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The objective of this work was to study lactic fermentation as a biostrategy to enhance the antioxidant activity of oats. The adaptability of 31 strains of lactic bacteria (LB) in an oats/water system (OWS/SAA) was evaluated, measuring growth, acidification and fermentation activity (impedimetric method; detection time [DT], maximum rate of conductance change [MRCC/VMCC] and percentage of conductance change [PCC]). Moreover, the content of phenolic compounds (PC) was determined using the Folin-Ciocalteu method (gallic acid equivalents [GAE]), free peptides and amino acids and free radical scavenging activity (DPPH • and ABTS •+ methods) of methanolic and aqueous extracts obtained from fermented OWS/SAAs (fOWS/SAAf) were determined. Six strains have shown the best adaptability to SAA, with high values of VMCC (0.34-0.47 μS/min) and PCC (53.6-66.6%), and low values of DT (≤ 3 h). In these f/OWS/SAAf the chemical composition was also modified (PC concentration, peptides and free amino acids) with strain-dependent behavior. The PC content in f/OWS/SAAf using these six strains (29.1-36.9 μg GAE/ml) was higher than the control content in OWS/SAA control (17.1 ± 1.9 μg GAE/ml). An increase (9-25.5%) in antioxidant activity in f/OWS/SAAf methanolic extracts was detected using both methods. Minor modifications were observed in the peptide and free amino acid content of SAA and their antioxidant activity. Our results show LB ability to adapt to oat as fermentation substrate and increase the content of its antioxidant compounds., (Copyright © 2021 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.)

Introduction and Objective: Oxidative stress appears to play a critical role in the pathogenesis of preeclampsia. Evidence suggests that adequate intake of antioxidants can modulate this condition. The objective of this study was to assess the intake of antioxidant nutrients and coefficients of variation in pregnant women with preeclampsia., Methods: In a cross-sectional study in the public health network of the city of Maceió, Brazil, a dietary survey was performed consisting of 24-hour food recalls, with subsequent adjustment of nutrients using the estimated average requirement as the cutoff point, and a questionnaire on frequency of consumption of antioxidants., Results: We studied 90 pregnant women with preeclampsia (PWP) and 90 pregnant women without preeclampsia (PWoP) with mean ages of 25.8±6.7 years and 24.1±6.2 years (p=0.519), respectively. A low mean intake of antioxidants (vitamin A, selenium, zinc and copper) was observed in both PWP and PWoP, although intakes of vitamin A (p=0.045) and selenium (p=0.008) were higher in PWoP. In addition, we observed high coefficients of variation in nutrient intakes in both groups, which were higher for vitamin C (p<0.001), vitamin A (p=0.006) and copper (p=0.005) in PWP., Conclusions: Consumption of antioxidant nutrients by pregnant women with preeclampsia is inadequate, with considerable daily variations in intake, which points to a need for nutrition education strategies aimed at improving intakes, because diet is without doubt a key factor in the modulation of oxidative stress caused by preeclampsia., (Copyright © 2016 Sociedade Portuguesa de Cardiologia. Publicado por Elsevier España, S.L.U. All rights reserved.)

Introduction: Several approaches have been tried for the treatment of tinnitus, from cognitive-behavioral therapies and sound enrichment to medication. In this context, antioxidants, widely used in numerous areas of medicine, appear to represent a promising approach for the control of this symptom, which often is poorly controlled., Objective: To evaluate the effects of antioxidant therapy for tinnitus in a group of elderly patients., Methods: Prospective, randomized, double-blinded, placebo-controlled clinical trial. The sample consisted of 58 subjects aged 60 years or older, with a complaint of tinnitus associated with sensorineural hearing loss. These individuals completed the Tinnitus Handicap Inventory (THI) questionnaire before and after six months of therapy. The treatment regimens were: Ginkgo biloba dry extract (120mg/day), α-lipoic acid (60mg/day)+vitamin C (600mg/day), papaverine hydrochloride (100mg/day)+vitamin E (400mg/day), and placebo., Results: There was no statistically significant difference between THI by degree (p=0.441) and by score (p=0.848) before and after treatment., Conclusion: There was no benefit from the use of antioxidant agents for tinnitus in this sample., (Copyright © 2015 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.)

