1. [Natural resistance factors in brucellosis]
- Author
-
V M, Safronova, N A, Loktev, L V, Liapustina, and O V, Logvinenko
- Subjects
Male ,Phagocytosis ,Neutrophils ,Guinea Pigs ,Animals ,Opsonin Proteins ,Lysosomes ,Brucellosis ,Immunity, Innate ,Rats, Inbred F344 ,Rats - Abstract
A higher level of the opsono-cytophagous capacity of the blood and the quantitative content of lysosomal cationic proteins in polymorphonuclear neutrophils in the blood of Fischer rats in comparison with the corresponding characteristics in normal guinea pigs has proved to be conductive to more active elimination of the infective agent from the body of the animals after their infection with brucellosis. The indices characterizing the activity and intensity of the phagocytosis of brucellae by polymorphonuclear neutrophils of the blood in combination with the determination of the amount of cationic proteins in these cells permit the objective characterization of the level of nonspecific resistance to brucellosis.
- Published
- 1991