1. Seizure Freedom in Temporal Plus Epilepsy Surgery Following Stereo-Electroencephalography.
- Author
-
Bottan JS, Suller Marti A, Parrent AG, MacDougall KW, McLachlan RS, Burneo JG, and Steven DA
- Subjects
- Adult, Cerebral Cortex physiopathology, Cerebral Cortex surgery, Drug Resistant Epilepsy diagnosis, Drug Resistant Epilepsy physiopathology, Electroencephalography, Epilepsies, Partial diagnosis, Epilepsies, Partial physiopathology, Epilepsies, Partial surgery, Epilepsy, Reflex diagnosis, Epilepsy, Reflex physiopathology, Epilepsy, Temporal Lobe diagnosis, Epilepsy, Temporal Lobe physiopathology, Female, Humans, Male, Middle Aged, Neuronavigation, Neurosurgical Procedures methods, Prefrontal Cortex physiopathology, Retrospective Studies, Stereotaxic Techniques, Treatment Outcome, Anterior Temporal Lobectomy methods, Drug Resistant Epilepsy surgery, Epilepsy, Reflex surgery, Epilepsy, Temporal Lobe surgery, Prefrontal Cortex surgery
- Abstract
Background: "Temporal plus" epilepsy (TPE) is a term that is used when the epileptogenic zone (EZ) extends beyond the boundaries of the temporal lobe. Stereotactic electroencephalography (SEEG) has been essential to identify additional EZs in adjacent structures that might be part of the temporal lobe/limbic network., Objective: We present a small case series of temporal plus cases successfully identified by SEEG who were seizure-free after resective surgery., Methods: We conducted a retrospective analysis of 156 patients who underwent SEEG in 5 years. Six cases had TPE and underwent anterior temporal lobectomy (ATL) with additional extra-temporal resections., Results: Five cases had a focus on the right hemisphere and one on the left. Three cases were non-lesional and three were lesional. Mean follow-up time since surgery was 2.9 years (SD ± 1.8). Three patients had subdural electrodes investigation prior or in addition to SEEG. All patients underwent standard ATL and additional extra-temporal resections during the same procedure or at a later date. All patients were seizure-free at their last follow-up appointment (Engel Ia = 3; Engel Ib = 2; Engel Ic = 1). Pathology was nonspecific/gliosis for all six cases., Conclusion: TPE might explain some of the failures in temporal lobe epilepsy surgery. We present a small case series of six patients in whom SEEG successfully identified this phenomenon and surgery proved effective.
- Published
- 2020
- Full Text
- View/download PDF