Introducción: la insuficiencia hepática fulminante (IHF) es un síndrome clínico poco frecuente, que se caracteriza por una disfunción hepática severa y repentina. La tioacetamida (TAA) es una hepatotoxina cuya administración puede inducir necrosis centrolobulillar en las células hepáticas y aumentar la formación de especies reactivas de oxígeno y la peroxidación lipídica en ratas. La glutamina es un precursor para la síntesis de glutatión. Objetivo: el objetivo del estudio es evaluar los efectos antioxidantes de la glutamina en un modelo de rata de IHF inducida por TAA. Métodos: ratas macho Wistar se dividieron en cuatro grupos de acuerdo con el tratamiento y el tiempo de evaluación: control, glutamina (25 mg/kg), tioacetamida (400 mg/kg) y tioacetamida más glutamina. Los animales se evaluaron después de 24, 36 y 48 horas. Se recogieron muestras de sangre para el análisis de los niveles de aspartato aminotransferasa (AST), alanina aminotransferasa (ALT), fosfatasa alcalina (AP), bilirrubina total (TB) y creatinina (CRE), y muestras de hígado para evaluar la peroxidación lipídica, las sustancias reactivas al ácido tiobarbitúrico (TBARS), la actividad de las enzimas antioxidantes superóxido dismutasa (SOD), glutatión peroxidasa (GPx), catalasa (CAT) y glutatión S-transferasa (GST). Además se midieron mediante inmunohistoquímica el factor nuclear kappa N (NF-κB), el fator de necrosis tumoral (TNF-α) y la óxido nítrico sintasa inducible (iNOS). Resultados: la TAA causó alteraciones en los parámetros bioquímicos e histológicos, y el aumento de los marcadores del proceso inflamatorio. Los niveles de TBARS y la actividad de SOD y GST fueron significativamente inferiores en los grupos de glutamina en comparación con TAA. La actividad de CAT se incrementó en los animales tratados con glutamina en comparación con la TAA. La actividad GPx también fue menor a las 36 y 48 h en los animales tratados com glutamina. El daño tisular y la expresión de NF-κB, TNF-α e iNOS fueron significativamente inferiores en los animales tratados con glutamina. Conclusión: la glutamina ha demostrado tener efectos protectores contra el daño hepático en un modelo de IHF inducida por TAA en la rata.

Background and Objective: Obesity is characterized by a generalized increase of adipose tissue, high production of adipocytokines and presence of oxidative systemic stress. The objective of this study was to evaluate the changes generated in the oxidative stress and anthropometric parameters in obese subjects by the prescription of a hypocaloric diet in combination with moderate aerobic exercise and supplementation with antioxidants., Patients and Methods: Oxidative damage was determined in the plasma from 30 normal weight and 30 obese subjects. Three groups of treatment were established: Hypocaloric diet (HD), HD plus moderate aerobic exercise (HDE) and HDE plus antioxidants (DHEA). Biomarkers of oxidative stress (thiobarbituric acid reactive substances [TBARS], carbonyl groups, dityrosine) and anthropometric parameters were determined., Results: Higher values of biomarkers of oxidative damage were observed in obese (TBARS 13.74 ± 1.2 μM; carbonyl groups 0.89 ± 0.04 nmol of osazone/mg of protein; dityrosine 478.9 ± 27.4 RFU/mg of protein) in comparison to normal weight subjects (TBARS 7.08 ± 0.8 μM; carbonyl groups 0.65 ± 0.04 nmol of osazone/mg of protein; dityrosine 126.3 ± 12.6 RFU/mg of protein), thus showing the presence of an oxidative damage. The prescription of HD decreased the oxidative damage and anthropometric parameters in the obese subjects. We did not observe additional benefit effects on these determinations with HDE or HDEA treatments., Conclusions: We demonstrated that an HD decreases the oxidative damage in obese subjects. Oxidative stress is an important factor in the development of comorbidity in obesity. Therefore, the prescription of a HD could be a key issue in the treatment of the disease., (Copyright © 2013 Elsevier España, S.L.U. All rights reserved.)

