar effect on the antioxidant status and lipid peroxidation in human blood serum., (Copyright © 2012 Elsevier Inc. All rights reserved.)

Objectives: To assess the effect of a nutrition education intervention on nutritional factors and oxidative stress during treatment of breast cancer. Design: Nonrandomized clinical trial conducted in 2010-2011, including an evaluation at baseline and after 12 months. Participants: Women from Brazil who had breast cancer, divided into an intervention group (IG) (n = 18) and comparison group (n = 75). Intervention: To increase intake of fruits and vegetables and reduce red and processed meats, via telephone and printed materials. Main Outcome Measures: Food intake, anthropometry, and levels of lipid hydroperoxide, carbonyl proteins, reduced glutathione, and ferric reducing antioxidant power. Analyses: Chi-square, Mann--Whitney or t tests for baseline data; Wilcoxon or paired t tests for intragroup outcomes, linear regression models, and Bonferroni multiplicity adjustment. Results: The researchers observed an increase in fruit and vegetable intake, reduction in red and processed meat intake, no change in body weight, and an increase in glutathione in the IG over the comparison group. However, after Bonferroni adjustment, only the consumption of fruits and vegetables and fruit was significantly higher in IG. Conclusions and Implications: This study presents improved dietary changes after a theory-driven nutrition education intervention. Although the sample size is small, it has proven to be clinically relevant. [ABSTRACT FROM AUTHOR]