Author: "Joshi, Vivek" / Topic: antibacterial activity - Searchworks@Jio Institute Digital Library Search Results

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Start Over Author "Joshi, Vivek" Topic antibacterial activity

Author: Desai, N. C., Joshi, Vivek V., Rajpara, Kiran M., Vaghani, Hasit V., and Satodiya, Hitesh M.
Subjects: *THIAZOLE derivatives, *CHALCONES, *ORGANIC synthesis, *QUINOLINE derivatives, *PYRAZOLE derivatives, *ANTI-infective agents, *ANTIBACTERIAL agents, *ANTIPROTOZOAL agents
Abstract: A new series of quinolinylpyrazolinylthiazole derivatives (V) (12 examples) is synthesized from chalcones (I). [ABSTRACT FROM AUTHOR]
Published: 2014
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Author: Desai, Nisheeth C., Rajpara, Kiran M., and Joshi, Vivek V.
Subjects: *HETEROCYCLIC compounds synthesis, *PYRAZOLES, *PYRIDONE derivatives, *ANTIBACTERIAL agents, *PHARMACEUTICAL chemistry, *NUCLEAR magnetic resonance spectroscopy, *STAPHYLOCOCCUS aureus, *CELL-mediated cytotoxicity
Abstract: Abstract: A series of novel compounds 6-amino-1-((1,3-diphenyl-1H-pyrazole-4-yl)methyleneamino)-4-(aryl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitriles (4a–t) were synthesized and characterized by IR, 1H NMR, 13C NMR and mass spectral data. These compounds were screened for their in vitro antibacterial activity against Staphylococcus aureus, Streptococcus pyogenes (Gram positive), Escherichia coli, Pseudomonas aeruginosa (Gram negative) by serial broth dilution and cytotoxic activity (NIH 3T3 & HeLa) by MTT assay. The results indicated that compounds 4g, 4i, 4m, 4o, 4r and 4t exhibit potent antibacterial activity against bacterial strains at non-cytotoxic concentrations. [Copyright &y& Elsevier]
Published: 2013
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Author: Desai, Nisheeth C., Rajpara, Kiran M., and Joshi, Vivek V.
Subjects: *PYRIDONE derivatives, *HYDROXYPYRIDONES, *ANTIBACTERIAL agents, *ANTI-infective agents, *BIOCIDES
Abstract: Some of the title compounds (V), e.g. (Vc)-(Vf), show potent antibacterial activity against bacterial strains at no-cytotoxic concentrations. [ABSTRACT FROM AUTHOR]
Published: 2013
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Author: Desai, Nisheeth C., Rajpara, Kiran M., and Joshi, Vivek V.
Abstract: Two novel series of quinoline derivatives substituted with thiazolylpyrazole (V) or pyrimidine moieties (XI) are synthesized (yields not given) and screened for their antimicrobial activities. [ABSTRACT FROM AUTHOR]
Published: 2013
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