Objective: the present study was conducted to investigate the oxidant-antioxidant status in Egyptian children with sickle cell anemia., Methods: the serum levels of total antioxidant capacity (TAO), paraoxonase (PON), vitamin E, nitrite, and malondialdehyde (MDA) were measured in 40 steady state children with homozygous sickle cell anemia (24 males and 16 females) and 20 apparently healthy age- and gender-matched controls., Results: mean serum TAO, PON, vitamin E, and nitrite levels were significantly lower in the group with sickle cell anemia, whereas mean serum MDA was significantly higher in these children compared to controls. No significant differences in mean levels of TAO, PON, nitrite, vitamin E, and MDA were found in sickle cell anemia patients receiving hydroxyurea when compared with those not receiving hydroxyurea. A significant negative correlation between serum nitrite and the occurrence of vaso-occlusive crises (VOC) was observed (r=-0.3, p=0.04). PON level was found to be positively correlated with patients' weight and BMI (r=-0.4, p=0.01; r=-0.7, p<0.001, respectively), but not with frequency of VOC. The area under the curve of serum nitrite in predicting occurrence of VOC was 0.782, versus 0.701 for PON, and 0.650 for TAO (p=0.006). Serum MDA was not correlated with nitrite, PON, TAO, or vitamin E levels. No significant correlations were detected between serum nitrite and hemoglobin or antioxidant enzymes., Conclusion: children with sickle cell anemia have chronic oxidative stress that may result in increased VOC, and decreased serum nitrite may be associated with increases in VOC frequency. A novel finding in this study is the decrease in PON level in these patients, which is an interesting subject for further research., (Copyright © 2014 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.)

Background: Antioxidants of natural origin can be used to improve cryopreservation of semen. Objective: To evaluate the effect of dietary supplementation with Erythrina americana on the seminal characteristics of rams. Methods: Ten rams were randomly distributed in two treatments: l) Group supplemented with E. americana (20% dry matter basis; AEA, n=5), and 2) Control group not supplemented (SEA, n=5). Both diets were iso-proteic and iso-energetic. The feeding period was eleven weeks. Ejaculates were obtained through an artificial vagina and were evaluated fresh (37 °C) and refrigerated (5 °C). Semen volume (VOL) was assessed by visual examination in a calibrated (mm) tube; sperm concentration (CON x106) with a photometer; and mass motility (MM, 1-5), individual motility (IM), normality (N), and live sperm (L) were assessed by microscopic observation. Results: Feeding E. americana did not affect (p>0.05) VOL, CON, MM, and N in fresh semen, but decreased (p<0.05) IM and L. The L and N variables did not differ (p>0.05) among treatment groups in the refrigerated semen; however, IM improved in the AEA group (p<0.05) compared to the SEA group. Conclusion: Dietary supplementation of rams with E. americana reduces sperm quality in fresh semen but is beneficial for the cooling process of refrigerated semen. [ABSTRACT FROM AUTHOR]

The aim of this study was to develop and characterize reduced-fat ice cream formulations with the addition of dehydrated cassava bagasse (CB) and lychee pulp (LP). The ice cream formulations were prepared with different proportions of palm fat (0 to 5%), CB (0 to 5%) and LP (1 to 8%) and were evaluated in terms of chemical and microbiological composition, and in relation to the technological, antioxidant and sensory properties. The use of higher levels of CB (5%) and LP (8%) allowed obtaining a higher fiber content and lower fat content. All formulations were safe for consumption and showed adequate values for overrun, melting rate and color. The ice creams showed adequate sensory acceptance, with emphasis on the formulations containing different amounts of CB addition (2 to 5%) and until 3% LP. The higher LP content the higher total phenolic content and the antioxidant capacity were found in ice cream formulations. These results showed the viability of applying CB and LP in ice cream formulations, especially in the proportion of 5% and 1%, promoting the sustainability by using a natural source of antioxidants and a fiber-rich agro-industrial by-product. [ABSTRACT FROM AUTHOR]

