1. Insights in to the pathogenesis of axial spondyloarthropathy based on gene expression profiles
- Author
-
Tammy M. Martin, Srilakshmi M Sharma, Justine R. Smith, James T. Rosenbaum, Jinnell A. Lewis, Stephen R. Planck, Tessa N. Diebel, Carrie R. Austin, Christina A. Harrington, and Dongseok Choi
- Subjects
musculoskeletal diseases ,Pathology ,medicine.medical_specialty ,Axial skeleton ,Spondyloarthropathy ,Immunology ,Biology ,Pathogenesis ,03 medical and health sciences ,0302 clinical medicine ,Rheumatology ,Internal medicine ,medicine ,Immunology and Allergy ,Spondylarthropathies ,030304 developmental biology ,030203 arthritis & rheumatology ,0303 health sciences ,Ankylosing spondylitis ,Enthesis ,medicine.disease ,3. Good health ,Gene expression profiling ,stomatognathic diseases ,medicine.anatomical_structure - Abstract
Introduction Axial spondyloarthropathy (SpA) is a group of inflammatory diseases, with ankylosing spondylitis as the prototype. SpA affects the axial skeleton, entheses, joints and, at times, the eyes. This study tested the hypothesis that SpA is characterized by a distinct pattern of gene expression in peripheral blood of affected individuals compared with healthy controls.
- Published
- 2009
- Full Text
- View/download PDF