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Your search keyword '"Hatala M"' showing total 12 results
Start Over Author "Hatala M" Topic anti-bacterial agents
12 results on '"Hatala M"'

2. [The effect of the combination of cephalexin with tobramycin on experimental pyelonephritis (author's transl)].

Author

Hatala M, Morávek J, Liska M, Modr Z, and Prát V

Subjects
Administration, Oral, Animals, Cephalexin therapeutic use, Disease Models, Animal, Drug Synergism, Female, Injections, Intramuscular, Rats, Tobramycin therapeutic use, Anti-Bacterial Agents administration & dosage, Cephalexin administration & dosage, Pyelonephritis drug therapy, Tobramycin administration & dosage
Published
1976

3. Short-term prophylaxis in cardiovascular surgery.

Author

Jirícková J, Hatala M, Vanĕk I, Modr Z, and Firt P

Subjects
Adolescent, Adult, Aged, Aged, 80 and over, Cardiovascular Surgical Procedures, Child, Female, Humans, Male, Middle Aged, Anti-Bacterial Agents therapeutic use, Premedication
Published
1986

4. [A combination of amoxycillin with clavulanic acid (Augmentin) in various types of urinary tract infections caused by microbes producing beta-lactamase].

Author

Prát V, Horcicková M, Hatala M, Liska M, and Matousovic K

Subjects
Adolescent, Adult, Aged, Amoxicillin-Potassium Clavulanate Combination, Drug Combinations therapeutic use, Enterobacteriaceae enzymology, Female, Humans, Male, Middle Aged, Urinary Tract Infections etiology, beta-Lactamases biosynthesis, Amoxicillin therapeutic use, Anti-Bacterial Agents therapeutic use, Clavulanic Acids therapeutic use, Enterobacteriaceae Infections drug therapy, Urinary Tract Infections drug therapy
Published
1985

6. Pharmacokinetics of tobramycin in rats with reduced renal parenchyma and in experimental shock.

Author

Morávek J, Hatala M, Schück O, Prát V, Liska M, and Konícková Z

Subjects
Animals, Gentamicins blood, Half-Life, Kinetics, Rats, Tobramycin blood, Anti-Bacterial Agents pharmacology, Burns blood, Kidney physiopathology, Nephrectomy, Shock, Septic blood, Tobramycin pharmacology
Abstract

Ten days after four-fifths nephrectomy in rats (four-fifths of the renal parenchyma removed), the total and renal elimination constants of tobramycin were lowered by one-half. The biological half-life of tobramycin doubled. These results suggest that soon after nephrectomy the residual nephrons are able to increase the rate of excretion of tobramycin. The increase in mass of the remaining renal tissue between day 10 and day 80 after nephrectomy had no effect on the biological half-life, on the total and renal elimination constants, and on the renal clearance of tobramycin. During endotoxin shock and burn shock, concentrations of tobramycin in serum decreased at a slower rate. The highest serum concentrations of tobramycin were observed in rats with shock due to burns.

Published
1976
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7. Single dose of netilmicin in urinary tract infection.

Author

Prát V, Horcicková M, Hatala M, Matousovic K, and Milotová Z

Subjects
Adult, Aged, Clinical Trials as Topic, Female, Humans, Male, Middle Aged, Treatment Outcome, Anti-Bacterial Agents therapeutic use, Netilmicin therapeutic use, Urinary Tract Infections drug therapy
Published
1989

8. [Experimental model of infection].

Author

Hatala M, Spousta J, and Prát V

Subjects
Animals, Carbenicillin therapeutic use, Carboxylic Acids therapeutic use, Disease Models, Animal, Drug Synergism, Female, Gentamicins therapeutic use, Immunosuppressive Agents, Penicillins therapeutic use, Rats, Thiophenes therapeutic use, Anti-Bacterial Agents therapeutic use, Pseudomonas Infections drug therapy
Published
1973

10. [The antibacterial effect of prostatic secretion (author's transl)].

Author

Kohlícek J, Stánková T, Rydlinková J, Kocvara S, and Hatala M

Subjects
Adult, Age Factors, Bacteria, Bacteriolysis, Bacteriuria, Child, Female, Humans, Leukocyte Count, Male, Middle Aged, Semen, Sex Factors, Staphylococcus, Anti-Bacterial Agents isolation & purification, Prostate metabolism
Published
1974

12. Pharmacokinetics of tobramycin in rats with reduced renal parenchyma and in experimental shock

Author

Hatala M, V Prát, Zdenká Koničkova, Josef Morávek, Otto Schück, and Miroslav Liška

Subjects
medicine.medical_specialty, medicine.medical_treatment, Urology, urologic and male genital diseases, Kidney, Nephrectomy, Excretion, Pharmacokinetics, medicine, Tobramycin, Immunology and Allergy, Animals, business.industry, Shock, Septic, Surgery, Anti-Bacterial Agents, Rats, carbohydrates (lipids), Kinetics, Infectious Diseases, medicine.anatomical_structure, Renal Elimination, Shock (circulatory), Gentamicin, medicine.symptom, Gentamicins, business, Burns, medicine.drug, Half-Life
Abstract

Ten days after four-fifths nephrectomy in rats (four-fifths of the renal parenchyma removed), the total and renal elimination constants of tobramycin were lowered by one-half. The biological half-life of tobramycin doubled. These results suggest that soon after nephrectomy the residual nephrons are able to increase the rate of excretion of tobramycin. The increase in mass of the remaining renal tissue between day 10 and day 80 after nephrectomy had no effect on the biological half-life, on the total and renal elimination constants, and on the renal clearance of tobramycin. During endotoxin shock and burn shock, concentrations of tobramycin in serum decreased at a slower rate. The highest serum concentrations of tobramycin were observed in rats with shock due to burns.

Published
1976

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