Background: Ethanol consumption during pregnancy induces enduring detrimental effects in the offspring, manifesting as a spectrum of symptoms collectively termed as Fetal Alcohol Spectrum Disorders (FASD). Presently, there is a scarcity of treatments for FASD.Objectives: To analyze current literature, emphasizing evidence derived from preclinical models, that could potentially inform therapeutic interventions for FASD.Methods: A narrative review was conducted focusing on four prospective treatments: nutritional supplements, antioxidants, anti-inflammatory compounds and environmental enrichment. The review also highlights innovative therapeutic strategies applied during early (e.g. folate administration, postnatal days 4–9) or late (e.g. NOX2 inhibitors given after weaning) postnatal stages that resulted in significant improvements in behavioral responses during adolescence (a critical period marked by the emergence of mental health issues in humans).Results: Our findings underscore the value of treatments centered around nutritional supplementation or environmental enrichment, aimed at mitigating oxidative stress and inflammation, implying shared mechanisms in FASD pathogenesis. Moreover, the review spotlights emerging evidence pertaining to the involvement of novel molecular components with potential pharmacological targets (such as NOX2, MCP1/CCR2, PPARJ, and PDE1).Conclusions: Preclinical studies have identified oxidative imbalance and neuroinflammation as relevant pathological mechanisms induced by prenatal ethanol exposure. The relevance of these mechanisms, which exhibit positive feedback loop mechanisms, appear to peak during early development and decreases in adulthood. These findings provide a framework for the future development of therapeutic avenues in the development of specific clinical treatments for FASD. [ABSTRACT FROM AUTHOR]

Environmental pollution can promote oxidative stress by exposing the body to various elements and substances that generate free radicals, such as lead and vanadium. These free radicals can negatively impact the respiratory, cardiovascular, immune, and neurological systems of vulnerable populations, including children, the elderly, and those with chronic diseases. To prevent or reduce oxidative stress, it is recommended to consume a balanced diet rich in natural antioxidants. These antioxidants can be found in various foods, especially in fruits and vegetables with intense colors, seeds, and spices. In recent decades, the effectiveness of consuming natural antioxidants such as resveratrol (found in wine), coffee, curcumin, garlic, vitamin C, vitamin E, and green tea has been demonstrated. These antioxidants have beneficial effects on the body, including the protection of cell membranes, regulation of gene expression associated with inflammation, prevention or reduction of endothelial damage, and the decrease or diminished severity of neurodegeneration, liver, and pulmonary disorders. Additionally, they stimulate the immune response. [ABSTRACT FROM AUTHOR]

Copyright of Revista Nutrición Clínica y Dietética Hospitalaria is the property of Sociedad Espanola de Dietetica y Ciencias de la Alimentacion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas is the property of Universidad de Santiago de Chile and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The aim of this study was to evaluate the effect of different levels of dehydrated squash pulp (DSP) (0, 5, 10, 15, and 25 g·100 g-1 of flour) and drying temperatures (50 and 60 °C) on the quality characteristics of spaghetti, i.e., dietary fiber, total carotenoid content, color, cooking quality, texture parameters, and sensory acceptance. The results showed that DSP has a total carotenoid content of 44.42 to 277.90 µg·g-1 and fiber content of 2.45 to 12.40 g·100 g-1. Additionally, the DSP level decreased the cooking time, increased the loss of solids, and generated a decrease in the fracture, hardness, and elasticity of the spaghetti. Furthermore, the increase from 50 to 60 °C in the drying temperature increased the content of carotenoids up to 6.4%, improving the texture properties while not significantly affecting the cooking quality. The spaghetti formulations containing 5 and 10 g·100 g-1 of DSP resulted in improved sensory acceptance. It was possible to develop a new spaghetti type by adding dehydrated squash pulp with better nutritional characteristics such as high dietary fiber content and antioxidants. [ABSTRACT FROM AUTHOR]

