1. Antibiotics prophylaxis at the time of catheter removal after radical prostatectomy: a systematic review of the literature and meta-analysis.
- Author
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Santos LLD, Fraga IA, Almeida VA, Santos AHR, Almeida IM, Nascimento TR, Porto BC, Passerotti CC, Artifon ELA, Otoch JP, and Cruz JASD
- Subjects
- Humans, Male, Catheters, Indwelling adverse effects, Urinary Catheterization adverse effects, Urinary Catheters adverse effects, Catheter-Related Infections prevention & control, Anti-Bacterial Agents therapeutic use, Anti-Bacterial Agents administration & dosage, Prostatectomy adverse effects, Prostatectomy methods, Antibiotic Prophylaxis methods, Device Removal, Urinary Tract Infections prevention & control, Urinary Tract Infections etiology
- Abstract
Purpose: To conduct a systematic literature review with meta-analysis to identify whether antibiotic prophylaxis after removal of the indwelling urinary catheter reduces posterior infections., Methods: A systematic literature review was conducted in the databases PubMed, Embase, Cochrane, Google Scholar, and Latin American and Caribbean Health Sciences Literature, using the keywords "antibiotics" AND "prostatectomy" AND "urinary catheter.", Results: Three articles were identified having the scope of our review, with 1,040 patients, which were subjected to our meta-analysis revealing a marginally significant decrease in the risk of urinary infection after indwelling urinary catheter removal (odds ratio-OR = 0.51; 95% confidence interval-95%CI 0.27-0.98; p = 0.04; I2 = 0%). No difference was found regarding the presence of bacteriuria (OR = 0.39; 95%CI 0.12-1.24; p = 0.11; I2 = 73%)., Conclusions: In our meta-analysis, there was a significant decrease in urinary tract infection with antibiotic prophylaxis after indwelling urinary catheter removal following radical prostatectomy.
- Published
- 2024
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