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Transendoscopic neodymium:yttrium-aluminum-garnet (Nd:YAG) laser was used to treat 12 standing horses with epiglottic entrapment (EE) or dorsal displacement of the soft palate (DDSP), or both. In four horses, transendoscopic laser staphylectomy was performed. The most common presenting complaints were respiratory stridor, cough, and exercise intolerance. Ten horses with EE healed without epiglottic complications; in one horse, partial adhesion of the aryepiglottic fold to one side of the epiglottis was corrected surgically through a laryngotomy incision. One horse with DDSP had no further signs, one continued to have continual DDSP, and two had induced DDSP. Transendoscopic Nd:YAG laser proved to be a feasible means of correcting EE and selected cases of DDSP.

Renal and peripheral arteriovenous differences (A-V/A) of albumin, peptide-N and α-amino-N were compared in normal and aminonucleoside treated rats. Significant accumulations of peptide-N were demonstrated in the renal venous plasma of nephrotic animals which was supported by similar results obtained when kidney and liver slices were incubated with RISA. Specific activity ratios (F/P) were determined for the TCA soluble (F) and precipitable (P) fractions of plasma from 5 normal persons, 8 patients with idiopathic nephrotic syndrome or membranous glomerulonephritis and 3 with cirrhosis. A significant difference was obtained between the normal and hypoalbuminemic subjects attributed to the greater accumulation of radioactivity in the protein-free filtrate in the latter group. These data suggest accelerated proteolytic activity in experimental and cliincal nephrotic syndromes but do not indicate that other abnormalities of albumin metabolism are not operative or that the defect is specific for renal disease.