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Copyright of Revista Foco (Interdisciplinary Studies Journal) is the property of Revista Foco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Green tea, or Camellia sinensis, is a type of unfermented tea that contains natural substances found in fresh leaves. It is considered the second most popular drink in the world after water. This review extensively examines the phytochemistry of green tea, as it exhibits antioxidant, anticancer, hypoglycemic, antibacterial, antiviral and neuroprotective pharmacological activities. Consequently, green tea has demonstrated promising practical applications for healthcare and disease prevention. To accomplish this, a search was conducted using bibliographic databases such as PubMed, Cochrane, and Web of Science to find articles related to the phytochemistry of green tea published between 2018 and 2023, in order to ascertain, with evidence, the properties of green tea. [ABSTRACT FROM AUTHOR]

Objective: To identify the influence of carbohydrate (CHO) intake on oxidative status among women with and without gestational diabetes mellitus (GDM). Materials and methods: A cross-sectional, observational and comparative study was carried out with two groups of 21 women each with and without GDM in the city of Toluca, Mexico, from January to December 2022. The sociodemographic parameters were determined by administering the patients a medical history questionnaire; anthropometric parameters such as body weight and height were measured; and biochemical parameters including total cholesterol (TC) and triglycerides (TG) were calculated. The oxidant/antioxidant status was assessed as follows: malondialdehyde (MDA) as oxidative stress marker; and catalase (CAT), superoxide dismutase (SOD) and total antioxidant capacity (TAC) as antioxidants. Dietary habits were evaluated through a 24-hour reminder in both groups of women to obtain the macronutrient classes, i.e., proteins, fats and CHOs. Based on the total carbohydrates (TCHOs), complex (CCHOs) and simple carbohydrates (SCHOs) such as sucrose were calculated. SCHOs per day were measured using the list of foods with sucrose content per 100 grams according to the Mexican Food Equivalence System (SMAE). The NutriKcal VO program was used for the dietary analysis. Statistical tests such as Student's t test and Mann-Whitney U test were performed for the independent samples and nonhomogeneous variables, respectively, and Spearman's rank correlation coefficient (p < 0.05) was determined using the IBM SPSS Statistics V19. Results: The results showed that the difference between the levels of TC (p < 0.029), TG (p < 0.029), enzymes CAT (p < 0.011) and SOD (p < 0.013), as well as MDA (p < 0.039) was significantly higher among patients in the group with GDM compared to that in the group without GDM. In addition, the group with GDM consumed a higher proportion of sucrose. Conclusions: Women with GDM have an imbalance in the oxidant/antioxidant status, influenced by the type of CHO they consume, particularly SCHOs such as sucrose. [ABSTRACT FROM AUTHOR]

Laelia speciosa is an epiphytic orchid endemic to Mexico, enjoying special protected status due to illegal sales and clandestine field extraction. Until now, in vitro cultivation of this plant has not been explored using temporary immersion bioreactor (TIB). L. speciosa seedlings were grown in a TIB, and the presence of bioactive compounds released into the liquid culture medium was determined. Bioactive compounds such as antioxidants, total polyphenols, and flavonoids were identified. The maximum concentration of total polyphenols was 2.29 ± 0.10 mg GAE/g, and the antioxidant capacity reached 33.7 %. Colorimetric tests revealed the presence of flavanones and flavonols. Gas chromatography-mass spectrometry identified components of the culture medium as 1,3- dihydroxyacetone dimer and 5-(hydroxymethyl)-2-furancarbaldehyde. Fourier transform infrared spectroscopy confirmed the presence of polyphenols in the culture medium. This work provides an alternative method for obtaining bioactive compounds while conserving L. speciosa seedlings. [ABSTRACT FROM AUTHOR]

