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Tricyclic benzopyrans are medicinally important biologically active compounds. Synthesis of a series of tricyclic benzopyrans derivatives via N-Heterocyclic carbene (NHC) catalyzed annulation of enals to α-methylidenetetralones/chromanones is described. This reaction afforded the benzopyrans in high yield with aromatic as well as aliphatic enals.

A nucleophilic heterocyclic carbene-mediated intramolecular homoenolate reaction strategy for the efficient synthesis of cyclopentene-fused macrocycles is reported.

Nucleophilic heterocyclic carbene (NHC)-catalyzed ­annulation strategy has been utilized for the efficient synthesis of styrenyl-substituted cyclopentenes from 2,4-dienones.

The facile synthesis of 1,3,4-trisubstituted cyclopentenes via homoenolate annulation of enals with heterocycle substituted chalcones is described.

Tricyclic benzopyrans are medicinally important biologically active compounds. Synthesis of a series of tricyclic benzopyrans derivatives via N-Heterocyclic carbene (NHC) catalyzed annulation of enals to α-methylidenetetralones/chromanones is described. This reaction afforded the benzopyrans in high yield with aromatic as well as aliphatic enals.

Aryl, hetaryl, alkyl and alkenyl enals are reacting with 2-aroylidene substituted alkylbenzofuran-3-ones providing the corresponding products as single diastereomers.

A nucleophilic heterocyclic carbene-mediated intramolecular homoenolate reaction strategy for the efficient synthesis of cyclopentene-fused macrocycles is reported.

Homoenolate annulation of vinyl ketones led to the synthesis of dihydropyranones in contrast to cyclopentenes obtained by the homoenolate annulation of chalcones, another class of α,β-unsaturated ketones.

A nucleophilic heterocyclic carbene mediated homoenolate annulation of enals to aurone analogs leading to the efficient synthesis of cyclopentene-fused spirobenzofuran-3-ones is reported.

A simple NHC-catalyst promotes the reaction of enals with dienones to give unexpected cyclopentene derivatives (III).

The facile synthesis of 1,3,4-trisubstituted cyclopentenes via homoenolate annulation of enals with heterocycle substituted chalcones is described.

The homoenolate annulation to vinyl ketones gives dihydropyranone derivatives in contrast to cyclopentenes resulting from homoenolate reaction of chalcones.