1. Multiple Myeloma, Version 3.2017, NCCN Clinical Practice Guidelines in Oncology.
- Author
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Kumar SK, Callander NS, Alsina M, Atanackovic D, Biermann JS, Chandler JC, Costello C, Faiman M, Fung HC, Gasparetto C, Godby K, Hofmeister C, Holmberg L, Holstein S, Huff CA, Kassim A, Liedtke M, Martin T, Omel J, Raje N, Reu FJ, Singhal S, Somlo G, Stockerl-Goldstein K, Treon SP, Weber D, Yahalom J, Shead DA, and Kumar R
- Subjects
- Antineoplastic Agents supply & distribution, Antineoplastic Combined Chemotherapy Protocols standards, Asymptomatic Diseases, Chemotherapy, Adjuvant methods, Chemotherapy, Adjuvant standards, Humans, Immunoglobulins blood, Magnetic Resonance Imaging, Maintenance Chemotherapy methods, Maintenance Chemotherapy standards, Multiple Myeloma blood, Myeloma Proteins analysis, Positron Emission Tomography Computed Tomography, Radiotherapy, Adjuvant methods, Radiotherapy, Adjuvant standards, Serologic Tests, Standard of Care, Stem Cell Transplantation standards, Treatment Outcome, Antineoplastic Agents therapeutic use, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Medical Oncology standards, Multiple Myeloma diagnosis, Multiple Myeloma therapy, Stem Cell Transplantation methods
- Abstract
Multiple myeloma (MM) is caused by the neoplastic proliferation of plasma cells. These neoplastic plasma cells proliferate and produce monoclonal immunoglobulin in the bone marrow causing skeletal damage, a hallmark of multiple myeloma. Other MM-related complications include hypercalcemia, renal insufficiency, anemia, and infections. The NCCN Multiple Myeloma Panel members have developed guidelines for the management of patients with various plasma cell dyscrasias, including solitary plasmacytoma, smoldering myeloma, multiple myeloma, systemic light chain amyloidosis, and Waldenström's macroglobulinemia. The recommendations specific to the diagnosis and treatment of patients with newly diagnosed MM are discussed in this article., (Copyright © 2017 by the National Comprehensive Cancer Network.)
- Published
- 2017
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