The human microbiota is highly variable, it is interrelated between organs and systems. This is the case of the gut-brain and skin axis, whose dysbiosis or imbalance in its bacterial phylotypes can be conditioning factors for dermatoses such as acne. Acne is the most common disease in adolescents, multiple anti-inflammatory treatments have been investigated to treat this part of its pathophysiology, among which are tetracyclines at suboptimal doses, antioxidants and oral probiotics. Based on the current literature, there is evidence to suggest that oral probiotics may be effective as adjunctive therapy to control acne. Given the aggressiveness of some standard acne treatments, probiotics should continue to be investigated as an alternative or adjuvant therapy, as they are not safe in immunosuppressed patients. Larger studies looking at probiotic supplementation along with medications are needed to understand the true advantages and disadvantages of their prescription. [ABSTRACT FROM AUTHOR]

Copyright of MESO is the property of Zadruzna Stampa D.D. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Cientifica de la Facultade de Veterinaria is the property of Universidad del Zulia, Facultad de Ciencias Veterinarias and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

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Copyright of Informacion Tecnica Economica Agraria is the property of Asociacion Interprofesional para el Desarrollo Agrario (AIDA) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The effects of cold and hot smoking and the addition of Dunaliella salina polyphenol extract on the biochemical quality and shelf-life of Sander lucioperca fillets after storage for 90 days at 0-4 °C were examined. The results showed a significant increase in protein, lipid, free fatty acid, and 1,1-diphenyl-2-picrylhydrazyl contents, and a decrease in peroxide and thiobarbituric acid reactive substances, and volatile base nitrogen levels in cold (CSF) and hot (HSF) smoked fillets covered with or without extract and stored for 1, 20, and 90 days compared to fresh fillets (FF). Saturated and monounsaturated fatty acids exhibited a significant increase in FF and CSF and HSF covered with or without extract. The total polyunsaturated fatty acids revealed a significant decrease in FF and CSF and HSF with or without extract. Therefore, cold and hot smoking and polyphenol extract improved the biochemical quality and storage shelf-life of fillets for 90 days at 0-4 °C. [ABSTRACT FROM AUTHOR]

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Hops (Humulus lupulus L.) is a plant whose female inflorescence is used in the brewing industry to impart bitterness and aroma to the drink, and Brazil imports about 98% of this raw material. However, this plant has been gaining prominence in the country, directly influencing the quality characteristics of the final product. Thus, the aim of this study was to explore the relationship between the alpha acids content of two hop cultivars produced in Brazil and the United States. The work was developed at UDESC/CAV, in Lages/SC, in the year 2021. A standard Indian Pale Ale beer, with the same base recipe, was produced. Each treatment consisted of the addition of different hop cultivars (Comet and Fuggle) from two origins (Brazilian and American). The results confirm that the cultivars and the origin of the hops influence the chemical characteristics of the evaluated beers. The amount of total phenolic compounds, flavonoids and antioxidant activity of the beer produced with the Brazilian Fuggle cultivar was 6.5% (850.09 meq gallic acid L-1); 75.5% (95.07 meq quercetin L-1) and 13.8% (6890 mmol Trolox L-1) higher, respectively, in relation to beer produced with the same cultivar originating in the United States. There was an inverse correlation between the alpha acid content and the phenolic content and antioxidant capacity of the beers. The beers in which Brazilian Fuggle hops were used, with the lowest alpha acid content among those adopted, showed a greater positive association with the total polyphenol content, individuals and antioxidant capacity of the beers. In conclusion, the beers produced with the cultivar Fuggle Brasileiro have a greater concentration of antioxidant substances.. [ABSTRACT FROM AUTHOR]

