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Your search keyword '"Shi, Lei-Ling"' showing total 2 results
Start Over Author "Shi, Lei-Ling" Topic antineoplastic agents
2 results on '"Shi, Lei-Ling"'

1. Four New Sesquiterpenoids from the Roots of Diarthron Tianschanica with Their Antineoplastic Activity.

Author

Sun DX, Zhao D, Wei HY, Ma XL, Shi LL, and Zhang J

Subjects
Antineoplastic Agents chemistry, Cell Line, Tumor, Chromatography, Gel, Chromatography, High Pressure Liquid, Humans, Inhibitory Concentration 50, Sesquiterpenes chemistry, Spectrum Analysis methods, Structure-Activity Relationship, Antineoplastic Agents pharmacology, Plant Roots chemistry, Sesquiterpenes pharmacology, Thymelaeaceae chemistry
Abstract

Four new sesquiterpenoids, known as diarthronchas A⁻D ( 1 ⁻ 4 ), and one known daphnauranol B ( 5 ) were isolated from the methanol extract of the roots of Diarthron tianschanica . The compounds structures were determined on the basis of spectroscopic data. All of the isolated compounds were profiled for their antineoplastic activity.

Published
2018
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2. Diarylpentanol constituents from the aerial part of Stelleropsis tianschanica.

Author

Shi, Lei-Ling, Ma, Guo-Xu, Gao, Hua-Chun, Chen, Quan-Cheng, Yang, Jun-Shan, Jia, Xiao-Guang, and Zhang, Jing

Subjects
*ALTERNATIVE medicine, *ANTINEOPLASTIC agents, *BIOLOGICAL assay, *BIOLOGICAL models, *PHYSICAL & theoretical chemistry, *CHROMATOGRAPHIC analysis, *DOSE-effect relationship in pharmacology, *MASS spectrometry, *MEDICINAL plants, *MOUTH tumors, *NUCLEAR magnetic resonance spectroscopy, *RESEARCH funding, *PLANT extracts, *PLANT anatomy, *DESCRIPTIVE statistics, *IN vitro studies, *PHARMACODYNAMICS, CERVIX uteri tumors
Abstract

Five diarylpentanol derivatives including two new compounds stellerasme A (1), stellerasme B (2) were isolated from the aerial parts ofStelleropsis tianschanica. Their structures were elucidated by various spectroscopic techniques (UV, IR, MS, CD, 1D and 2D NMR). All compounds were evaluated for their cytotoxicity activity against HeLa and KB cell lines, and compound1showed selective activities against HeLa cell line with an IC50value of 7.4 μM. [ABSTRACT FROM PUBLISHER]

Published
2016
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