1. Antibiotic prophylaxis in children undergoing abdominal surgery for neoplastic diseases.
- Author
-
Pio L, Avanzini S, Paraboschi I, Wong M, Naselli A, Garaventa A, Conte M, Rosati U, Losurdo G, Fratino G, Martucciello G, Mattioli G, and Castagnola E
- Subjects
- Adolescent, Adult, Child, Child, Preschool, Female, Humans, Incidence, Infant, Male, Retrospective Studies, Surgical Wound Infection epidemiology, Young Adult, Abdominal Neoplasms surgery, Anti-Bacterial Agents therapeutic use, Antibiotic Prophylaxis, Cefazolin therapeutic use, Pelvic Neoplasms surgery, Surgical Wound Infection prevention & control
- Abstract
Little is known about the effectiveness of antibiotic prophylaxis for prevention of surgical site infections (SSIs) in paediatric abdominopelvic surgical oncology. A retrospective analysis was performed upon the incidence of SSIs in children receiving a 24-hour antibiotic prophylaxis with cefazolin for abdominopelvic oncological surgery. In all, 145 patients (57% females) with a median age of 4 years underwent surgical procedures for abdominopelvic tumours. No SSIs were detected, despite the various risk factors known to be associated with their occurrence (such as pre- and post- surgical chemotherapy, long hospitalization, intensive care unit admission and drain placement). Cefazolin prophylaxis seems to be safe and effective in preventing SSIs in children undergoing abdominopelvic surgery for oncological diseases.
- Published
- 2018