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Copyright of Revista Nutrición Clínica y Dietética Hospitalaria is the property of Sociedad Espanola de Dietetica y Ciencias de la Alimentacion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Nutrición Clínica y Dietética Hospitalaria is the property of Sociedad Espanola de Dietetica y Ciencias de la Alimentacion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of MESO is the property of Zadruzna Stampa D.D. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista de Investigación en Salud VIVE is the property of Revista de Investigacion en Salud VIVE and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista de Investigación en Salud VIVE is the property of Revista de Investigacion en Salud VIVE and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Free radicals are compounds characterized by having an unpaired electron in their outer orbit, a condition that makes them highly reactive, i.e., they interact through diffusion-controlled reactions with proteins, lipids and nucleic acids. They have also been referred to as reactive oxygen species (ROS), reactive nitrogen species (RNS) or reactive sulfur species (RSS). In the human organism, they are mainly produced in the mitochondrial electron transport chain, where respiratory complexes I and III specifically participate and reduce oxygen by converting it into superoxide anion. Likewise, they can be formed through a wide variety of enzymatic and non-enzymatic reactions involving substances that are synthesized by cells or are ingested with food and some medicines. Human beings have an antioxidant system which is both enzymatic and non-enzymatic in nature and whose function is to protect the organism from the harmful action of free radicals. This system includes enzymes--such as catalase, superoxide dismutase, thioredoxin, etc.--and non-enzymatic compounds--such as glutathione, ferritin, myoglobin, etc. However, they are not efficient enough to protect it, so it is necessary to eat foods that contain substances with antioxidant properties whose protective action will depend on their chemical reactivity and their concentration. These antioxidant compounds are mainly found in fruits and vegetables, where polyphenols, flavonoids, carotenoids, vitamin C, vitamin E, etc. have been identified. A significant amount of evidence suggests that the intake of antioxidant substances protects the body from the damaging effect of free radicals, but when the oxidative action prevails over the antioxidant action, it can lead to oxidative stress, a condition that is closely linked to a wide variety of chronic non-communicable diseases including cancer, diabetes mellitus, obesity, psoriasis, atherosclerosis, among others. All this seems to indicate that the term "cellular redox steady state" more appropriately describes the constant adaptation to a situation of rapid chemical turnover and suggests that the substances involved in this process be designated as "biologically reactive species" due to the existence of harmful compounds such as hydrogen peroxide, peroxynitrite, etc., which are not--strictly speaking--free radicals but have toxic effects on cells. [ABSTRACT FROM AUTHOR]

The damage produced by cryopreservation processes on ovine spermatozoa reduces semen quality and therefore its fertilising capacity. The aim of this study was to evaluate the effect of adding different concentrations of 3,4-dihydroxyphenylglycol (DHPG) to sheep semen during the cryopreservation process. For this purpose, the sperm, once collected, were pooled and diluted with Biladyl, supplemented with different concentrations of DHPG (59 µM, 177µM, 295µM and 413µM), leaving a control treatment without antioxidant supplementation. Motility, viability, acrosome integrity, mitochondrial membrane potential and lipid peroxidation (LPO) were assessed. No significant differences were observed derived from the addition of DHPG for all the studied variables, with the exception of the LPO, which was reduced in comparison to the control treatment when the samples were cryopreserved. It was therefore concluded that the addition of DHPG has a positive effect on thawed sperm as they reduced LPO. [ABSTRACT FROM AUTHOR]

The aim of this study is to investigate the ability of oleuropein-rich olive leaf extract (OLE) to improve the quality and oxidative stability of sunflower oil subjected to accelerated thermal oxidation. Oleuropein was the major phenolic compound determined by HPLC-DAD with a content ranging from 20.81 to 32.56 mg·g1 of dry extract (DE). The evaluation of the in vitro antioxidant capacity of OLE showed good scavenging capacity of the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) and hydrogen peroxide (H2O2) (1.01 and 0.96 mmol Trolox equivalents (ET·g-1 DE, respectively). The enrichment of sunflower oil with 0.1, 0.25 and 0.5% OLE (w/v) significantly inhibited thermal-induced peroxidation in a dose-dependent fashion. 0.25% OLE was the most effective concentration and showed a significant reduction in peroxide value and conjugated dienes by 61.4 and 17.4%. These results indicate that OLE can be considered a good natural alternative for extending the shelf-life of polyunsaturated vegetable oils. [ABSTRACT FROM AUTHOR]

