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1. What potential do heterobivalent inhibitors have for the treatment of severe allergic reactions?

Author

Handlogten MW, Serezani AP, Kaplan MH, and Bilgicer B

Subjects
Allergens administration & dosage, Allergens immunology, Animals, Anti-Allergic Agents chemical synthesis, Anti-Allergic Agents immunology, Antibody Affinity, Antibody Specificity, Antigen-Antibody Reactions drug effects, Binding Sites, Antibody, Desensitization, Immunologic, Drug Design, Drug Evaluation, Preclinical, Half-Life, Haptens immunology, Histamine Release drug effects, Humans, Hypersensitivity, Immediate drug therapy, Hypersensitivity, Immediate immunology, Immunodominant Epitopes immunology, Immunoglobulin Fab Fragments immunology, Indoles chemical synthesis, Ligands, Mast Cells metabolism, Nitrofurans chemical synthesis, Anti-Allergic Agents therapeutic use, Hypersensitivity, Immediate prevention & control, Immunoglobulin E immunology, Indoles therapeutic use, Nitrofurans therapeutic use
Published
2014
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