Search

WOS: 000393197500004, Objective: The antioxidant potential of various extracts were obtained from the leaf and fruit of Maclura pomifera (Rafin.) Schneider (Moraceae) along with its major isoflavonoids; osajin and pomiferin, their semi-synthetic derivatives; iso-osajin and iso-pomiferin and macluraxanthone, which were assayed. Methods: The extracts and compounds were subjected to six experimental models including 2,2'-diphenyl-1-picrylhydrazyl (DPPH), N, N-dimethyl-p-phenylendiamine (DMPD+), and nitric oxide (NO) radical scavenging activity, metal-chelating capacity, ferric-(FRAP) and phosphomolibdenum- reducing antioxidant power (PRAP) assays by using ELISA methods. Results: The fruit aqueous extract exerted higher scavenging activity against DMPD and NO radicals, while the fruit ethyl acetate extract was the most active against DPPH radical (68.61 +/- 2.53%). Among the tested compounds, the highest DPPH (91.74 +/- 0.26%) and DMPD (30.63 +/- 1.31%) radical scavenging effect was observed with macluraxanthone, while pomiferin and iso-pomiferin exhibited better activity than osajin and iso-osajin in all assays except the metal-chelation capacity assay. Phytol was the major compound in both the leaf oils, while the fruit essential oil contained beta-caryophyllene as the main component (69.3%). Discussion and Conclusion: The current study covers particularly antioxidant capacity of iso-osajin, iso-pomiferin, and macluraxanthone by the aforementioned methods and, among them; pomiferin seems to be a natural possible antioxidant agent., Scientific and Technological Research Council of Turkey (TUBITAK), F.S. Senol expresses her genuine appreciation to the Scientific and Technological Research Council of Turkey (TUBITAK) for the scholarship provided during her Ph.D. studies.

omiferin and osajin have been isolated from the acetonic extract of M. pomifera fruits. Effects of total acetonic extract, pomiferin and osajin on the autooxidation of purified sunflower triacylglycerol were studied. Pomiferin showed a high antioxidant activity whereas total acetonic extract showed moderate and osajin revealed a low activity.Se han aislado la pomiferina y la osajina del extracto de hexano del fruto de M. pomifera. Se han estudiado los efectos sobre la oxidación de triglicéridos purificados del aceite de girasol, del extracto de acetona, de la pomiferina y de la osajina. La pomiferina mostró una actividad antioxidante elevada en cambio, el extracto de acetona mostró una actividad moderada y la osajina baja.