Aging is an inevitable physiological process. However, when people undergo this process, they want to delay their signs and symptoms as much as possible. Wrinkles, expression lines, dyschromia, and skin sagging can be highlighted among these symptoms. Thus, the demand for cosmetics, which prevent and treat the signs of aging, is increasing. The cupuaçu butter is among the active ingredients used for this purpose. Cupuaçu butter is a triglyceride that has a balanced content of saturated and unsaturated fatty acids in its composition. Its use in the cosmetic industry is due to its anti-inflammatory, moisturizing, antioxidant emollient, and lubricating properties. In this context, the objective of this study was to analyze, through an integrative descriptive review with a qualitative approach, the potential use and benefits of cupuaçu butter as an active ingredient in preventing aging. In conclusion, cupuaçu butter is a potential cosmetic asset, due to its antioxidant and humectant properties, which act by preventing oxidative stress from occurring and moisturizing the skin, respectively. [ABSTRACT FROM AUTHOR]

The presence of sargassum on the Caribbean coast causes ecological problems, as does the sludge from water treatment plants. Fertilizers like Nutrkam (sargassum extract) and Biofertex (leachate from the vermicomposting of sludge from a textile plant) have been prepared from these two materials. Both biostimulants were applied to a lettuce crop in a greenhouse, the doses were 2, 5, 7.5, 10 and 20% by volume, the results were compared with urea fertilization. At eight weeks, height, number of green leaves and senescent leaves, fresh and dry weight, antioxidant capacity, and flavonoid content were evaluated. With NutrKam at 5, 10 and 20% and Biofertex at 7.5, 10 and 20%, the height of the leaves was statistically equal to that obtained with urea; there was no significant difference in the weight of leaves when fertilizing with 20% NutrKam, 7.5% Biofertex and urea. With all the treatments, except with Biofertex at 10 %, the antioxidant content was higher than that of lettuces fertilized with urea. The use of both materials to prepare fertilizers is an attractive alternative, since on the one hand the pollution caused by their inadequate disposal is reduced, and on the other, their agricultural application would help reduce the use of chemical fertilizers, without impairing the yield and crop properties. [ABSTRACT FROM AUTHOR]

Background: Among the neurodegenerative diseases that cause dementia, Alzheimer's disease (AD) appears among the main ones, being responsible for around 50% to 70% of cases. The most currently used pharmacotherapy for the treatment of AD aims to minimize cognitive losses (learning and memory), as well as changes in mood and behavior, in addition to maintaining quality of life, improving function and independence. Aim: To synthesize evidence related to pharmacotherapy in the treatment of AD. Method: The search focused on literature that discussed the benefits and limitations of cholinergic replacement therapy, mainly represented by cholinesterase inhibitors, based on data from neurobiological, pharmacological and clinical research. Results and Discussion: The role of memantine in moderate to severe cases of dementia, as well as the prospects for its use in combination with cholinesterase inhibitors, were discussed in most of the papers reviewed. The role of estrogen replacement, antioxidants, statins and anti-inflammatories in the treatment and prevention of dementia was also addressed, taking into account the negative results of recent clinical epidemiological studies. Finally, the different modalities of anti-amyloid therapy were discussed, mainly considering immunotherapy in the treatment of AD. Conclusion: Pharmacotherapy used in AD currently includes cholinesterase inhibitors (AChEI), memantine, antioxidant drugs, estrogen, NSAIDs, statins, Ginkgo biloba and neuronal growth factor, among other drugs. The challenge of the moment is to identify new drugs that act in the treatment of already established AD, and avoid overlapping predisposing factors for the development of the disease, as well as improving the understanding of the triggering pathways of AD and establishing strategies to prevent its progression. [ABSTRACT FROM AUTHOR]

Copyright of Brazilian Journal of Biology is the property of Instituto Internacional de Ecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Brazilian Journal of Biology is the property of Instituto Internacional de Ecologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Revista Colombiana de Investigaciones Agroindustriales is the property of Revista Colombiana de Investigaciones Agroindustriales del Centro Agropecuario Sena Buga and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)