1. The treatment of mycosis fungoides.
- Author
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Mestel DS, Beyer M, Steinhoff M, Sterry W, and Assaf C
- Subjects
- Antineoplastic Agents administration & dosage, Antineoplastic Agents adverse effects, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Clinical Trials as Topic, Humans, Mycosis Fungoides drug therapy, Mycosis Fungoides pathology, Mycosis Fungoides radiotherapy, Neoplasm Staging, PUVA Therapy methods, Photopheresis, Practice Guidelines as Topic, Skin Neoplasms drug therapy, Skin Neoplasms pathology, Skin Neoplasms radiotherapy, Treatment Outcome, Antineoplastic Agents therapeutic use, Mycosis Fungoides therapy, Skin Neoplasms therapy, Ultraviolet Therapy
- Abstract
Primary cutaneous T-cell lymphomas (PCLs) mycosis fungoides (MF) and Sézary syndrome (Ss) belong to the group of non-Hodgkin lymphomas (NHL), which are characterized by clonally proliferating CD4+ cells localized in the skin. Although there already exist many conventional skin-directed and systemic cytotoxic treatment options, in long-term only a transient remission without curative results will be reached in most cases. The aim of this article was to present actual assumed treatment modalities, as well as new therapeutic strategies which passed already through clinical trials showing promising results in the treatment of PCLs.
- Published
- 2008